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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Antimicrobial Stewardship Clear all
Enrolling by invitation Not applicable Interventional

Point of Care Respiratory Pathogen Testing for Antibiotic Stewardship in Primary Care

NCT06765135
View directory record Official record
Conditions
Upper Respiratory Infection
Interventions
Clinician Survey, Focus Group, Biofire Spotfire Respiratory (R) panel, Patient Survey
Behavioral · Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
8,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Recruiting Phase 4 Interventional

Allergy Delabeling in Antibiotic Stewardship - Intervention

NCT07133074
View directory record Official record
Conditions
Beta Lactam Allergy, Hematologic Malignancy
Interventions
RENEW-IN Algorithm for assessment of a beta-lactam intervention, EMR Review
Diagnostic Test · Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
3,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Rapid Diagnostics for Upper Respiratory Infections in the Emergency Department

NCT02957136
View directory record Official record
Conditions
Respiratory Tract Infections, Influenza, Human, Common Cold
Interventions
Rapid respiratory pathogen nucleic acid amplification test
Device
Lead sponsor
University of California, Davis
Other
Eligibility
1 Year to 101 Years
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Sep 27, 2026, 8:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Merck IISP Stewardship Grant for Antibiotic Best Practices

NCT01573195
View directory record Official record
Conditions
Antibiotic Resistant Infection
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Not listed
Enrollment
1,285 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 17, 2014 · Synced Sep 27, 2026, 8:24 AM EDT
Recruiting Not applicable Interventional

Diagnostic Stewardship Intervention to Reduce Inappropriate Antibiotic Use for Urinary Tract Infections in Primary Care

NCT07246837
View directory record Official record
Conditions
Urinary Tract Infection(UTI), Antimicrobial Stewardship, Primary Care
Interventions
MSCC Educational Tool
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Antimicrobial Stewardship for Primary Care Pediatricians

NCT01806103
View directory record Official record
Conditions
Acute Sinusitis, Streptococcal Pharyngitis, Pneumonia, Viral Infection
Interventions
Antimicrobial Stewardship Bundle
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2013 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Phase 2 Interventional Results available

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

NCT04983901
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Imipenem/Cilastatin/Relebactam, Cefepime, Meropenem, Piperacillin-Tazobactam, Vancomycin, Daptomycin, Linezolid
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Ventilator-associated Pneumonia (VAP) Diagnostic Stewardship Trial

NCT05176353
View directory record Official record
Conditions
VAP - Ventilator Associated Pneumonia
Interventions
VAP diagnostic stewardship bundle
Other
Lead sponsor
University of Michigan
Other
Eligibility
Not listed
Enrollment
4,892 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Sep 27, 2026, 8:24 AM EDT
Completed No phase listed Observational

Antimicrobial Drug Use and Resistant Staphylococcus Aureus

NCT01075451
View directory record Official record
Conditions
Staphylococcus Aureus
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 19, 2013 · Synced Sep 27, 2026, 8:24 AM EDT
Active, not recruiting Not applicable Interventional

RELAX: Reducing Length of Antibiotics for Children With Ear Infections

NCT05608993
View directory record Official record
Conditions
Acute Otitis Media, Pediatric Infectious Disease, Ear Infection
Interventions
High Intensity Intervention, Low Intensity Intervention
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
2 Years to 17 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions

NCT06027593
View directory record Official record
Conditions
Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis
Interventions
Quasi experimental intervention
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
26,139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

The INSPIRE-ASP UTI Trial

NCT03697096
View directory record Official record
Conditions
Urinary Tract Infection (UTI)
Interventions
Routine Care, INSPIRE CPOE Smart Prompt
Other
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
18 Years and older
Enrollment
55,412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
59
States / cities
Riverside, California • San Jose, California • Thousand Oaks, California + 51 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 27, 2026, 8:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Supracondylar Pinning Antibiotic Stewardship (SPAS) Trial

NCT04288206
View directory record Official record
Conditions
Supracondylar Humerus Fracture, Infection
Interventions
Cefazolin, normal saline
Drug
Lead sponsor
Legacy Health System
Other
Eligibility
0 Years to 18 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Post-discharge Antimicrobial Use

NCT05471726
View directory record Official record
Conditions
Infections
Interventions
Prospective audit-and-feedback
Behavioral
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
5
States / cities
Indianapolis, Indiana • Iowa City, Iowa • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 27, 2026, 8:24 AM EDT
Completed No phase listed Observational

Blood Culture Improvement Guidelines and Diagnostic Stewardship for Antibiotic Reduction in Critically Ill Children

NCT03441126
View directory record Official record
Conditions
Sepsis, Bacteremia
Interventions
Multicenter Quality Improvement program
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
5
States / cities
St Louis, Missouri • Cleveland, Ohio • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxygenation

NCT05172791
View directory record Official record
Conditions
Pneumonia
Interventions
Antibiotic stewardship messaging
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia

NCT03218397
View directory record Official record
Conditions
Gram-negative Bacteremia
Interventions
Accelerate PhenoTest™ BC Kit, Standard Culture and AST
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Sep 27, 2026, 8:24 AM EDT
Enrolling by invitation No phase listed Observational

Allergy Delabeling in Antibiotic Stewardship - Evaluations

NCT06967467
View directory record Official record
Conditions
Beta Lactam Allergy in Patients With a Hematologic Malignancy
Interventions
Semi-structured interview, Survey, Ethnographic observation
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

INSPIRE Trial for Skin and Soft Tissue Infections

NCT05423756
View directory record Official record
Conditions
Skin and Soft Tissue (SST) Infection
Interventions
Arm 1: Routine Care, Arm 2: INSPIRE Stewardship Bundle for Skin and Soft Tissue Infection
Other
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
18 Years and older
Enrollment
118,562 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
102
States / cities
Riverside, California • San Jose, California • Thousand Oaks, California + 80 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Not yet recruiting Not applicable Interventional

De-implementing PreOp Urine Testing

NCT07411209
View directory record Official record
Conditions
Urinary Tract Infection, Asymptomatic Bacteriuria
Interventions
Interventional Project Site Visit
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Phase 4 Interventional

Fecal Microbiota Transplant

NCT04090346
View directory record Official record
Conditions
Clostridium Difficile Infection
Interventions
Fecal Microbiota Transplant
Drug
Lead sponsor
Methodist Health System
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Using Behavioral Science to Reduce Inappropriate Antibiotic Use in Acute Care Settings

NCT03711292
View directory record Official record
Conditions
Antimicrobial Stewardship, Acute Bronchitis, Upper Respiratory Infection
Interventions
Antibiotic Stewardship
Behavioral
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2023 · Synced Sep 27, 2026, 8:24 AM EDT
Completed No phase listed Observational

Precision Antimicrobial STewardship for Clostridioides DIfficile Prevention

NCT05508607
View directory record Official record
Conditions
CDI
Interventions
CDI-risk Classification Tool
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
13,319 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Sep 27, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

NCT04366440
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Order set review and modification with facilitation, Order set review and modification
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
0 Days to 75 Years
Enrollment
18,267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
10
States / cities
St. Petersburg, Florida • Boston, Massachusetts • Ann Arbor, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 27, 2026, 8:24 AM EDT