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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Aphasia Clear all
Completed Not applicable Interventional

Strategies to Accommodate Reading (STAR)

NCT03312270
View directory record Official record
Conditions
Aphasia
Interventions
Multimodality information comprehension
Behavioral
Lead sponsor
Miami University
Other
Eligibility
19 Years to 90 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Oxford, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 4, 2026, 9:38 PM EDT
Withdrawn Not applicable Interventional

tDCS to Treat Subacute Aphasia

NCT04048668
View directory record Official record
Conditions
Aphasia, Stroke, Acute
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

Treatment Intensity - Apraxia of Speech

NCT02332915
View directory record Official record
Conditions
Aphasia, CVA, Apraxia of Speech
Interventions
Sound Production Treatment (SPT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) and Intensive Therapy in Aphasia

NCT03510182
View directory record Official record
Conditions
Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 19, 2021 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Phase 1 Interventional Results available

Transcranial Magnetic Stimulation to Improve Speech in Aphasia

NCT00608582
View directory record Official record
Conditions
Aphasia, Cerebrovascular Stroke
Interventions
Transcranial Magnetic Stimulation, Repetitive
Device
Lead sponsor
Boston University
Other
Eligibility
45 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

Phonomotor Treatment of Word Retrieval Deficits in Individuals With Aphasia

NCT01163461
View directory record Official record
Conditions
Aphasia
Interventions
speech therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia

NCT04984239
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Acceptance and Commitment Therapy for aphasia
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 4, 2026, 9:38 PM EDT
Completed No phase listed Observational

Florbetaben PET Imaging in PPA

NCT04720001
View directory record Official record
Conditions
Primary Progressive Aphasia, Alzheimer Disease
Interventions
Florbetaben F18, PET
Drug · Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 4, 2026, 9:38 PM EDT
Recruiting Not applicable Interventional

Recovery From Post-Stroke Aphasia With rTMS Targeting Left or Right Anterior Temporal Lobe

NCT07608588
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
continuous Theta Burst Stimulation, intermittent Theta Burst Stimulation, Transcranial Magnetic Stimulation Sham, Semantic Feature Analysis
Device · Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 4, 2026, 9:38 PM EDT
Completed No phase listed Observational

Tau Imaging in Young Onset Dementia

NCT02289118
View directory record Official record
Conditions
Alzheimer's Disease, Early Onset, Logopenic Progressive Aphasia, Posterior Cortical Atrophy (PCA)
Interventions
[18F]-T807 imaging tracer
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Sep 4, 2026, 9:38 PM EDT
Recruiting Not applicable Interventional

Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke

NCT06048159
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
HD-tACS, Sham HD-tACS
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 4, 2026, 9:38 PM EDT
Recruiting Not applicable Interventional

Telerehabilitation for Aphasia (TERRA)

NCT04682223
View directory record Official record
Conditions
Aphasia, Stroke, Stroke Rehabilitation
Interventions
Semantically-focused therapy tasks, Phonologically-focused therapy tasks
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 4, 2026, 9:38 PM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 25, 2018 · Synced Sep 4, 2026, 9:38 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Central Mechanisms in Speech Motor Control Studied With H215O PET

NCT00001308
View directory record Official record
Conditions
Communication Disorder, Healthy, Stuttering, Tourette Syndrome, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
1,163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

Exercise as an Adjuvant to Aphasia Therapy

NCT01113879
View directory record Official record
Conditions
Aphasia
Interventions
Aerobic exercise, Stretching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 95 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2019 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Phase 2 Interventional Results available

Speech Entrainment for Aphasia Recovery

NCT04364854
View directory record Official record
Conditions
Aphasia, Aphasia Non Fluent, Stroke
Interventions
SET (Speech Entrainment Therapy) 3 weeks, SET (Speech Entrainment Therapy) 4.5 weeks, SET (Speech Entrainment Therapy) 6 weeks, No Therapy 6 Weeks
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 81 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes

NCT01979159
View directory record Official record
Conditions
Apraxia of Speech, Aphasia
Interventions
Combined Aphasia and Apraxia of Speech Treatment (CAAST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Phase 1 Interventional

Transcranial Direct Current Stimulation and Aphasia Language Therapy

NCT01486654
View directory record Official record
Conditions
Nonfluent Aphasia, Stroke
Interventions
Transcranial Direct Current Stimulation - Cathodal stimulation, Transcranial Direct Current Stimulation - Anodal stimulation, Transcranial Direct Current Stimulation - Sham stimulation
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Treating Intention In Aphasia: Neuroplastic Substrates

NCT00567242
View directory record Official record
Conditions
Aphasia, Cerebrovascular Accident
Interventions
Word-finding with intention component, Word-finding with no intention component
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 95 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 2, 2012 · Synced Sep 4, 2026, 9:38 PM EDT
Recruiting Not applicable Interventional

Remotely-supervised Neuromodulation in PPA

NCT07260253
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease, Logopenic Progressive Aphasia (LPA), Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA)
Interventions
Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active, Remotely Supervised Transcranial Direct Current Stimulation - Sham
Behavioral · Device
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Not applicable Interventional

Therapy for Reading Problems in Adults After Brain Injury

NCT00064805
View directory record Official record
Conditions
Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
Interventions
Cognitive Therapy to Improve Reading
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Phase 1 Interventional

PiB PET Scanning in Speech and Language Based Dementias

NCT01623284
View directory record Official record
Conditions
PPA, Primary Progressive Aphasia, Aphasia, Non-fluent Aphasia, Semantic Dementia, Apraxia of Speech, Primary Progressive Nonfluent Aphasia, Progressive Aphasia
Interventions
C-11 PiB, F-18 FDG
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 21, 2015 · Synced Sep 4, 2026, 9:38 PM EDT
Completed No phase listed Observational

TMS as a Biological Marker of Neuroplasticity

NCT02867670
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 4, 2026, 9:38 PM EDT
Completed Phase 1 Interventional

Davunetide (AL-108) in Predicted Tauopathies - Pilot Study

NCT01056965
View directory record Official record
Conditions
Predicted Tauopathies, Including, Progressive Supranuclear Palsy, Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17, Corticobasal Degeneration Syndrome, Progressive Nonfluent Aphasia
Interventions
davunetide (AL-108, NAP), Placebo nasal spray
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Sep 4, 2026, 9:38 PM EDT