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ClinicalTrials.gov public records Last synced Sep 17, 2026, 6:05 AM EDT

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Showing 1–24 of 48 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Apnea+Hypopnea Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00107848
View directory record Official record
Conditions
Narcolepsy, Sleep Apnea, Obstructive
Interventions
Modafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
6 Years to 16 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
55
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

NCT04950894
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive, Apnea, Obstructive Sleep, Apnea+Hypopnea, Hypopnea, Sleep
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
LivaNova
Industry
Eligibility
22 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
19
States / cities
Birmingham, Alabama • Tucson, Arizona • Roseville, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 17, 2026, 6:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

TipTraQ Home Sleep Test Validation Study, Duke

NCT06351878
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
PranaQ Pte. Ltd.
Industry
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Early Phase 1 Interventional

Promoting Continuous Positive Airway Pressure (CPAP) Adherence

NCT01335854
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Web-based Access to CPAP Data, Web-based Access to CPAP Data with Financial Incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2014 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Phase 4 Interventional Results available

Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression

NCT00518986
View directory record Official record
Conditions
Sleep Disorders, Obstructive Sleep Apnea, Major Depressive Disorder, Dysthymic Disorder
Interventions
armodafinil, placebo
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
62
States / cities
Jasper, Alabama • Phoenix, Arizona • Tucson, Arizona + 50 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

NCT04575740
View directory record Official record
Conditions
Sleep Apnea
Interventions
PAP
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 80 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Phase 1 Interventional Results available

A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease

NCT04647383
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders
Interventions
Placebo, Lemborexant 10 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
11
States / cities
Glendale, Arizona • San Diego, California • Brandon, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 17, 2026, 6:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessment of PPG & PAT to Detect Upper Airway Obstruction in Patients With Obstructive Sleep Apnea

NCT01831583
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Measurement of PPG waveforms, Measurement of Pulse Arrival Time (PAT)
Device
Lead sponsor
Sotera Wireless, Inc.
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2013 · Synced Sep 17, 2026, 6:05 AM EDT
Not yet recruiting Not applicable Interventional

Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).

NCT07613281
View directory record Official record
Conditions
Snoring, OSA - Obstructive Sleep Apnea
Interventions
Palatal Implant System
Device
Lead sponsor
Serene Sleep, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
San Francisco, California • Evans, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 17, 2026, 6:05 AM EDT
Not listed No phase listed Observational

Is My Sleep Tracker Tracking my Sleep?

NCT06174558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Sleep Tracking Devices
Device
Lead sponsor
Respiratory Specialists
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Wyomissing, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 17, 2026, 6:05 AM EDT
Completed No phase listed Observational

Extension Study of Original Protocol AERO C009 for Obstructive Sleep Apnea-hypopnea

NCT00849043
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, Obstructive Sleep Apnea, OSAH
Interventions
Not listed
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
13
States / cities
Wallingford, Connecticut • Gainesville, Florida • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2011 · Synced Sep 17, 2026, 6:05 AM EDT
Terminated Not applicable Interventional Results available

CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting

NCT00588848
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Autoadjusting CPAP (VPAP Auto), CPAP
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2019 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Comparison of SomnaPatch With Polysomnography in Sleep Disordered Breathing

NCT02034175
View directory record Official record
Conditions
Obstructive Sleep Apnea, Central Sleep Apnea, Mixed Sleep Apnea, Cheyne-Stokes Respiration
Interventions
SomnaPatch, Polysomnography
Device
Lead sponsor
Somnarus Inc
Industry
Eligibility
20 Years to 85 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
3
States / cities
Little Rock, Arkansas • Burlingame, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Phase 4 Interventional Results available

Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory Performance

NCT00711516
View directory record Official record
Conditions
Excessive Sleepiness
Interventions
Armodafinil, Placebo
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
Burlingame, California • San Diego, California • Stanford, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults

NCT00745251
View directory record Official record
Conditions
Sleep Apnea
Interventions
VI-0521, placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
30 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Phase 3 Interventional Results available

Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

NCT00078312
View directory record Official record
Conditions
Narcolepsy, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Shift-Work Sleep Disorder
Interventions
CEP-10953 (Armodafinil)
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
41
States / cities
Peoria, Arizona • Phoenix, Arizona • Tucson, Arizona + 35 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Sep 17, 2026, 6:05 AM EDT
Terminated No phase listed Observational Results available

Prospective Study to Evaluate Outcomes From Transoral BOT Resection for OSAHS

NCT01107795
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Interventions
Transoral Robotic Surgery
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Effect of Added Varnum Mouthpiece on Pharyngeal Collapsibility and Sleep Apnea Severity in Mouth Breathers.

NCT02738255
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Varnum mouthpiece
Device
Lead sponsor
David Andrew Wellman
Other
Eligibility
21 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2022 · Synced Sep 17, 2026, 6:05 AM EDT
Completed No phase listed Observational

Point-of-care-Ultrasound for Sleep Apnea

NCT04443582
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Rakesh Sondekoppam Vijayashankar
Other
Eligibility
18 Years to 85 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Transcend Auto vs Commercially Available Device Clinical Evaluation for Treatment of Obstructive Sleep Apnea (OSA)

NCT01799265
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Somnetics Transcend Auto, Respironics REMstar Auto with C-Flex
Device
Lead sponsor
Somnetics International, Inc.
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
3
States / cities
Coon Rapids, Minnesota • Plymouth, Minnesota • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 17, 2026, 6:05 AM EDT
Completed Phase 4 Interventional

Randomized Study of Provent Versus Sham Device to Treat Obstructive Sleep Apnea

NCT00772044
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, OSA, OSAH
Interventions
Provent Professional Sleep Apnea Therapy Device, Sham Device
Device
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
17
States / cities
Glendale, Arizona • Phoenix, Arizona • Redwood City, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2010 · Synced Sep 17, 2026, 6:05 AM EDT
Completed No phase listed Observational

Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea

NCT01610648
View directory record Official record
Conditions
Sleep Apnea, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Sep 17, 2026, 6:05 AM EDT
Recruiting No phase listed Observational

Pediatric Post-Approval Registry

NCT04457154
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Inspire Upper Airway Stimulation System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
8
States / cities
Aurora, Colorado • Atlanta, Georgia • Durham, North Carolina + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 17, 2026, 6:05 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

NCT04118387
View directory record Official record
Conditions
Sleep Disordered Breathing, Able Bodied
Interventions
Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 17, 2026, 6:05 AM EDT