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ClinicalTrials.gov public records Last synced Oct 5, 2026, 1:21 AM EDT

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Showing 25–48 of 49 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Apnea+Hypopnea Clear all
Completed Phase 4 Interventional

Randomized Study of Provent Versus Sham Device to Treat Obstructive Sleep Apnea

NCT00772044
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, OSA, OSAH
Interventions
Provent Professional Sleep Apnea Therapy Device, Sham Device
Device
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
17
States / cities
Glendale, Arizona • Phoenix, Arizona • Redwood City, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2010 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy

NCT01895062
View directory record Official record
Conditions
Airway Obstruction, Apnea, Hypopnea
Interventions
Airway Management System (AMS)
Device
Lead sponsor
5i Sciences, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 1 Interventional Results available

A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease

NCT04647383
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders
Interventions
Placebo, Lemborexant 10 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
11
States / cities
Glendale, Arizona • San Diego, California • Brandon, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 5, 2026, 1:21 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

NCT04118387
View directory record Official record
Conditions
Sleep Disordered Breathing, Able Bodied
Interventions
Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 3 Interventional Results available

Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

NCT00078312
View directory record Official record
Conditions
Narcolepsy, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Shift-Work Sleep Disorder
Interventions
CEP-10953 (Armodafinil)
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
41
States / cities
Peoria, Arizona • Phoenix, Arizona • Tucson, Arizona + 35 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2013 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional Results available

Use of Capnography in EGD and Colonoscopy With Moderate Sedation.

NCT01994785
View directory record Official record
Conditions
Hypoxia, Apnea, Hypotension, Hypopnea
Interventions
Capnographic Monitoring
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Independence, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 5, 2026, 1:21 AM EDT
Not yet recruiting Not applicable Interventional

Pediatric/Adolescent WatchPAT 400 Reliability Pilot Study

NCT07851402
View directory record Official record
Conditions
Obstructive Sleep Apnea Sleep Apnea, Obstructive Pediatric Obstructive Sleep Apnea Sleep Disordered Breathing Snoring
Interventions
WatchPAT 400
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
6 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hummelstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional Results available

DeVilbiss AutoAdjust With SmartFlex Comparative Study

NCT01203956
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
SmartFlex, Standard
Device
Lead sponsor
DeVilbiss Healthcare LLC
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Dallas, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 5, 2026, 1:21 AM EDT
Recruiting No phase listed Observational

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

NCT07113288
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Inspire® UAS System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
5
States / cities
Colorado Springs, Colorado • Bradenton, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional Results available

Transcend Auto vs Commercially Available Device Clinical Evaluation for Treatment of Obstructive Sleep Apnea (OSA)

NCT01799265
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Somnetics Transcend Auto, Respironics REMstar Auto with C-Flex
Device
Lead sponsor
Somnetics International, Inc.
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
3
States / cities
Coon Rapids, Minnesota • Plymouth, Minnesota • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00107809
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Modafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
6 Years to 16 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
60
States / cities
Birmingham, Alabama • Tucson, Arizona • Fort Smith, Arkansas + 51 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation

NCT06560411
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Diseases (NMD)
Interventions
Non-Invasive Ventilation
Device
Lead sponsor
Breas Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Scottsdale, Arizona • San Diego, California • Colorado Springs, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 4 Interventional Results available

The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea

NCT02714400
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Venlafaxine, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 5, 2026, 1:21 AM EDT
Completed No phase listed Observational

Point-of-care-Ultrasound for Sleep Apnea

NCT04443582
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Rakesh Sondekoppam Vijayashankar
Other
Eligibility
18 Years to 85 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 28, 2022 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 4 Interventional Results available

Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients

NCT00804349
View directory record Official record
Conditions
Heart Failure, Sleep Apnea Syndromes
Interventions
Autotitrating Positive Airway Pressure
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 4 Interventional Results available

The Impact of Arousal Threshold in Obstructive Sleep Apnea

NCT02264353
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Donepezil, placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

NCT04950894
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive, Apnea, Obstructive Sleep, Apnea+Hypopnea, Hypopnea, Sleep
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
LivaNova
Industry
Eligibility
22 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
19
States / cities
Birmingham, Alabama • Tucson, Arizona • Roseville, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional Results available

Effect of Added Varnum Mouthpiece on Pharyngeal Collapsibility and Sleep Apnea Severity in Mouth Breathers.

NCT02738255
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Varnum mouthpiece
Device
Lead sponsor
David Andrew Wellman
Other
Eligibility
21 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Not applicable Interventional

The Effect of Mouth Closure on Airflow in OSA

NCT06547658
View directory record Official record
Conditions
Hypopnea, Sleep
Interventions
Mouth closure
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 89 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)

NCT03299023
View directory record Official record
Conditions
Obstructive Sleep Apnea, Orthodontic Tooth Movement, Apnea, Sleep Disordered Breathing
Interventions
Medibyte Portable Monitor
Other
Lead sponsor
Harvard School of Dental Medicine
Other
Eligibility
8 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 5, 2026, 1:21 AM EDT
Enrolling by invitation No phase listed Observational

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

NCT03062748
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 5, 2026, 1:21 AM EDT
Completed No phase listed Observational

Extension Study of Original Protocol AERO C009 for Obstructive Sleep Apnea-hypopnea

NCT00849043
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, Obstructive Sleep Apnea, OSAH
Interventions
Not listed
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
13
States / cities
Wallingford, Connecticut • Gainesville, Florida • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2011 · Synced Oct 5, 2026, 1:21 AM EDT
Completed Phase 3 Interventional Results available

Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00228566
View directory record Official record
Conditions
Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
Interventions
Armodafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
43
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2013 · Synced Oct 5, 2026, 1:21 AM EDT
Terminated Not applicable Interventional Results available

CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting

NCT00588848
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Autoadjusting CPAP (VPAP Auto), CPAP
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 5, 2026, 1:21 AM EDT