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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:59 PM EDT

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Showing 625–648 of 1,077 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Apnea Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Sleep and Breathing in the General Population - Chemical Stimuli

NCT04720547
View directory record Official record
Conditions
Sleep-disordered Breathing
Interventions
Zolpidem, No Treatment
Drug · Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 89 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 22, 2026, 7:59 PM EDT
Active, not recruiting No phase listed Observational

Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy

NCT02917876
View directory record Official record
Conditions
Obstructive Sleep Apnea, Pregnancy, Obesity, Sleep
Interventions
Not listed
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 22, 2026, 7:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA

NCT02567448
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Sleep and pulmonary physiologic measurements
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Phase 1 Interventional

Seattle-PAP Bubble Nasal CPAP and Work of Breathing

NCT02210026
View directory record Official record
Conditions
Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia, Newborn Primary Sleep Apnea
Interventions
Seattle-PAP
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Hours to 72 Hours
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep Apnea Study in Adults Using DreamPort-Eclipse and a Traditional Nasal Mask

NCT05818540
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Eclipse novel CPAP mask, ResMed P-10 mask
Device
Lead sponsor
Bleep, LLC
Industry
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 22, 2026, 7:59 PM EDT
Completed No phase listed Observational

Direct Referral for Apnea Monitoring

NCT05419323
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
6,501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
San Francisco, California • Portland, Oregon • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 22, 2026, 7:59 PM EDT
Not listed No phase listed Observational

microEEG for Neonatal Apnea, Bradycardia and Desaturation

NCT02436616
View directory record Official record
Conditions
Apnea, Bradycardia, Premature Birth, Seizures
Interventions
microEEG
Device
Lead sponsor
Bio-Signal Group Corp.
Industry
Eligibility
Up to 30 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Oct 22, 2026, 7:59 PM EDT
Completed No phase listed Observational

Extension Study of Original Protocol AERO C009 for Obstructive Sleep Apnea-hypopnea

NCT00849043
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, Obstructive Sleep Apnea, OSAH
Interventions
Not listed
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
13
States / cities
Wallingford, Connecticut • Gainesville, Florida • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2011 · Synced Oct 22, 2026, 7:59 PM EDT
Recruiting Phase 2 Interventional

Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

NCT06521476
View directory record Official record
Conditions
Central Sleep Apnea Comorbid With Opioid Use
Interventions
Acetazolamide, Placebo
Drug
Lead sponsor
Sanjay R Patel
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Not applicable Interventional

Comparison of Mask Ventilation Techniques in Patients Requiring General Anesthesia

NCT02580526
View directory record Official record
Conditions
Apnea
Interventions
V-E mask ventilation for one minute, C-E mask ventilation for one minute
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Phase 3 Interventional Results available

Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea

NCT05412004
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
18
States / cities
Riverside, California • Brandon, Florida • Ocala, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Not applicable Interventional Results available

The Evaluation of a Mask for the Treatment of Obstructive Sleep Apnea

NCT03142438
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
F&P Seal Improvement Project
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Oct 22, 2026, 7:59 PM EDT
Not listed No phase listed Observational

Capnography in the Post-Anesthesia Care Unit (PACU)

NCT03076047
View directory record Official record
Conditions
Obstructive Sleep Apnea, Bariatric Surgery Candidate, Respiratory Insufficiency
Interventions
end-tidal CO2 (ETCO2) monitoring
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 22, 2026, 7:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

SNORE (Smartphone Analyses of Nocturnal Obstruction by Respiratory Evaluation) SOUNDS

NCT03288376
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Chronic Obstructive Pulmonary Disease
Interventions
Not listed
Lead sponsor
Incyphae, Inc.
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Burlingame, California • New London, Connecticut • Lanham, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Not applicable Interventional Results available

Non-Inferiority Study of the FRESCA Mask Versus Existing CPAP Mask for Treatment of Obstructive Sleep Apnea

NCT02387476
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, OSA
Interventions
FRESCA mask first night, CPAP Mask first night
Device
Lead sponsor
FRESCA Medical
Industry
Eligibility
18 Years to 70 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Fresno, California • Murrieta, California • Hollywood, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Oct 22, 2026, 7:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers for Obstructive Sleep Apnea

NCT00834509
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
CPAP
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 70 Years
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Not applicable Interventional

Promoting the Use of CPAP Therapy Among OSA Patients

NCT04372329
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP4HealthySleep system
Behavioral
Lead sponsor
Sarah Alismail
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Claremont, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 22, 2026, 7:59 PM EDT
Not listed Phase 1Phase 2 Interventional

Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy

NCT05550246
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Atomoxetine, Oxybutynin
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Effect of Self-Management on Improving Sleep Apnea Outcomes

NCT00310310
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Sleep Apnea Self-Management Program, Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 22, 2026, 7:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study

NCT01349205
View directory record Official record
Conditions
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Interventions
Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
2 Years to 12 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 22, 2026, 7:59 PM EDT
Terminated Not applicable Interventional Results available

Caffeine to Reduce Mechanical Ventilation in Preterm Infants

NCT01751724
View directory record Official record
Conditions
Prematurity, Apnea, Respiratory Failure
Interventions
Caffeine citrate, Normal saline
Drug · Other
Lead sponsor
University of Miami
Other
Eligibility
1 Day to 5 Days
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Oct 22, 2026, 7:59 PM EDT
Completed Not applicable Interventional

Targeted Hypoglossal Neurostimulation Study #3

NCT02263859
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
aura6000 System
Device
Lead sponsor
ImThera Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
14
States / cities
Chula Vista, California • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 22, 2026, 7:59 PM EDT
Recruiting Not applicable Interventional

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

NCT07220525
View directory record Official record
Conditions
Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction
Interventions
HGNS Use Randomized Instructions
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 22, 2026, 7:59 PM EDT
Withdrawn Not applicable Interventional

Using Continuous Positive Airway Pressure to Reduce the Incidence of Acute Kidney Injury in Hospitalized Patients With Chronic Kidney Disease

NCT01859260
View directory record Official record
Conditions
Chronic Kidney Disease, Obstructive Sleep Apnea
Interventions
CPAP/autopap
Device
Lead sponsor
University of South Florida
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Oct 22, 2026, 7:59 PM EDT