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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:14 PM EST

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Showing 193–216 of 1,578 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Arrhythmias Cardiac Clear all
Not listed Not applicable Interventional

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

NCT05327062
View directory record Official record
Conditions
Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
Interventions
CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment
Device
Lead sponsor
XSpline S.p.A.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Chicago, Illinois • Boston, Massachusetts • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Nov 15, 2026, 1:14 PM EST
Terminated Phase 4 Interventional Results available

Catheter Ablation of Arrhythmias to Improve CRT Response

NCT03035227
View directory record Official record
Conditions
Arrhythmia, Cardiac
Interventions
Catheter Ablation, Anti-Arrhythmics
Procedure · Drug
Lead sponsor
Kansas City Heart Rhythm Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2022 · Synced Nov 15, 2026, 1:14 PM EST
Terminated Phase 3 Interventional Results available

A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke

NCT05643573
View directory record Official record
Conditions
Prevention of Stroke or Systemic Embolism, Atrial Fibrillation
Interventions
Asundexian (BAY2433334), Apixaban, Asundexian matching placebo, Apixaban matching placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
14,830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
163
States / cities
Dothan, Alabama • Fairhope, Alabama • Mobile, Alabama + 144 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional

A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial Fibrillation

NCT00434694
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation (Radiofrequency Catheter Ablation)
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Nov 15, 2026, 1:14 PM EST
Completed No phase listed Observational Accepts healthy volunteers

A Study to Investigate if Early Atrial Fibrillation (AF) Diagnosis Reduces Risk of Events Like Stroke in the Real-World

NCT04276441
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Heart healthy Engagement Program with the Apple Watch Series 5 or later, Anti-Coagulation Adherence Module with the Apple Watch Series 5 or later
Device
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
65 Years and older
Enrollment
34,244 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Nov 15, 2026, 1:14 PM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes

NCT02513940
View directory record Official record
Conditions
Long QT Syndrome
Interventions
Testosterone, Progesterone, Placebo, Ibutilide
Drug
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older · Male only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional

Use of Electronic Personal Health Records to Improve Medication Adherence

NCT03018197
View directory record Official record
Conditions
Atrial Fibrillation, Medication Adherence
Interventions
Medication Education
Other
Lead sponsor
Parkview Health
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Nov 15, 2026, 1:14 PM EST
Active, not recruiting Not applicable Interventional

RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.

NCT05883631
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia
Interventions
Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, Electrographic Flow (EGF) mapping (no ablation)
Device
Lead sponsor
Cortex
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Redwood City, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Nov 15, 2026, 1:14 PM EST
Not listed Phase 2Phase 3 Interventional

Comparison of ATI-5923, a Novel Vitamin K Antagonist, With Warfarin in Patients Requiring Chronic Anticoagulation

NCT00691470
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Venous Thromboembolic Disease, Myocardial Infarction, Cardiomyopathy
Interventions
ATI-5923, Coumadin (warfarin)
Drug
Lead sponsor
ARYx Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
41
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 34 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2010 · Synced Nov 15, 2026, 1:14 PM EST
Recruiting Not applicable Interventional

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

NCT06876896
View directory record Official record
Conditions
Intra-Abdominal Hypertension
Interventions
Accuryn Foley catheter device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Nov 15, 2026, 1:14 PM EST
Completed Phase 3 Interventional

Study of RSD1235 to Evaluate Safety in Patients With Atrial Fibrillation

NCT00281554
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
RSD1235
Drug
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
10
States / cities
Huntsville, Alabama • Atlanta, Georgia • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2008 · Synced Nov 15, 2026, 1:14 PM EST
Completed Phase 3 Interventional

Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects

NCT00126074
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Tedisamil sesquifumarate
Drug
Lead sponsor
Solvay Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
2
States / cities
Honolulu, Hawaii • Tullahoma, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 16, 2015 · Synced Nov 15, 2026, 1:14 PM EST
Recruiting Not applicable Interventional

Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrophysiology Procedures

NCT07806890
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
4D ICE Adjunct Imaging
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional Results available

Ambulatory Post-Syncope Arrhythmia Protection Feasibility Study

NCT02188147
View directory record Official record
Conditions
Syncope
Interventions
Short Term Wearable Defibrillator
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
6
States / cities
Danbury, Connecticut • Jacksonville, Florida • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Nov 15, 2026, 1:14 PM EST
Not listed No phase listed Observational

APPEND-CT Registry

NCT06213285
View directory record Official record
Conditions
Stroke, Ischemic, Device Related Thrombosis, Atrial Fibrillation
Interventions
Watchman FLX left atrial appendage occlusion
Device
Lead sponsor
Aarhus University Hospital
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Timeline
2024 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional Results available

Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation in Subjects With Paroxysmal Atrial Fibrillation

NCT03775512
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
RF Ablation with QDOT Micro
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
22
States / cities
Birmingham, Alabama • Atlantis, Florida • Jacksonville, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional Results available

Intramural Needle Ablation for the Treatment of Refractory Ventricular Arrhythmias

NCT03204981
View directory record Official record
Conditions
Ventricular Arrythmia
Interventions
Intramural Needle Ablation, Ablation
Device · Procedure
Lead sponsor
Vivek Reddy
Other
Eligibility
15 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Nov 15, 2026, 1:14 PM EST
Completed No phase listed Observational

Confirm Rx Insertable Cardiac Monitor SMART Registry

NCT03505801
View directory record Official record
Conditions
Cardiac Arrhythmias, Symptoms and Signs, Atrial Fibrillation
Interventions
Confirm Rx ICM insertion procedure
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Jonesboro, Arkansas • Brandon, Florida • St. Petersburg, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional Results available

Investigational Device Evaluation of the WATCHMAN FLX™ LAA Closure Technology

NCT02702271
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
WATCHMAN FLX
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
29
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Nov 15, 2026, 1:14 PM EST
Terminated Not applicable Interventional Results available

Bispectral Index Monitoring During Testing in the Electrophysiology Lab

NCT00749671
View directory record Official record
Conditions
Tachycardia, Ventricular
Interventions
Bispectral index monitoring, Ramsey Sedation Scale
Device · Other
Lead sponsor
Baystate Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2016 · Synced Nov 15, 2026, 1:14 PM EST
Completed Not applicable Interventional

Pulmonary Vein (PV) Isolation Versus Box Isolation for the Treatment of Atrial Fibrillation

NCT01091597
View directory record Official record
Conditions
Atrial Fibrillation, Radiofrequency Ablation
Interventions
usual PV ablation, Box isolation of pulmonary veins
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Nov 15, 2026, 1:14 PM EST
Completed Phase 3 Interventional Results available

Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)

NCT03310125
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
Interventions
Active Colchicine, Active Placebo
Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
55 Years and older
Enrollment
3,209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
8
States / cities
Weston, Florida • Detroit, Michigan • Stony Brook, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Nov 15, 2026, 1:14 PM EST
Completed Phase 4 Interventional

Smartphones to Improve Rivaroxaban ADHEREnce in Atrial Fibrillation

NCT02996435
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Mobile Application Intervention, No Intervention
Behavioral · Other
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
25
States / cities
Anchorage, Alaska • Los Angeles, California • Manhattan Beach, California + 22 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2018 · Synced Nov 15, 2026, 1:14 PM EST
Not listed No phase listed Observational Accepts healthy volunteers

Artificial Intelligence (AI) Enabled, Cloud-based ECG Diagnostic Solution (ZBPro) Feasibility Testing

NCT06013917
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
Cardiac Monitoring
Device
Lead sponsor
ZBeats INC
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Nov 15, 2026, 1:14 PM EST