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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:26 AM EDT

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Showing 1–24 of 3,644 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Artery Disease Clear all
Completed Not applicable Interventional Results available

JetStream (JS) Atherectomy in Femoropopliteal In-Stent Restenotic Lesions

NCT01722877
View directory record Official record
Conditions
Restenosis, Peripheral Vascular Disease
Interventions
JetStream Navitus
Device
Lead sponsor
Midwest Cardiovascular Research Foundation
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Bettendorf, Iowa • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 29, 2026, 4:26 AM EDT
Completed Phase 1 Interventional Results available

Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso

NCT03950739
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Treprostinil Inhalation Powder
Drug
Lead sponsor
United Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
16
States / cities
Birmingham, Alabama • Los Angeles, California • Jacksonville, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 29, 2026, 4:26 AM EDT
Not yet recruiting No phase listed Observational

Clinical Evaluation of Radiation Reduction for Optimized Safety

NCT06348875
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Infarction, Coronary Disease, Coronary Stenosis, Angina Pectoris, Chest Pain
Interventions
Not listed
Lead sponsor
Angiowave Imaging
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 29, 2026, 4:26 AM EDT
Not yet recruiting Not applicable Interventional

Coronary Artery Calcium (CAC) Testing in Primary Care

NCT07868809
View directory record Official record
Conditions
ASCVD, ASCVD Management, Coronary Artery Calcium, Hyperlipidemia
Interventions
Our Practice Advisory (OPA)
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 29, 2026, 4:26 AM EDT
Withdrawn Phase 3 Interventional

FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

NCT00760916
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
UT-15C 1 mg, UT-15C 0.25 mg, UT-15C 5 mg, Placebo
Drug
Lead sponsor
United Therapeutics
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
26
States / cities
Birmingham, Alabama • Los Angeles, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Oct 29, 2026, 4:26 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults

NCT07143448
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
HS235, Placebo
Biological · Other
Lead sponsor
35Pharma Inc
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Tampa, Florida • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 29, 2026, 4:26 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Heating on Exercise Pressor Reflex in Peripheral Artery Disease: Exercise Ability

NCT03900832
View directory record Official record
Conditions
PAD
Interventions
Without Heating, Warm Bath, Neutral Bath, Heating Suit, Lower limb warm water immersion, Gardner walking protocol
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 29, 2026, 4:26 AM EDT
Completed Not applicable Interventional Results available

A Mobile Health Intervention in Pulmonary Arterial Hypertension

NCT03069716
View directory record Official record
Conditions
Pulmonary Arterial Hypertension, Idiopathic Pulmonary Arterial Hypertension, Heritable Pulmonary Arterial Hypertension, Associated Pulmonary Arterial Hypertension
Interventions
Smartphone Text Messaging, Fitbit Charge HR
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Oct 29, 2026, 4:26 AM EDT
Not listed Not applicable Interventional

Local Delivery of Paclitaxel Via the TAPAS Catheter to Prevent Restenosis From Percutaneous Femoropopliteal Intervention

NCT01599078
View directory record Official record
Conditions
Restenosis, Peripheral Arterial Disease
Interventions
Paclitaxel, Placebo
Drug
Lead sponsor
Midwest Cardiovascular Research Foundation
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Bettendorf, Iowa
Source: ClinicalTrials.gov public record
Updated May 15, 2012 · Synced Oct 29, 2026, 4:26 AM EDT
Not listed Phase 4 Interventional

Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension

NCT01468571
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2015 · Synced Oct 29, 2026, 4:26 AM EDT
Terminated Phase 1 Interventional

Melphalan With BBBD in Treating Patients With Brain Malignancies

NCT00253721
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Lymphoma, Metastatic Cancer
Interventions
Melphalan
Drug
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years to 120 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 29, 2026, 4:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants

NCT00308633
View directory record Official record
Conditions
Coronary Artery Disease (CAD)
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 29, 2026, 4:26 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Reducing Arterial Inflammation Using Eplerenone and Statins in HIV

NCT07892664
View directory record Official record
Conditions
HIV (Human Immunodeficiency Virus), Cardiovascular Diseases (CVD), Arterial Inflammation, Heart Disease
Interventions
Eplerenone, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 80 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
Los Angeles, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 29, 2026, 4:26 AM EDT
Recruiting Not applicable Interventional

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

NCT05994014
View directory record Official record
Conditions
Coronary Artery Disease, Atherosclerosis, Coronary Atherosclerosis of Native Coronary Artery
Interventions
PET/CT
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 29, 2026, 4:26 AM EDT
Recruiting Not applicable Interventional

Repeated Far Infrared Sauna Bathing in Adults With Obesity

NCT07158047
View directory record Official record
Conditions
Obesity (Disorder)
Interventions
Heat therapy
Other
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 29, 2026, 4:26 AM EDT
Recruiting Not applicable Interventional

Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)

NCT07182955
View directory record Official record
Conditions
MINOCA, Shortness of Breath, Atherosclerotic Heart Disease of Native Coronary Artery
Interventions
EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 29, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Efficacy of Prostatic Artery Embolization (PAE) in Patients With Severe Benign Prostatic Hyperplasia (BPH)

NCT02167919
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
Microspheres
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Oct 29, 2026, 4:26 AM EDT
Completed No phase listed Observational

Radial Versus Femoral Arterial Access for Cardiac Catheterization: Comparison of Complications at 30 Days

NCT01019330
View directory record Official record
Conditions
Radial Artery Occlusion
Interventions
Allen's test, Distal pulses
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years and older
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 30, 2015 · Synced Oct 29, 2026, 4:26 AM EDT
Withdrawn Phase 4 Interventional

Efficacy of Ranolazine in Patients With Chronic Total Occlusions of Coronary Arteries

NCT02423265
View directory record Official record
Conditions
Myocardial Ischemia, Coronary Artery Disease, Arteriosclerosis, Chronic Stable Angina
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
East Carolina University
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Oct 29, 2026, 4:26 AM EDT
Active, not recruiting Not applicable Interventional

A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD

NCT06713239
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Cleerly Labs and Cleerly ISCHEMIA
Device
Lead sponsor
Cleerly, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
21
States / cities
Mobile, Alabama • Huntington Park, California • San Diego, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 29, 2026, 4:26 AM EDT
Completed Not applicable Interventional Results available

The Complete® Self-Expanding Stent and Stent Delivery System Registry

NCT00730730
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Complete SE Iliac Stent
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Flint, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Oct 29, 2026, 4:26 AM EDT
Terminated Phase 2 Interventional Results available

Intra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma

NCT01293539
View directory record Official record
Conditions
Retinoblastoma
Interventions
Melphalan hydrochloride
Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
Up to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 27, 2018 · Synced Oct 29, 2026, 4:26 AM EDT
Withdrawn Not applicable Interventional

Comparing Perclose to Statseal in Conjunction With Perclose in Femoral 6 French Arteriotomy Closure

NCT05468957
View directory record Official record
Conditions
Arterial Occlusion, Cardiovascular Diseases, Atherosclerosis, Hematoma
Interventions
Perclose, Statseal
Device · Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 29, 2026, 4:26 AM EDT
Active, not recruiting No phase listed Observational

Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women

NCT04599192
View directory record Official record
Conditions
Coronary Disease, Percutaneous Coronary Intervention, Exercise Test, Myocardial Perfusion Imaging, Cardiac Catheterization
Interventions
No study intervention
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 29, 2026, 4:26 AM EDT