Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:26 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Knee Osteoarthritis
Interventions: periosteal electrical dry needling with no maintenance treatments, periosteal electrical dry needling with maintenance treatments every other month, periosteal electrical dry needling with monthly maintenance treatments; Other
Lead sponsor: Alabama Physical Therapy & Acupuncture; Other
Eligibility: 18 Years and older
Enrollment: 586 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Chamblee, Georgia

Conditions: Osteoarthritis, Knee
Interventions: Q-Factor Intervention; Procedure
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 50 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Knee Osteoarthritis, Arthritis Knee
Interventions: ZYNRELEF 400Mg-12Mg Extended-Release Solution, Ultrasound-Guided Adductor Canal Block, Ropivacaine 0.5% Injectable Solution; Drug · Procedure
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Osteoarthritis, Total Knee Arthroplasty, Stability, Knee Osteoarthritis
Interventions: Stress X-Ray; Other
Lead sponsor: David F. Scott, MD; Other
Eligibility: 21 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Osteoarthritis of the Knee
Interventions: iTotal G2 CR Knee Replacement System; Device
Lead sponsor: Restor3D; Industry
Eligibility: 18 Years and older
Enrollment: 359 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2023
U.S. locations: 9
States / cities: Atlantis, Florida • Bangor, Maine • Battle Creek, Michigan + 6 more

Conditions: Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
Interventions: Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction; Biological · Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Atlanta, Georgia • New York, New York

Conditions: Shoulder Disease, Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions: Time of Sling Use; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Muscle Atrophy
Interventions: IMM01-STEM; Drug
Lead sponsor: Immunis, Inc.; Industry
Eligibility: 50 Years to 75 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Irvine, California • Orange, California

Conditions: Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Ankle
Interventions: Group Physical Therapy Classes; Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2030
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions: Fasinumab, Diclofenac, Celecoxib, Matching placebo; Drug · Other
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 1,650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 71
States / cities: Anniston, Alabama • Mobile, Alabama • Chandler, Arizona + 63 more

Conditions: Osteoarthritis (OA) of the Hip
Interventions: Total hip arthroplasty via direct anterior approach (manual, non-robotic), Total hip arthroplasty via posterior approach (manual, non-robotic), Robotic-assisted total hip arthroplasty via posterior approach; Procedure
Lead sponsor: Ochsner Health System; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Metairie, Louisiana • New Orleans, Louisiana

Conditions: Osteoarthritis, Knee
Interventions: Navio™ Robotics-assisted Surgical System; Device
Lead sponsor: Columbia University; Other
Eligibility: 40 Years to 85 Years
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Osteoarthritis
Interventions: hydrocodone / acetaminophen extended release, Placebo; Drug
Lead sponsor: Abbott; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 873 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 83
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 68 more

Conditions: Osteoarthritis, Knee
Interventions: MobilWise, Fitbit Only; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Pain, Osteoarthritis of the Knee
Interventions: Buprenorphine, Placebo; Drug
Lead sponsor: Purdue Pharma LP; Industry
Eligibility: 40 Years and older
Enrollment: 567 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 87
States / cities: Mobile, Alabama • Chandler, Arizona • Phoenix, Arizona + 73 more

Conditions: Knee Osteoarthritis
Interventions: Liposomal bupivacaine, Ropivacaine, Epinephrine, Clonidine, Saline; Drug
Lead sponsor: The Hawkins Foundation; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Total Shoulder Arthroplasty, Glenohumeral Osteoarthritis
Interventions: Not listed
Lead sponsor: Western Orthopaedics Research and Education Foundation; Other
Eligibility: 21 Years to 90 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Osteoarthritis, Knee
Interventions: EUFLEXXA™, placebo; Device
Lead sponsor: Ferring Pharmaceuticals; Industry
Eligibility: 40 Years and older
Enrollment: 588 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Osteoarthritis
Interventions: synovial fluid biomarker concentrations; Biological
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 90 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Hip Arthrosis, Osteoarthritis, Arthritis
Interventions: Capsulectomy in Direct Anterior Total Hip Arthroplasty, Capsulotomy in Direct Anterior Total Hip Arthroplasty; Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Lower-limb Orthoses, Osteoarthritic Knee Pain, Osteoarthritis (OA) of the Knee
Interventions: Modular powered orthosis; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 85 Years
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions: casts for the thumb, Motion group; Other
Lead sponsor: University of Utah; Other
Eligibility: 40 Years to 80 Years
Enrollment: 234 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Knee Osteoarthritis (OA)
Interventions: Collagen Hydrolysate, Placebo; Dietary Supplement
Lead sponsor: GELITA; Industry
Eligibility: 49 Years to 90 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease, Amyloidosis, Ankylosing Spondylitis, Arthritis, Alopecia Areata, Asthma, Atopic Dermatitis, Autism, Autoimmune Hepatitis, Behcet's Disease, Beta-Thalassemia, Cancer, Celiac Disease, Kidney Diseases, COPD, Crohn Disease, Cystic Fibrosis, Diabetes, Dravet Syndrome, DMD, Fibromyalgia, Graves Disease, Thyroid Diseases, Hepatitis, Hidradenitis Suppurativa, ITP, Leukemia, ALS, Lupus or SLE, Lymphoma, Multiple Sclerosis, Myasthenia Gravis, Heart Diseases, Parkinson Disease, Pemphigus Vulgaris, Cirrhosis, Psoriasis, Schizophrenia, Scleroderma, Sickle Cell Disease, Stroke, Ulcerative Colitis, Vasculitis, Vitiligo
Interventions: Specimen sample; Diagnostic Test
Lead sponsor: Sanguine Biosciences; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 20,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Waltham, Massachusetts

Search by objective public record fields.

Periosteal Electrical Dry Needling for Knee Osteoarthritis

Cycling Intervention on Symptoms of Patients With Knee Osteoarthritis

Zynrelef Versus Adductor Canal Block

Antero-Posterior Knee Stability

A Prospective, Multicenter Study to Evaluate the ConforMIS iTotal® (CR) Knee Replacement System

Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction

Sling vs No Sling After Reverse Total Shoulder Arthroplasty

Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

Outcomes of Low-Impact Exercise Program for People With Ankle, Knee, and/or Hip Pain

Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip

Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior

Navio Robotic Versus Conventional Total Knee Arthroplasty

A Study of Pain Relief in Osteoarthritis

MobilWise: Mobile Phone Remote Coaching After Worksite Joint ADventure Exposure

Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee

Exparel vs Exparel Plus ACB in TKAs

A Retrospective Review of FloSeal Use in Total Shoulder Arthroplasty

A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee

Reduction of Pro-Inflammatory Synovial Fluid Biomarkers in Osteoarthritis of the Knee With Alpha-2 Macroglobulin

Capsulectomy vs Capsulotomy With Repair in Direct Anterior Total Hip Arthroplasty

Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal

Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition

A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA)

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives