Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:57 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Knee Osteoarthritis
Interventions: Tai Chi, Physical Therapy; Behavioral
Lead sponsor: Tufts Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis of the Knee
Interventions: Instrument; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Osteoarthritis
Interventions: functional exercise training; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 50 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Osteoarthritis, Knee
Interventions: High-dose/short-duration Fisetin, Low-dose/sustained-duration Fisetin, Oral placebo capsule; Drug · Other
Lead sponsor: Austin V Stone; Other
Eligibility: 35 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Lexington, Kentucky

Conditions: Osteoarthritis
Interventions: Adipose Derived (AD) Stromal Vascular Fraction (SVF); Genetic
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 45 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Osteoarthritis, Knee
Interventions: Positive Minds, Strong Joints; Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 50 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Arthritis, Rheumatoid, Arthritis, Psoriatic
Interventions: Naltrexone, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Knee Osteoarthritis
Interventions: Micronized dHACM, Saline; Biological · Drug
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 447 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 17
States / cities: Birmingham, Alabama • Tempe, Arizona • La Mesa, California + 14 more

Conditions: Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity, Knee Pain Chronic
Interventions: Persona Partial Knee System; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2030
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Back Pain Lower Back Chronic, Chronic Pain, Musculoskeletal Pain
Interventions: Digital Musculoskeletal (MSK) Program, Transcutaneous Electrical Nerve Stimulation (TENS), Standard of Care (SOC); Behavioral · Device · Other
Lead sponsor: Hinge Health, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Eden Prairie, Minnesota

Conditions: Total Knee Arthroplasty, Osteoarthritis
Interventions: Physical Activity Behavior Intervention, Attention Control; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 85 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Osteoarthritis
Interventions: Jebsen Taylor Hand function test, Pinch strength, Grooved pegboard test; Diagnostic Test
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Knee Osteoarthritis
Interventions: Strength Training; Other
Lead sponsor: Frederiksberg University Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: 40 Years to 90 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Osteoarthritis, Knee, Knee Pain Chronic
Interventions: Progressive Walking with Gait Retraining, Progressive Walking Program; Behavioral
Lead sponsor: Northeastern University; Other
Eligibility: 45 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder, Pain, Chronic, Tendonitis Elbow, Tendonitis Shoulder, Tendonitis;Achilles, Tenosynovitis
Interventions: Artery Embolization; Procedure
Lead sponsor: Vascular Solutions of North Carolina; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: Cary, North Carolina • Winchester, Tennessee

Conditions: Osteoarthritis, Rheumatoid Arthritis, Arthritis, Avascular Necrosis, Acute Fracture
Interventions: Acetabular cup; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: Not listed
Enrollment: 1,593 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2012
U.S. locations: 1
States / cities: Warsaw, Indiana

Conditions: Osteoarthritis, Knee
Interventions: Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW), Numerical pain scale, Self-assessed function, Muscle biopsies, Determination of 1 Repetition Maximum (1-RM), Blood flow restriction exercise, Borg CR10 scale; Device · Behavioral · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 55 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Thumb Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
Interventions: Dynamic Stability Exercise Program; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis, Correction of Functional Deformity, Fracture of the Humeral Head, Traumatic Arthritis, Revision of the Devices if Sufficient Bone Stock Remains
Interventions: Tornier Perform™ Reversed MonoPost; Device
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 2
States / cities: Rancho Mirage, California • Columbus, Ohio

Conditions: Osteoarthritis, Knee
Interventions: UBX0101, Placebo; Drug · Other
Lead sponsor: Unity Biotechnology, Inc.; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 7
States / cities: El Cajon, California • La Mesa, California • Miami, Florida + 4 more

Conditions: Post-Meniscectomy Pain Syndrome, Osteoarthritis, Knee
Interventions: NUsurface® Meniscus Implant; Device
Lead sponsor: Phoenix Kinetics; Industry
Eligibility: 30 Years to 75 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 13
States / cities: Phoenix, Arizona • La Mesa, California • Long Beach, California + 10 more

Conditions: Osteoarthritis of the Knee
Interventions: Cooled Radiofrequency, Hyaluronic Acid Injection, Crossover from Hyaluronic Acid Injection to Cooled Radiofrequency; Device · Other
Lead sponsor: Avanos Medical; Other
Eligibility: 21 Years and older
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 10
States / cities: Coeur d'Alene, Idaho • New Orleans, Louisiana • Rochester, Minnesota + 7 more

Conditions: Knee Osteoarthritis
Interventions: iovera°, Sham Comparator; Device
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 35 Years to 75 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 17
States / cities: Covina, California • Sacramento, California • Bradenton, Florida + 14 more

Search by objective public record fields.

Tai Chi and Physical Therapy for Knee Osteoarthritis

A Randomized Prospective Trial of Total Knee Arthroplasty Options Comparing Standard Knee Cutting Guides and MRI Generated Patient Specific Custom Cutting Guides

Exercise Intervention to Reduce Postural Instability in Osteoarthritis

Targeting Senescence to Reduce Osteoarthritis Pain and cartilagE Breakdown (ROPE)

Stromal Vascular Fraction (SVF) for Knee Post-Trauma Osteoarthritis (PTOA)

Positive Minds Strong Joints for Knee Osteoarthritis

Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis

Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee

A Randomized Controlled Trial for Partial Knee Arthroplasty

Examining the Impact of a Digital Health Program and TENS Device for Patients With Chronic Low Back Pain

Optimizing Physical Activity Outcomes After Total Knee Arthroplasty

Function Following Thumb MP Fusion and IP Fusion

Strengthening Exercise and Quadriceps Force During Walking

Outcomes Following Total Knee Arthroplasty

Effectiveness of a Walking Intervention on Impact Loading and Pain

Embo Registry; National Registry for Artery Embolization

Clinical Study Evaluating an Acetabular Cup System After Total Hip Replacement

Blood Flow Restriction Exercise Study

Mechanisms of a Dynamic Stability Approach

Tornier Perform™ Reversed Monopost Study

A Safety and Tolerability Study of UBX0101 in Patients With Osteoarthritis of the Knee

The SUN Clinical Trial (Safety Utilizing NUsurface Meniscus Implant)

Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain