- Conditions
- Lower-limb Orthoses, Osteoarthritic Knee Pain, Osteoarthritis (OA) of the Knee
- Interventions
- Modular powered orthosis
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
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All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 969
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain, Knee Extension
- Interventions
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Drug · Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Anesthesia Morbidity, Osteoarthritis, Knee, Osteoarthritis, Hip
- Interventions
- Anesthesia Type
- Procedure
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12,466 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- South San Francisco, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- TLC599, DSP, Normal Saline
- Drug · Other
- Lead sponsor
- Taiwan Liposome Company
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 504 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 41
- States / cities
- Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 33 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Exercise Cycle, Land-based Treadmill, Water-based Treadmill
- Behavioral
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 30 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Knee Osteoarthritis
- Interventions
- Synvisc-One Injection, Sham Injection
- Device · Other
- Lead sponsor
- Elaine Husni
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Weston, Florida
- Conditions
- Osteoarthritis, Knee
- Interventions
- Celecoxib, Placebo
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 380 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2004
- U.S. locations
- 30
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Long Beach, California + 27 more
- Conditions
- Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus, Flexion Deformities
- Interventions
- NexGen LPS-Flex Mobile Bearing Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Enrollment
- 266 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2021
- U.S. locations
- 3
- States / cities
- Tamarac, Florida • Auburn Hills, Michigan • Knoxville, Tennessee
- Conditions
- Osteoarthritis (OA) of the Knee, Fear of Needles
- Interventions
- 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
- Procedure
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 40 Years to 89 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Osteoarthritis, Pain, Postoperative
- Interventions
- Liposomal bupivacaine, Bupivacaine plus dexamethasone
- Drug
- Lead sponsor
- Albany Medical College
- Other
- Eligibility
- 40 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Albany, New York
- Conditions
- Knee Osteoarthritis
- Interventions
- Optimized Tai Chi intervention, Traditional Tai Chi intervention
- Behavioral
- Lead sponsor
- Edward Via Virginia College of Osteopathic Medicine
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Osteoarthritis, Knee
- Interventions
- Hyaluronic Acid, Amniotic Tissue Allograft, Saline
- Device · Drug
- Lead sponsor
- The Stone Research Foundation for Sports Medicine and Arthritis
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Chondral Lesion of the Knee, Meniscal Injuries, Cartilage Defects of the Knee, Osteoarthritis (OA) of the Knee
- Interventions
- Bone Marrow Aspirate (BMA), Arthroscopic Debridement Surgery, Saline
- Biological · Procedure · Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Knee Osteoarthritis
- Interventions
- Orthovisc, DonJoy HA lite knee brace, Orthovisc injections and DonJoy HA lite knee brace
- Other · Device
- Lead sponsor
- OAD Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Warrenville, Illinois
- Conditions
- Rupture of Anterior Cruciate Ligament, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 14 Years to 55 Years
- Enrollment
- 432 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2025
- U.S. locations
- 4
- States / cities
- St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Cannabidiol (CBD) Extract, Placebo
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Total Knee Arthroplasty
- Interventions
- Journey II BCS Total Knee System
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 1,694 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 9
- States / cities
- Aurora, Colorado • Gulf Breeze, Florida • Indianapolis, Indiana + 6 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Lidoderm, Placebo patch
- Drug
- Lead sponsor
- Endo USA Inc., a Keenova Therapeutics Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 224 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2004
- U.S. locations
- 24
- States / cities
- Birmingham, Alabama • Hueytown, Alabama • Tallassee, Alabama + 21 more
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Interventions
- Maxim® Knee System with Removable Molded Polyethylene Tibia, Regular Maxim® Knee System
- Device
- Lead sponsor
- Biomet Orthopedics, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Warsaw, Indiana
- Conditions
- Degenerative Arthritis
- Interventions
- Orthosensor™ VERASENSE™ Knee System
- Device
- Lead sponsor
- LifeBridge Health
- Other
- Eligibility
- 45 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Osteo Arthritis Knee, Total Knee Replacement
- Interventions
- Total Knee Arthroplasty using LEGION™ Total Knee System
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2020
- U.S. locations
- 5
- States / cities
- Vero Beach, Florida • Des Moines, Iowa • Louisville, Kentucky + 2 more
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Interventions
- Liposomal bupivacaine, 266mg, Bupivacaine 0.5 % with Epinephrine, Ketorolac 30mg, Morphine 10mg, Bupivacaine 0.25% with Epinephrine
- Drug
- Lead sponsor
- Holy Cross Hospital, Florida
- Other
- Eligibility
- 18 Years to 88 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fort Lauderdale, Florida
- Conditions
- Osteoarthritis Of Knee
- Interventions
- Geniculate Artery Embolization
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Woodbridge, Virginia
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder, Pain, Loss of Function
- Interventions
- Not listed
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- San Bernardino, California