- Conditions
- Post-operative Pain
- Interventions
- 15mL 0.25% bupivacaine, Genicular nerve block, Saline
- Drug · Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 313–336
of 843
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Arthropathy of Knee, Obesity
- Interventions
- Multi-Component Weight Loss Intervention
- Behavioral
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Osteoarthritis
- Interventions
- Evicel fibrin sealant
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 20 Years to 90 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis
- Interventions
- Total and Unicompartment Knee Replacement
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Leesburg, Florida
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- Neuromuscular electrical stimulation, Voluntary exercise
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 45 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Knee Arthroplasty
- Interventions
- NEAT!2, MyKneeGuide
- Behavioral
- Lead sponsor
- University of South Carolina
- Other
- Eligibility
- 40 Years to 79 Years
- Enrollment
- 83 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Osteoarthritis, Knee
- Interventions
- iTotal PS Knee Replacement System, Off-the-Shelf Knee Replacement System
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Post-Operative Pain Management
- Interventions
- ioveraº, ioveraº sham
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 7
- States / cities
- Fremont, California • Pasadena, California • Tamarac, Florida + 4 more
- Conditions
- Arthroplasty Replacement Knee, Knee Prosthesis
- Interventions
- Subjects implanted with DePuy LCS PS RP TKA, Subjects implanted with DePuy Sigma PS RP TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 4
- States / cities
- Denver, Colorado • Knoxville, Tennessee
- Conditions
- Total Knee Arthroplasty
- Interventions
- InterACTION, Standard of Care Physical Therapy
- Device · Other
- Lead sponsor
- James J. Irrgang
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Arthritis of the Knee
- Interventions
- iovera°, iovera° Sham
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 22 Years to 79 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 8
- States / cities
- San Diego, California • Englewood, Colorado • Fort Lauderdale, Florida + 5 more
- Conditions
- Total Knee Replacement, Genicular Nerve Block, Opioid Use
- Interventions
- Bupivacaine Injection, Dexamethasone injection, Fentanyl, Mepivacaine
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Posterior Knee Infiltration
- Interventions
- Ropivacaine with Epinephrine, Ropivacaine
- Drug
- Lead sponsor
- Trinity Health Of New England
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Hartford, Connecticut
- Conditions
- Total Knee Arthroplasty
- Interventions
- Intraosseous Vamcomycin Administration
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Pain, Postoperative, Arthroplasty Complications
- Interventions
- Ketamine
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block
- Interventions
- Automated intermittent bolus
- Other
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Arthropathy of Knee Joint
- Interventions
- Weight-bearing biofeedback exercise, Standard of care exercise
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Arthropathy of Knee Joint
- Interventions
- CyMedica Orthopedics QB1 e-vive™ system
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Knee Prosthesis, Knee Replacement Arthroplasty
- Interventions
- Sigma Posterior Stabilizing Rotating Platform TKA Beaded Poly
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 3
- States / cities
- Denver, Colorado • Knoxville, Tennessee
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
- Interventions
- MOTO Medial® UKA
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 269 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2025
- U.S. locations
- 5
- States / cities
- Lady Lake, Florida • Louisville, Kentucky • Billings, Montana + 2 more
- Conditions
- Total Knee Arthroplasty
- Interventions
- Methylprednisolone, Placebo
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Interventions
- Liposomal bupivacaine, 266mg, Bupivacaine 0.5 % with Epinephrine, Ketorolac 30mg, Morphine 10mg, Bupivacaine 0.25% with Epinephrine
- Drug
- Lead sponsor
- Holy Cross Hospital, Florida
- Other
- Eligibility
- 18 Years to 88 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fort Lauderdale, Florida
- Conditions
- Postoperative Pain, Total Knee Replacement, Total Knee Arthroplasty, Partial Knee Replacement
- Interventions
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Device
- Lead sponsor
- SPR Therapeutics, Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 10
- States / cities
- Little Rock, Arkansas • San Diego, California • Gainesville, Florida + 7 more
- Conditions
- Arthroplasties, Knee Replacement
- Interventions
- Depuy total knee implant, Triathlon total knee implant
- Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- St Louis, Missouri