- Conditions
- Total Knee Replacement
- Interventions
- CPM, GAPFLEX
- Device
- Lead sponsor
- Xeras Medical Technologies
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 2
- States / cities
- San Antonio, Texas
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 601–624
of 843
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Total Knee Replacement, Total Knee Arthroplasty, Pain, Postoperative Pain, Orthopedic Disorder
- Interventions
- SPRINT Beta System
- Device
- Lead sponsor
- SPR Therapeutics, Inc.
- Industry
- Eligibility
- 21 Years to 90 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 5
- States / cities
- La Jolla, California • Durham, North Carolina • Cleveland, Ohio + 2 more
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon® CR Total Knee System
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 419 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2017
- U.S. locations
- 11
- States / cities
- Phoenix, Arizona • Miami, Florida • Columbus, Georgia + 8 more
- Conditions
- Osteoarthritis of the Knee
- Interventions
- t-RFA, C-RFA, Control
- Procedure
- Lead sponsor
- Lyman Medical Research Foundation, Inc.
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- Coeur d'Alene, Idaho • Spokane, Washington
- Conditions
- Osteoarthritis, Postoperative Pain
- Interventions
- pregabalin, Placebo
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 307 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 27
- States / cities
- Northport, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 21 more
- Conditions
- Knee Osteoarthritis
- Interventions
- SOLUGEL, Placebo
- Dietary Supplement
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Total Knee Arthroplasty
- Interventions
- Methylprednisolone, Placebo
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 420 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Oak Brook, Illinois
- Conditions
- Pain, Postoperative, Satisfaction
- Interventions
- Ropivacaine
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 164 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- Neuromuscular electrical stimulation, Voluntary exercise
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 45 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Postsurgical Pain
- Interventions
- AYX1 Injection 660 mg / 6 mL, AYX1 Injection 1100 mg / 10 mL, Placebo Injection 6 mL, Placebo Injection 10 mL
- Drug
- Lead sponsor
- Adynxx, Inc.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 2
- States / cities
- Sheffield, Alabama • Phoenix, Arizona
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- CORI™ KNEE TENSIONER
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- New York, New York • New Albany, Ohio • Pittsburgh, Pennsylvania + 1 more
- Conditions
- Osteoarthritis
- Interventions
- Home PT via web-based platform, Home PT via paper manual, outpatient PT
- Other
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Arthroplasty, Knee Pain
- Interventions
- 0.1% and 0.4% perineural ropivicaine
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Osteoarthritis of Knee
- Interventions
- Medacta GMK Sphere
- Device
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Knee, Osteoarthritis Knees Both, Joint Inflammation
- Interventions
- Astaxanthin, Placebo
- Drug · Other
- Lead sponsor
- Prisma Health-Midlands
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Knee Injuries, Knee Osteoarthritis, Knee Arthritis
- Interventions
- B-FREE
- Other
- Lead sponsor
- Michigan Technological University
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- Houghton, Michigan
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative
- Interventions
- Genetic Panel for Analgesics
- Genetic
- Lead sponsor
- TriHealth Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Zip Surgical Skin Closure, Steel Staples
- Device
- Lead sponsor
- ZipLine Medical Inc.
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
- Interventions
- PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more
- Conditions
- Post-Operative Pain, Total Knee Arthroplasty
- Interventions
- Total knee arthroplasty (TKA), Cryoablation
- Procedure · Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 215 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Knee Injuries, Knee Injuries and Disorders, Opioid Use
- Interventions
- Opioid Reduction Program
- Behavioral
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Knee Arthroplasty, Total
- Interventions
- Truliant Total Knee System
- Device
- Lead sponsor
- Exactech
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2035
- U.S. locations
- 5
- States / cities
- Aurora, Colorado • DeLand, Florida • Las Vegas, Nevada + 2 more
- Conditions
- Revision Total Knee Arthroplasty
- Interventions
- ATTUNE Revision Knee System in Revision Total Knee Arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2029
- U.S. locations
- 16
- States / cities
- San Diego, California • Denver, Colorado • Fort Collins, Colorado + 13 more
- Conditions
- Total Knee Arthoplasty
- Interventions
- total knee arthroplasty, Tobramycin, Gentamicin, Antibiotic cement spacer
- Procedure · Drug · Device
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania