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Showing 793–816 of 845 matching trials from the live ClinicalTrials.gov search.
Conditions
Arthritis
Interventions
Vitagel
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Osteoarthritis
Interventions
Fixed Bearing or Mobile Bearing UKA
Device
Lead sponsor
Medacta USA
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Leesburg, Florida
Not listed Not applicable Interventional

Home PT vs FORCE PT

NCT02911389
Conditions
Osteoarthritis
Interventions
Home PT via web-based platform, Home PT via paper manual, outpatient PT
Other
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Difference Between Femoral Nerve Block and Saphenous Block
Interventions
Study Technique, Control Technique
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
40 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Arthritis Knee, Postoperative Nausea, Postoperative Pain
Interventions
Dexamethasone, Placebo
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Grosse Pointe Farms, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Heat Application to Quadriceps Effect on Pain After a Total Knee Arthroplasty

NCT05462483
Conditions
Arthritis Knee
Interventions
Rice Sock and Instructions to heat the quadriceps.
Other
Lead sponsor
The Idaho Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boise, Idaho
Terminated No phase listed Observational

The Knee Usual Care Evaluation Study

NCT01905358
Conditions
Knee Osteoarthritis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
30 Years to 80 Years
Enrollment
906 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Knee Osteoarthritis
Interventions
VERASENSE
Procedure
Lead sponsor
Orthosensor, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Study of Incision Closure Methods for Total Knee Replacement

NCT01088074
Conditions
Total Knee Replacement Closure, Wound Closure
Interventions
Histoacryl Tissue Adhesive, Dermabond, Staples, Monocryl 4-0
Device
Lead sponsor
Foundation for Southwest Orthopedic Research
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation

NCT00760383
Conditions
Osteoarthritis
Interventions
Essential amino acids, Alanine
Dietary Supplement
Lead sponsor
University of Oregon
Other
Eligibility
60 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
2
States / cities
Eugene, Oregon
Completed Not applicable Interventional Results available

Acupuncture for Low-Dose Opioid for TKA Replacement

NCT04084288
Conditions
Knee Osteoarthritis, Pain, Postoperative, Acupuncture
Interventions
Acupuncture, Peripheral Nerve Stimulator
Other · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers

Intra-Venous Acetaminophen and Muscle Relaxants After Total Knee

NCT02449369
Conditions
Unilateral Knee Arthroplasty
Interventions
Preop acetaminophen IV, Preop orphenadrine IV, Postop oral oxycodone & acetaminophen, Postop hydromorphone IV, Postop oral orphenadrine, Postop oral oxycodone, Postop acetaminophen IV, Postop orphenadrine IV
Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Winter Park, Florida
Conditions
Total Knee Arthroplasty
Interventions
HTX-011, ropivacaine , epinephrine , ketorolac diluted in sodium chloride
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Pain, Postoperative, Osteo Arthritis Knee
Interventions
Exparel
Drug
Lead sponsor
Campbell Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Germantown, Tennessee
Conditions
Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Implant, Knee Injuries
Interventions
Klassic Knee System
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Hip Fracture, Osteoarthritis, Femur Head Necrosis
Interventions
Essential amino acid supplement, Ketoconazole, Placebo
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA

NCT04814992
Conditions
Chronic Post-Surgical Pain
Interventions
Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
4
States / cities
Philadelphia, Pennsylvania • Radnor, Pennsylvania
Completed Phase 4 Interventional Results available

Pre vs Post Block in Total Knee Arthroplasty (TKA)

NCT05974501
Conditions
Knee Osteoarthritis, Arthroplasty Complications, Postoperative Pain
Interventions
Dexamethasone, Acetaminophen, Lyrica, Celebrex, Meloxicam, Oxycodone, Ropivacaine
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Miami, Florida
Completed No phase listed Observational

Antero-Posterior Knee Stability

NCT03387839
Conditions
Osteoarthritis, Total Knee Arthroplasty, Stability, Knee Osteoarthritis
Interventions
Stress X-Ray
Other
Lead sponsor
David F. Scott, MD
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Spokane, Washington
Completed No phase listed Observational Results available

Pain and Function After Orthopedic Surgery

NCT01390298
Conditions
Chronic Pain
Interventions
Observational
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Arthroplasty, Replacement, Knee, Thromboembolism
Interventions
Dabigatran Dose 1 - day 2 to completion, Dabigatran Dose 1 - day 1, Dabigatran Dose 2 - day 2 to completion, Dabigatran Dose 2 - day 1, Enoxaparin
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
2,615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
59
States / cities
Birmingham, Alabama • Northport, Alabama • Tucson, Arizona + 48 more
Not listed No phase listed Observational

C3 Total Joint Patient Registry

NCT02188199
Conditions
Knee Replacement, Hip Replacement
Interventions
Not listed
Lead sponsor
DC2 Healthcare
Industry
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Degenerative Joint Disease, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
Interventions
3DKnee™ System
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
8
States / cities
Scottsdale, Arizona • Fresno, California • Baltimore, Maryland + 5 more
Completed No phase listed Observational Accepts healthy volunteers

Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty

NCT04166539
Conditions
Metallosis, Pain, Total Hip Replacement, Total Knee Replacement
Interventions
Questionnaires, Interviews, Blood draw, Magnetic Resonance Imaging, Echocardiogram
Behavioral · Other · Radiation + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota