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ClinicalTrials.gov public records Last synced Sep 30, 2026, 7:49 PM EDT

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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: At Risk for Type 2 Diabetes Mellitus Clear all
Not yet recruiting Not applicable Interventional

South Asians With Type 2 Diabetes at Risk for Depression

NCT07219667
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
CHW-led T2D Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Post-prandial Effects of Extra Virgin Olive Oil on Endothelial Function in Adults at Risk for Type 2 Diabetes

NCT04025281
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Extra Virgin Olive Oil, Refined Olive Oil
Other
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 30, 2026, 7:49 PM EDT
Recruiting Phase 2 Interventional

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

NCT07783802
View directory record Official record
Conditions
Atherosclerosis, Cardiovascular Disease, Obesity, Hypertension, Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic
Interventions
Clazakizumab, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
30
States / cities
Huntsville, Alabama • Tucson, Arizona • Glendora, California + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Active, not recruiting Early Phase 1 Interventional

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

NCT06190158
View directory record Official record
Conditions
Type 2 Diabetes, Chronic Kidney Diseases
Interventions
Oral sodium suppression test, Saline suppression test, Captopril suppression test, Dexamethasone suppression test, Cosyntropin stimulation test
Diagnostic Test
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Fos Biomedical Device on Diabetes Risk Factors and Sleep Quality in Adults at Risk for Type 2 Diabetes

NCT05628597
View directory record Official record
Conditions
Pre Diabetes
Interventions
Fos Biomedical patch product, Fos Biomedical patch product:placebo
Device
Lead sponsor
Griffin Hospital
Other
Eligibility
40 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 30, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional

Heat and Exercise in Aging as Therapy (HEAT)

NCT06580964
View directory record Official record
Conditions
Prediabetic State
Interventions
Heat therapy, High-intensity interval training
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
50 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed No phase listed Observational Results available

Improving Screening and Therapy for Hispanic/Latinx at Risk for CKD

NCT05734989
View directory record Official record
Conditions
Type 2 Diabetes, Chronic Kidney Diseases
Interventions
BP, HbA1c, PCP Guidelines for Screening and Monitoring Hispanic/Latinx patients for CKD
Diagnostic Test · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Recruiting Early Phase 1 Interventional

Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes

NCT05041491
View directory record Official record
Conditions
Pre-diabetes
Interventions
BREAK, ONE
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MapTrek to Increase Activity Among Patients at Risk for Type 2 Diabetes

NCT03193229
View directory record Official record
Conditions
Pre Diabetes, Obesity
Interventions
MapTrek, Fitbit
Behavioral · Device
Lead sponsor
Philip Polgreen
Other
Eligibility
21 Years to 80 Years
Enrollment
430 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Coralville, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Mood and Insulin Resistance in Adolescents At-Risk for Diabetes

NCT01425905
View directory record Official record
Conditions
Depression, Impaired Glucose Tolerance
Interventions
The Blues Program, Hey Durham
Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
12 Years to 17 Years · Female only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 30, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

NCT05543083
View directory record Official record
Conditions
Insulin Resistance, Depression, Depressive Disorder, Mood Disorders, Mental Disorder in Adolescence, Hyperinsulinism, Glucose Metabolism Disorders, Metabolic Disease
Interventions
Cognitive-Behavioral Therapy followed by Exercise Training, Exercise Training followed by Cognitive-Behavioral Therapy, Cognitive-Behavioral Therapy Only, Exercise Training Only
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Type 2 Diabetes Primary Prevention for At Risk Girls

NCT00063674
View directory record Official record
Conditions
Obesity, Diabetes Mellitus, Pre Diabetes
Interventions
Nutrition Education, After-school dance class
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 10 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional

PACE-iDP: An Intervention for Youth at Risk for Diabetes

NCT00412165
View directory record Official record
Conditions
Obesity, Overweight, Diabetes
Interventions
Cell Phone, Weekly access to interactive web site, Group
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
12 Years to 16 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects.

NCT03332927
View directory record Official record
Conditions
PreDiabetes
Interventions
Egg based breakfast foods, Non-egg based breakfast foods
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 30, 2026, 7:49 PM EDT
Not listed Not applicable Interventional

Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting

NCT04564586
View directory record Official record
Conditions
PreDiabetes, Metabolic Syndrome, Protection Against
Interventions
DPPFit
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Sep 30, 2026, 7:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening for Early Evidence of Diabetes

NCT00614783
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Not listed
Lead sponsor
VeraLight, Inc.
Industry
Eligibility
18 Years and older
Enrollment
3,478 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
15
States / cities
Huntsville, Alabama • San Diego, California • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Sleep Intervention (SLEEP-Extend) for Young Adults At-Risk for Type 2 Diabetes

NCT03616171
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
SLEEP-Extend intervention, Control
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 25 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 30, 2019 · Synced Sep 30, 2026, 7:49 PM EDT
Recruiting Phase 1Phase 2 Interventional

Polypill for Prevention of Cardiomyopathy

NCT06143566
View directory record Official record
Conditions
Type 2 Diabetes, High Blood Pressure
Interventions
Polypill, Combined prescription of the individual medications
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Prepare for Your Diabetes Care

NCT05263310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus With Hypoglycemia, Aging, Patient Activation
Interventions
Prepare for Your Diabetes Care, Usual Care
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
75 Years and older
Enrollment
669 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes

NCT04316429
View directory record Official record
Conditions
Type 2 Diabetes, Cardiovascular Diseases
Interventions
Egg included vegan phase, Vegan Phase
Other
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Examination of Bromocriptine on Homeostatic and Hedonic Mechanisms of Food Intake in Individuals at High Risk for T2DM

NCT05405244
View directory record Official record
Conditions
Overweight and Obesity, Eating Behavior
Interventions
Placebo, Bromocriptine-QR
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Sep 30, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Food for Health Study

NCT07254689
View directory record Official record
Conditions
Type 2 Diabetes, Food Insecurity, Rural Health
Interventions
Produce Prescription Program
Behavioral
Lead sponsor
University of Montana
Other
Eligibility
55 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Arlee, Montana
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Phase 2Phase 3 Interventional

Low Glycemic Load Diets in Latino Children at Risk for Type 2 Diabetes

NCT01068197
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
Low Glycemic Load Diet versus Low Fat Diet
Behavioral
Lead sponsor
Nazrat Mirza
Other
Eligibility
7 Years to 14 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Sep 30, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Native Hawaiian Diabetes Intervention Program

NCT00006165
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
'Ohana (Family) Support Lifestyle Intervention
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
30 Years and older
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Mar 2, 2010 · Synced Sep 30, 2026, 7:49 PM EDT