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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:12 PM EDT

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Showing 385–408 of 844 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Attention Deficit and Disruptive Behavior Disorder Clear all
Completed Phase 3 Interventional Results available

Virtual Reality Treatment for Emerging Adults With ADHD

NCT06454604
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Meta Quest 3 VR Headset with noise cancelling headphones
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Baton Rouge, Louisiana • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Completed No phase listed Observational

Autism Spectrum Disorders (ASD) Driving Study

NCT01263756
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 8, 2011 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Statewide Trial to Compare Three Training Models for Implementing an Evidence-based Treatment (EBT)

NCT02543359
View directory record Official record
Conditions
Training of Mental Health Professionals, Disruptive Behavior Disorders
Interventions
Training Models of PCIT, Parent-Child Interaction Therapy (PCIT) Treatment
Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
1 Year and older
Enrollment
648 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 23, 2026, 10:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHD

NCT02897362
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
13 Years to 17 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 2 Interventional

Amphetamine Extended Release Tablets and Driving Performance in Subjects With Attention Deficit/Hyperactivity Disorder (ADHD)

NCT04027361
View directory record Official record
Conditions
ADHD
Interventions
Amphetamine Extended Release (ER) Tablet 20 mg
Drug
Lead sponsor
Tris Pharma, Inc.
Industry
Eligibility
18 Years to 25 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

A Peer-Delivered High School Preparatory Intervention for Students With ADHD

NCT04571320
View directory record Official record
Conditions
ADHD
Interventions
Summer STRIPES, Enhanced School Services as Usual
Behavioral · Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
13 Years to 16 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Recruiting Phase 4 Interventional

Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

NCT05776056
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Methylphenidate, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

Adapting a Web-Based Professional Development for Mexican School Mental Health Providers Delivering Evidence-Based Intervention for ADHD and ODD

NCT05425966
View directory record Official record
Conditions
ADHD, Oppositional Defiant Disorder
Interventions
CLS-R-FUERTE
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder

NCT02402166
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD)
Interventions
SPD489
Drug
Lead sponsor
Shire
Industry
Eligibility
4 Years to 5 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
6
States / cities
Newport Beach, California • Baltimore, Maryland • Las Vegas, Nevada + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Psychological Effects of Tai Chi Training

NCT01681082
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Tai Chi training
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 23 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 23, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NeuroTrainer Cognitive Training For Academic Focus

NCT06512974
View directory record Official record
Conditions
ADHD - Combined Type, ADHD Predominantly Inattentive Type, ADHD, Predominantly Hyperactive - Impulsive
Interventions
NeuroTrainer
Behavioral
Lead sponsor
NeuroTrainer
Industry
Eligibility
11 Years to 17 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
3
States / cities
Marquette, Michigan • Omaha, Nebraska • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional

Evaluating Stress Management Strategies Within the School Readiness Parenting Program

NCT06626750
View directory record Official record
Conditions
Parenting, Stress, Disruptive Behavior Disorder, Parent-Child Relations, ADHD
Interventions
Summer Treatment Program for Pre-Kindergarteners and Kindergarteners, School Readiness Parenting Program (SRPP), Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
4 Years to 6 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD

NCT03103750
View directory record Official record
Conditions
ADHD
Interventions
Magnetic Resonance Imaging (MRI), PHNO, calcitriol, Placebo oral capsule, high-resolution research tomography, Dextro Amphetamine
Procedure · Drug · Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 1 Interventional

A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine in Pediatric Subjects With Attention-deficit/Hyperactivity Disorder

NCT04398225
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Centanafadine
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
4 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Hollywood, Florida
Source: ClinicalTrials.gov public record
Updated Jun 2, 2022 · Synced Oct 23, 2026, 10:12 PM EDT
Not yet recruiting Phase 4 Interventional

EEG Biomarkers for ADHD Stimulant Treatment

NCT07650643
View directory record Official record
Conditions
ADHD
Interventions
methylphenidate HCl, Mixed amphetamine salts extended release
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 11 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 3 Interventional Results available

Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) Patients

NCT01114737
View directory record Official record
Conditions
Phenylketonuria
Interventions
Sapropterin dihydrochloride, Placebo
Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
8 Years to 65 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
26
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 23 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional

STAND Community Trial

NCT02694939
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
STAND (Behavior Therapy + Motivational Interviewing), Usual Care
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
11 Years to 17 Years
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Study of Droxidopa Treatment in Adults With Attention Deficit Hyperactivity Disorder With Co-administration of Carbidopa

NCT00983814
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Droxidopa+Carbidopa
Drug
Lead sponsor
Chelsea Therapeutics
Industry
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 3 Interventional

CLONICEL (Clonidine Sustained Release) as Add-on to Stimulant Medication in 6 to 17 Yr-olds With ADHD

NCT00641329
View directory record Official record
Conditions
ADHD
Interventions
CLONICEL (clonidine HCl sustained release), Placebo
Drug
Lead sponsor
Addrenex Pharmaceuticals, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
23
States / cities
Little Rock, Arkansas • El Centro, California • Irvine, California + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2010 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 3 Interventional

Comparison of Atomoxetine Plus Either Comparator or Placebo in Children With ADHD Who Haven't Responded to Stimulant Therapy

NCT00485550
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Atomoxetine Hydrochloride, Methylphenidate Hydrochloride, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
6 Years to 12 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 13, 2007 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation

NCT00794040
View directory record Official record
Conditions
Mood Disorder, Mental Disorder Diagnosed in Childhood, Attention Deficit and Disruptive Behavior Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Add-on citalopram following optimized methylphenidate, Add-on placebo following optimized methylphenidate
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 17 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

Improving the Outcomes of Adolescents With ADHD Via a Pre-visit Question Prompt List/Video Intervention

NCT05835362
View directory record Official record
Conditions
ADHD
Interventions
Question Prompt List, Video Only
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 17 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Recruiting Phase 1Phase 2 Interventional

Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial

NCT05608434
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Non-adaptive Floreo VR control, Floreo Virtual Reality application
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 16 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 23, 2026, 10:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study of the What the Body Does to the Drug in Subjects With Mild, Moderate, and Severe Liver Dysfunction

NCT02795637
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD), Binge-Eating Disorder Disorder
Interventions
dasotraline
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
5
States / cities
Miami, Florida • Orlando, Florida • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2016 · Synced Oct 23, 2026, 10:12 PM EDT