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ClinicalTrials.gov public records Last synced Oct 27, 2026, 12:51 PM EDT

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Showing 121–144 of 1,088 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional Results available

Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain

NCT05196919
View directory record Official record
Conditions
Facet Joint Pain, Back Pain, Inflammation
Interventions
XT-150, Placebo
Biological
Lead sponsor
Xalud Therapeutics, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Napa, California • Santa Monica, California • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Phase 3 Interventional Results available

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis

NCT01649375
View directory record Official record
Conditions
Anklyosing Spondylitis
Interventions
Secukinumab (75 mg), Placebo, Secukinumab (150 mg)
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
10
States / cities
Mesa, Arizona • Upland, California • Edina, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 27, 2026, 12:51 PM EDT
Not listed Not applicable Interventional

Gamified Rehab vs Take-home Packet Rehab for Non-specific Low Back Pain

NCT05573932
View directory record Official record
Conditions
Non-specific Low Back Pain
Interventions
Leaderboard, Take-home packet
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Not applicable Interventional

Spinal Cord Stimulation in the Treatment of Chronic, Intractable Pain Using the Nalu™ Neurostimulation System

NCT04503109
View directory record Official record
Conditions
Pain, Chronic, Pain, Intractable, Pain, Back
Interventions
Nalu Neurostimulation System
Device
Lead sponsor
Nalu Medical, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
8
States / cities
Larkspur, California • Walnut Creek, California • Washington D.C., District of Columbia + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Early Phase 1 Interventional

Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain

NCT00370799
View directory record Official record
Conditions
Low Back Pain
Interventions
Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone, Caudal Epidural Injection with DepoMedrol
Drug
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 16, 2013 · Synced Oct 27, 2026, 12:51 PM EDT
Recruiting Phase 2 Interventional

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

NCT05986292
View directory record Official record
Conditions
Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
Interventions
LY3016859 ISA, LY3556050 ISA, LY3526318 ISA, LY3857210 ISA, Placebo Oral, Placebo, LY4065967 ISA
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
62
States / cities
Birmingham, Alabama • Glendale, Arizona • Phoenix, Arizona + 52 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 27, 2026, 12:51 PM EDT
Recruiting Phase 3 Interventional

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

NCT05058287
View directory record Official record
Conditions
Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back
Interventions
Depo-Medrol 40Mg/Ml Suspension for Injection, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 27, 2026, 12:51 PM EDT
Completed No phase listed Observational Results available

Examining Racial and SocioEconomic Disparities (ERASED) in Chronic Low Back Pain Study

NCT03338192
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
QST
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 85 Years
Enrollment
281 participants
Timeline
2017 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 27, 2026, 12:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

NCT05504499
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Fusion
Device
Lead sponsor
Pacific Research Institute
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
10
States / cities
Santa Rosa, California • Jupiter, Florida • Slidell, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 27, 2026, 12:51 PM EDT
Recruiting Phase 1 Interventional

Psilocybin in Chronic Low Back Pain and Depression

NCT06355414
View directory record Official record
Conditions
Chronic Low-back Pain, Depression
Interventions
Psilocybin, Methylphenidate
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 27, 2026, 12:51 PM EDT
Active, not recruiting Not applicable Interventional

Improving Access to Chiropractic Care in Community Health Centers

NCT06104605
View directory record Official record
Conditions
Lower Back Pain
Interventions
Institutional interventions, PCPs interventions, Patient interventions
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Meditation-CBT for Opioid-treated Chronic Low Back Pain

NCT01775995
View directory record Official record
Conditions
Chronic Pain, Low Back Pain
Interventions
Meditation-CBT Intervention + Usual Care, Usual Care Alone
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Not applicable Interventional Results available

Telehealth Outreach for Chronic Back Pain

NCT00608530
View directory record Official record
Conditions
Pain, Back Pain
Interventions
Cognitive Behavioral Therapy-Psychologist-Delivered, Supportive Psychotherapy-Psychologist-Delivered, Cognitive Behavioral Therapy Nurse-Delivered, Supportive Psychotherapy-Nurse-Delivered
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Early Physical Therapy Versus Usual Care for Low Back Pain

NCT01556581
View directory record Official record
Conditions
Low Back Pain
Interventions
Usual Care (UC), Early Physical Therapy (PT)
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 27, 2026, 12:51 PM EDT
Recruiting Not applicable Interventional

Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain

NCT05607381
View directory record Official record
Conditions
Low Back Pain, Opioid Use
Interventions
Meditation, Usual care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
La Jolla, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Not applicable Interventional

Role of Steroids and 10% Hypertonic Sodium Chloride in Adhesiolysis in Post Lumbar Surgery Syndrome Patients

NCT01053572
View directory record Official record
Conditions
Low Back Pain
Interventions
Adhesiolysis
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 27, 2026, 12:51 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Brain Mechanisms Supporting Cannabis-induced Pain Relief

NCT04982965
View directory record Official record
Conditions
Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease, Chronic Low-back Pain (cLBP), Chronic Low Back and Leg Pain, Back Pain
Interventions
Active Cannabis, Placebo Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Phase 2 Interventional Results available

Optimization of Spinal Manipulative Therapy Protocols

NCT02868034
View directory record Official record
Conditions
Low Back Pain
Interventions
SMT, Mobilizing Exercises, Activation Exercises, SMT extended
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Not applicable Interventional Results available

Investigating the Clinical Effects of Supporting Neutral Pelvic Position in Sitting

NCT02420093
View directory record Official record
Conditions
Low Back Pain, Strain; Postural
Interventions
"Pelvis Support Assembly"
Device
Lead sponsor
Oakland University
Other
Eligibility
20 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Oct 27, 2026, 12:51 PM EDT
Completed No phase listed Observational

CLassification of Axial SpondyloarthritiS Inception Cohort

NCT03993847
View directory record Official record
Conditions
Spondyloarthritis
Interventions
Not listed
Lead sponsor
Spondyloarthritis Research and Treatment Network
Network
Eligibility
18 Years and older
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
15
States / cities
Long Beach, California • Mather, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Oct 27, 2026, 12:51 PM EDT
Withdrawn Not applicable Interventional

MR Guided High Intensity Focused Ultrasound for Lumbar Back Pain

NCT02291978
View directory record Official record
Conditions
Lumbar Facet Joint Pain
Interventions
ExAblate 2100
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 27, 2026, 12:51 PM EDT
Terminated Not applicable Interventional

Clinical Prediction Rule for Clinical Lumbar Instability

NCT01085448
View directory record Official record
Conditions
Low Back Pain
Interventions
Core Stabilization
Other
Lead sponsor
Drexel University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 27, 2026, 12:51 PM EDT
Completed Not applicable Interventional

Effects of In-Wheel Suspension

NCT04467749
View directory record Official record
Conditions
Spinal Cord Injuries, Fatigue, Back Pain, Neck Pain
Interventions
Suspension Wheel
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 27, 2026, 12:51 PM EDT
Withdrawn Not applicable Interventional

Postural Training Device (UPRIGHT) for Back Pain

NCT03449160
View directory record Official record
Conditions
Back Pain Without Radiation, Back Pain, Low
Interventions
UPRIGHT, physical therapy
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 27, 2026, 12:51 PM EDT