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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Biological Markers of Inflammation Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Effect of L. Reuteri on Biomarkers of Inflammation in Healthy Infants With Colic

NCT01849991
View directory record Official record
Conditions
Gastrointestinal, Colic
Interventions
Lactobacillus reuteri, Placebo
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Weeks to 3 Months
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety Study of Lenalidomide Plus R-CHOP Chemotherapy Versus Placebo Plus R-CHOP Chemotherapy in Untreated ABC Type Diffuse Large B-cell Lymphoma

NCT02285062
View directory record Official record
Conditions
Lymphoma, Large B-Cell, Diffuse
Interventions
lenalidomide, Placebo, Rituximab, Cyclophosphamide, Doxorubicin, prednisone, vincristine
Drug
Lead sponsor
Celgene
Industry
Eligibility
18 Years to 80 Years
Enrollment
570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
22
States / cities
Fayetteville, Arkansas • Orange, California • Sacramento, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Aspirin on Gut Microbiome

NCT02761486
View directory record Official record
Conditions
Healthy
Interventions
Aspirin, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
50 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Jun 11, 2026, 1:01 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Impact of Heavy Alcohol Use on Saliva and Oral Health

NCT06684483
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Not applicable Interventional

An Algorithm Driven Sepsis Prediction Biomarker

NCT03015454
View directory record Official record
Conditions
Sepsis, Septic Shock, Severe Sepsis
Interventions
Severe Sepsis Prediction, Severe Sepsis Detection
Other
Lead sponsor
Dascena
Industry
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Jun 11, 2026, 1:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Acute Cryotherapy on Musculoskeletal Function and Biomarkers

NCT07211412
View directory record Official record
Conditions
Exercise Induced Muscle Damage, Cryotherapy
Interventions
Cryotherapy, Eccentric exercise-induced muscle damage
Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 30 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Completed No phase listed Observational

Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19

NCT04706533
View directory record Official record
Conditions
Covid19, Kidney Diseases, Inflammation, SARS-CoV Infection
Interventions
Biomarkers of inflammation
Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
3,402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Cooling Biomarkers

NCT06542419
View directory record Official record
Conditions
Mental Health, Neurological Health
Interventions
Brain Cooling
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 24 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

CNS Correlates of Extended Sleep Restriction

NCT05547880
View directory record Official record
Conditions
Sleep Restriction
Interventions
[11C]ER176
Drug
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Not listed Phase 4 Interventional

Synergistic Influence of Rivaroxaban on Inflammation and Coagulation Biomarkers in Patients With CAD and PAD on Aspirin Therapy

NCT04059679
View directory record Official record
Conditions
Coronary Artery Disease, Peripheral Artery Disease
Interventions
Rivaroxaban 2.5 Mg Oral Tablet, Aspirin 81 mg
Drug
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Phase 4 Interventional Results available

A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects

NCT02198651
View directory record Official record
Conditions
Rheumatoid Arthritis, Musculoskeletal and Connective Tissue Diseases
Interventions
Adalimumab, Placebo
Biological · Other
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
13
States / cities
Tuscaloosa, Alabama • Thousand Oaks, California • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Jun 11, 2026, 1:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean

NCT04271072
View directory record Official record
Conditions
Perinatal Depression, Chronic Pain
Interventions
No intervention
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease

NCT01038362
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
NCEP Step 1 diet plus Almonds, No Almonds
Other
Lead sponsor
Boston University
Other
Eligibility
21 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 22, 2009 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Acute Effects of E-Cigarette Aerosol Inhalation

NCT03479203
View directory record Official record
Conditions
Endothelial Dysfunction, Biochemical Markers
Interventions
Electronic Cigarette Aerosol
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 35 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Aspirin Attenuates Inflammation in Human Cerebral Aneurysms

NCT01710072
View directory record Official record
Conditions
The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm
Interventions
aspirin
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Jun 11, 2026, 1:01 AM EDT
Terminated Not applicable Interventional

A Study Looking at the Use of Biomarkers to Provide Early Indication of Acute Kidney Injury in Patients With Sepsis (Limiting AKI Progression In Sepsis)

NCT04434209
View directory record Official record
Conditions
Sepsis, Acute Kidney Injury, Septic Shock
Interventions
Subject management guided by NephroCheck® test, Standard of Care
Device · Other
Lead sponsor
BioMérieux
Industry
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Shreveport, Louisiana • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jun 11, 2026, 1:01 AM EDT
Completed No phase listed Observational

Evaluation of Immunoassay Measurements of Pancreatic Stone Protein Performed on abioSCOPE® Device With the PSP Assay on ICU Patients at Risk of Sepsis as an Aid in Identifying Sepsis

NCT04105699
View directory record Official record
Conditions
Sepsis
Interventions
Blood sampling
Device
Lead sponsor
Abionic SA
Industry
Eligibility
18 Years and older
Enrollment
544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Chicago, Illinois • Lexington, Kentucky • Toledo, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Jun 11, 2026, 1:01 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Microbiome of Urologic Chronic Pelvic Pain Syndrome

NCT03027076
View directory record Official record
Conditions
Prostatitis, Chronic Prostatitis, Interstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome
Interventions
Genitourinary Specimen Collection, Collect midstream urine samples
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effects of Immulina TM Supplements With PASC Patients

NCT05524532
View directory record Official record
Conditions
Post Acute COVID-19 Syndrome
Interventions
Immulina TM, Placebo
Drug · Dietary Supplement
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
8
States / cities
Honolulu, Hawaii • Baton Rouge, Louisiana • New Orleans, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers

NCT01692353
View directory record Official record
Conditions
Cardiovascular Disease, Cigarette Smoking
Interventions
Subject's usual brand (UB) tobacco product
Other
Lead sponsor
R.J. Reynolds Tobacco Company
Industry
Eligibility
26 Years to 49 Years · Male only
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 16, 2016 · Synced Jun 11, 2026, 1:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults

NCT06942351
View directory record Official record
Conditions
Aging, Inflammation Biomarkers
Interventions
Walnuts, Crackers
Other
Lead sponsor
Oregon State University
Other
Eligibility
55 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance

NCT06795425
View directory record Official record
Conditions
Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness, Immune Function, Gut Health, Microbiome Analysis, Exercise Performance, Exercise Metabolism
Interventions
Postbiotic Active Lifestyle Blend, Placebo
Dietary Supplement · Other
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Recruiting Not applicable Interventional

Dietary Wild Blueberries and Joint Health

NCT06828159
View directory record Official record
Conditions
Gut -Microbiota, Inflammation Biomarkers, Pain Assessment, Joint Pain
Interventions
Wild blueberry, Placebo
Dietary Supplement
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
40 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Jun 11, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Effects of Almonds on Vascular Reactivity in Patients With Coronary Artery Disease

NCT00782015
View directory record Official record
Conditions
Vascular Disease, Endothelial Dysfunction, Heart Disease, Cardiovascular Diseases, Hypertension
Interventions
Almonds, Placebo Comparator:
Dietary Supplement
Lead sponsor
Tufts University
Other
Eligibility
20 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Jun 11, 2026, 1:01 AM EDT