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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Biopsy, Needle Clear all
Not listed Not applicable Interventional

Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies

NCT04404101
View directory record Official record
Conditions
Pancreatic Cyst
Interventions
1). EUS-FNA plus MFB, 2). EUS-FNA Alone
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Irvine, California • Aurora, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Phase 1 Interventional

A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy

NCT01218854
View directory record Official record
Conditions
Lung Neoplasms, Liver Neoplasms, Kidney Neoplasms, Cancer
Interventions
Needle angle measurement
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Early Phase 1 Interventional

Testing of Different Methods for Determining Whether Breast Cancer Has Spread to the Lymph Nodes

NCT00360152
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Fine needle aspiration biopsy (FNAB), Sentinel Lymph Node Biopsy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 3, 2013 · Synced Jul 23, 2026, 4:26 PM EDT
Completed No phase listed Observational

DNA Microarray Study of Pancreas Cancer

NCT00680420
View directory record Official record
Conditions
Pancreas Cancer
Interventions
fine needle aspiration biopsy
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 6, 2013 · Synced Jul 23, 2026, 4:26 PM EDT
Not listed Not applicable Interventional

Ultrasound-CT Fusion System for Interventional Radiology Procedures

NCT03226535
View directory record Official record
Conditions
CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis, CT Guided Injection of Muscle or Nerve Within the Pelvis
Interventions
Ultrasound-CT Fusion
Device
Lead sponsor
Clear Guide Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

19 Versus 22-Gauge Needle for EUS-LB

NCT02967991
View directory record Official record
Conditions
Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
Interventions
EUS-guided liver biopsy
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Jul 23, 2026, 4:26 PM EDT
Terminated Not applicable Interventional Results available

Comparison of Three Tissue Acquiring Techniques During EUS Guided Biopsies of Solid Tumors.

NCT03264092
View directory record Official record
Conditions
Solid Tumor
Interventions
Endoscopic ultrasound guided fine needle biopsy
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Jul 23, 2026, 4:26 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Liver Biopsy Using a 19 Gauge Fine Needle Biopsy Needle

NCT03910790
View directory record Official record
Conditions
Liver Biopsy
Interventions
19 gauge needle liver biopsy
Device
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Jul 23, 2026, 4:26 PM EDT
Not listed Not applicable Interventional

Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions

NCT01698190
View directory record Official record
Conditions
Pancreatic Tumor, Gastric Tumor, Esophageal Tumor, Lymphadenopathy, Duodenal Tumor
Interventions
Endoscopic ultrasound guided needle tissue acquisition.
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2014 · Synced Jul 23, 2026, 4:26 PM EDT
Recruiting No phase listed Observational

Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

NCT05965180
View directory record Official record
Conditions
Prostate Cancer
Interventions
Fine Needle Photoacoustic Probe
Device
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 23, 2026, 4:26 PM EDT
Terminated Not applicable Interventional Results available

Automated Method for Breast Cancer Detection

NCT03863522
View directory record Official record
Conditions
Breast Cancer Diagnosis
Interventions
Fine needle aspiration, Cancer Detection cartridge
Procedure · Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Baltimore, Maryland • Lutherville-Timonium, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 18, 2021 · Synced Jul 23, 2026, 4:26 PM EDT
Withdrawn Phase 2 Interventional

Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)

NCT02766842
View directory record Official record
Conditions
Mesenchymal Tumor, Autoimmune Pancreatitis, Lymphoma, Solid Tumors
Interventions
EUS-FNB with ProCore needle, EUS-FNB with SharkCore needle, ProCore needle, SharkCore needle
Procedure · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Jul 23, 2026, 4:26 PM EDT
Terminated Not applicable Interventional Results available

EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors

NCT02282111
View directory record Official record
Conditions
Esophageal Subepithelial Lesions
Interventions
22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional Results available

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle

NCT01769248
View directory record Official record
Conditions
Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
Interventions
Fine needle aspiration, Fine needle biopsy
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Los Angeles, California • San Francisco, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Jul 23, 2026, 4:26 PM EDT
Active, not recruiting No phase listed Observational

Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform (ELEPHAS-01)

NCT05478538
View directory record Official record
Conditions
NSCLC (Non-small Cell Lung Cancer), Metastatic NSCLC - Non-Small Cell Lung Cancer
Interventions
Core Needle, Forceps, or Punch Biopsy
Procedure
Lead sponsor
Elephas
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Los Angeles, California • Frederick, Maryland • Shirley, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional

Comparison of Two Types of Biopsy in Patients With Breast Lesions

NCT00006031
View directory record Official record
Conditions
Breast Cancer
Interventions
Needle localized breast biopsy with specimen x-ray, Low dose radioactive seed followed by surgery and mammogram
Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2006
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2012 · Synced Jul 23, 2026, 4:26 PM EDT
Terminated Not applicable Interventional Results available

EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses

NCT03485924
View directory record Official record
Conditions
Fine Needle Aspiration, Pancreatic Mass
Interventions
EUS-FNA with ROSE, EUS-FNB without ROSE
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional

Endoscopic Ultrasound Guided Liver Biopsy

NCT03307811
View directory record Official record
Conditions
Hepatic Cancer, Hepatic Neoplasm, Hepatic Carcinoma
Interventions
22 gauge needle liver biopsy
Other
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional

Comparing Methods to Biopsy Pancreas Mass

NCT01663493
View directory record Official record
Conditions
Pancreas Mass Diagnosis
Interventions
FNB
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional

Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy

NCT03290677
View directory record Official record
Conditions
Lung Cancer
Interventions
Cryoablation, Biopsy
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Jul 23, 2026, 4:26 PM EDT
Not yet recruiting Not applicable Interventional

Comparison of FNB to EUS-CNB for Pancreatic Lesions

NCT07240818
View directory record Official record
Conditions
Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
Interventions
endoscopic ultrasound guided biopsy with core needle biopsy device, EUS-FNB
Device · Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 23, 2026, 4:26 PM EDT
Not listed Not applicable Interventional

Randomized Trial for Optimal Number of Passes Required for Molecular Profiling During EUS-FNB of Pancreatic Cancer

NCT05043532
View directory record Official record
Conditions
Pancreatic Cancer, Pancreatic Neoplasms, Adenocarcinoma of the Pancreas
Interventions
2 passes during EUS-guided fine needle biopsy, 3 passes during EUS-guided fine needle biopsy
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Jul 23, 2026, 4:26 PM EDT
Recruiting No phase listed Observational

Studies on Tumors of the Thyroid

NCT00001160
View directory record Official record
Conditions
Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer, Follicular Thyroid Cancer, Thyroid Cancer, Papillary Thyroid Cancer
Interventions
68-Gallium Dotatate
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
6 Months to 98 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1977
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 23, 2026, 4:26 PM EDT
Completed Not applicable Interventional

Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses

NCT02911974
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 23, 2026, 4:26 PM EDT