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Showing 1–24 of 1,066 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Trial of Weaning of Nasal Continuous Positive Airway Pressure (CPAP)

NCT01215591
View directory record Official record
Conditions
Preterm Neonates
Interventions
Gradual weaning from Nasal CPAP in preterm neonates
Procedure
Lead sponsor
Maimonides Medical Center
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2012 · Synced Sep 13, 2026, 7:40 AM EDT
Active, not recruiting No phase listed Observational

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

NCT03782610
View directory record Official record
Conditions
Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia, Neurodevelopmental Abnormality
Interventions
Not listed
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 72 Hours
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
4
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 13, 2026, 7:40 AM EDT
Completed No phase listed Observational

Prediction of Extubation Readiness in Extreme Preterm Infants by the Automated Analysis of CardioRespiratory Behavior

NCT01909947
View directory record Official record
Conditions
Prediction of Extubation Readiness
Interventions
Cardiorespiratory signal acquisition
Other
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
Not listed
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Detroit, Michigan • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 31, 2019 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Phase 2 Interventional

Early Protein Supplementation of Human Milk in Extremely Low Birth Weight Infants

NCT01991613
View directory record Official record
Conditions
Growth in Premature Infants
Interventions
liquid protein supplement
Dietary Supplement
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
26 Weeks to 33 Weeks
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2015 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Phase 3 Interventional Results available

Prospective Randomized Clinical Trial of Intravenous Lipids and Cholestasis

NCT01555957
View directory record Official record
Conditions
Parenteral Nutrition Associated Cholestasis
Interventions
intravenous lipid
Drug
Lead sponsor
University of Rochester
Other
Eligibility
Up to 72 Hours
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring the Feasibility of Centering Pregnancy With Care Navigation

NCT05645549
View directory record Official record
Conditions
Premature Birth
Interventions
Centering Pregnancy with Care Navigation
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 13, 2026, 7:40 AM EDT
Active, not recruiting Not applicable Interventional

Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants

NCT05525585
View directory record Official record
Conditions
Prematurity, Light-For-Dates, Enteral Feeding Intolerance
Interventions
Early HMF, Delayed HMF
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 4 Days
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Novel Parent Education Program for Early Intervention

NCT04266717
View directory record Official record
Conditions
Preterm Infant, Full-term Infant
Interventions
Baby Play Intervention, Milestone Education
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
1 Month to 1 Year
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 13, 2026, 7:40 AM EDT
Not yet recruiting Phase 2 Interventional

Single-dose Prophylactic INdomethacin in Extremely Preterm Infants

NCT06572917
View directory record Official record
Conditions
Extreme Prematurity, Intraventricular Hemorrhage, Morbidity;Newborn
Interventions
Indomethacin, Placebo
Drug
Lead sponsor
University of British Columbia
Other
Eligibility
0 Hours to 12 Hours
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
5
States / cities
Roseville, California • Sacramento, California • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.

NCT01050647
View directory record Official record
Conditions
Pregnancy Complications
Interventions
17-Hydroxyprogesterone Caproate, Caster Oil injections
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Sep 13, 2026, 7:40 AM EDT
Completed No phase listed Observational

Neurophysiologic Maturation Index for Late Preterm Infants

NCT02156817
View directory record Official record
Conditions
Neurophysiologic Maturation
Interventions
Amplitude integrated electroencephalogram, Cardiorespiratory signal acquisition
Other
Lead sponsor
Brown University
Other
Eligibility
1 Day to 4 Days
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Detroit, Michigan • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 13, 2026, 7:40 AM EDT
Completed No phase listed Observational

Evaluating Patterned Oral Somatosensory Entrainment Stimulation Using the NTrainer on Oral Feeding Performance

NCT01069718
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
KC BioMediX, Inc
Industry
Eligibility
34 Weeks to 18 Months
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2010 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional

Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA

NCT03242057
View directory record Official record
Conditions
Preterm Infant, BPD - Bronchopulmonary Dysplasia, Barotrauma
Interventions
NAVA, NIPPV
Other
Lead sponsor
University of Florida
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 13, 2026, 7:40 AM EDT
Terminated Phase 1 Interventional Results available

A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for BPD

NCT03857841
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
UNEX-42, Phosphate-buffered saline
Biological
Lead sponsor
United Therapeutics
Industry
Eligibility
3 Days to 14 Days
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
6
States / cities
Aurora, Colorado • Boston, Massachusetts • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Dosing of Levetiracetam (Keppra) in Neonates

NCT01239212
View directory record Official record
Conditions
Seizures
Interventions
levetiracetam
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day to 30 Days
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Euglycemia After Antenatal Late Preterm Steroids, the E-ALPS Study

NCT03076775
View directory record Official record
Conditions
Pregnancy Preterm, Neonatal Hypoglycemia, Hyperglycemia Drug Induced
Interventions
Maternal glycemic control
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Birmingham, Alabama • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Sep 13, 2026, 7:40 AM EDT
Not listed Not applicable Interventional

Cycled Phototherapy: A Safer Effective Treatment for Small Premature Infants?

NCT01944696
View directory record Official record
Conditions
Hyperbilirubinemia, Premature Newborns, Extremely Low Birth Weight
Interventions
phototherapy
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 24 Hours
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
6
States / cities
Birmingham, Alabama • Palo Alto, California • Cincinnati, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2016 · Synced Sep 13, 2026, 7:40 AM EDT
Completed No phase listed Observational

Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease

NCT01126372
View directory record Official record
Conditions
Congenital Heart Disease, Prematurity, Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 1 Month
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Trial of Social Network Targeting in Honduras

NCT02694679
View directory record Official record
Conditions
Preterm Delivery, Hypothermia, Diarrhea, Upper Respiratory Infection, Omphalitis
Interventions
CBNH
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years and older
Enrollment
31,195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional Results available

Incubator Weaning of Moderately Preterm Infants

NCT02160002
View directory record Official record
Conditions
Infant, Newborn, Infant, Moderate Preterm
Interventions
Weaning from an incubator at a lower weight (1600 grams), Weaning from an incubator at a higher weight (1800 grams)
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
29 Weeks to 34 Weeks
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
18
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Phase 3 Interventional

Nutritional Study in Preterm Infants

NCT00707837
View directory record Official record
Conditions
Preterm Infants
Interventions
Preterm infant formulas and discharge formulas, Preterm infant formula with added soluble lipids
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
Up to 21 Days
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
Birmingham, Alabama • St. Petersburg, Florida • Tampa, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2009 · Synced Sep 13, 2026, 7:40 AM EDT
Completed Not applicable Interventional Results available

Optimizing Individual Nutrition in Preterm Very Low Birth Weight Infants

NCT02372136
View directory record Official record
Conditions
Infant, Premature, Diseases, Infant, Small for Gestational Age
Interventions
Individualized Nutrition, Optimized nutrition
Dietary Supplement
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 7 Days
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 13, 2026, 7:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Minor Increase Over Minimal Risk Research in NICU

NCT02482012
View directory record Official record
Conditions
Infant, Premature, Infant, Late, Infant, Preterm, Infant
Interventions
Survey
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Sep 13, 2026, 7:40 AM EDT
Completed No phase listed Observational

Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus

NCT03551600
View directory record Official record
Conditions
Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
Interventions
Near-infrared spectroscopy (NIRS)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
12 Days to 6 Months
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Sep 13, 2026, 7:40 AM EDT