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ClinicalTrials.gov public records Last synced Oct 13, 2026, 1:24 AM EDT

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Showing 289–312 of 3,926 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Blood Pressure, High Clear all
Active, not recruiting Phase 1Phase 2 Interventional

A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors

NCT06777316
View directory record Official record
Conditions
Intrahepatic Cholangiocarcinoma (Icc), Cholangiocarcinoma, Other Solid Tumors, Adult, FGFR2 Gene Fusion/Rearrangement, FGFR2 Gene Amplification, FGFR2 Gene Short Variants, FGFR3 Gene Fusion/Rearrangement, FGFR3 Gene Amplification, FGFR3 Gene Short Variants, FGFR2 Genetic Alterations, FGFR3 Genetic Alterations, Advanced Solid Tumors
Interventions
CGT4859
Drug
Lead sponsor
Cogent Biosciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
12
States / cities
Palo Alto, California • Jacksonville, Florida • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional

Enhanced Spanish Drug Label Study to Promote Patient Understanding and Use

NCT01200849
View directory record Official record
Conditions
Medication Understanding, Diabetes, Hypertension
Interventions
Enhanced Label
Other
Lead sponsor
Northwestern University
Other
Eligibility
30 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2014 · Synced Oct 13, 2026, 1:24 AM EDT
Completed No phase listed Observational

TIPS Plus Transvenous Obliteration for Gastric Varices

NCT04044248
View directory record Official record
Conditions
Cirrhosis, Liver, Hypertension, Portal, Esophageal and Gastric Varices, Bleeding Gastric, Encephalopathy
Interventions
TIPS-obliteration
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
8 participants
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia

NCT02147626
View directory record Official record
Conditions
Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
Interventions
Web-based educational and motivational modules, Information and Screening Group
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional

Feasibility And Safety Of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation Using A Radiofrequency Guidewire

NCT03451149
View directory record Official record
Conditions
Portal Hypertension
Interventions
Radiofrequency wire (Powerwire)
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 3, 2023 · Synced Oct 13, 2026, 1:24 AM EDT
Recruiting Not applicable Interventional

Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury

NCT07504055
View directory record Official record
Conditions
Spinal Cord Injury, Orthostatic Hypertension, Autonomic Dysreflexia
Interventions
Spinal Cord Transcutaneous Stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.

NCT01033071
View directory record Official record
Conditions
Essential Hypertension
Interventions
Azilsartan medoxomil and chlorthalidone, Olmesartan medoxomil and hydrochlorothiazide
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
1,071 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
84
States / cities
Gulf Shores, Alabama • Litchfield Park, Arizona • Mesa, Arizona + 81 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2012 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional

A ED-based Intervention to Improve Antihypertensive Adherence

NCT02672787
View directory record Official record
Conditions
Hypertensive Emergency, Hypertension, Blood Pressure
Interventions
ED-based behavioral intervention, ED usual care plus education
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 85 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional Results available

Hypertension In Postpartum Preeclampsia Study

NCT03011567
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced
Interventions
Acetaminophen, Ibuprofen
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2024 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional

Improving Quality With Outpatient Decision Support

NCT00225628
View directory record Official record
Conditions
Diabetes Mellitus, Coronary Artery Disease, Osteoporosis, Hypertension, Hyperlipidemia
Interventions
Computerized Reminders Medications Monitoring, Computerized Test Results Management Application, Computerized Reminders Hypertension Management, Computerized Reminders Osteoporosis Screening and Mgt
Behavioral
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Federal
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2005 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional

Evaluation of a Navigator-Nurse Care Team on the Management of High Blood Pressure and Cardiovascular Disease Risk

NCT00523536
View directory record Official record
Conditions
Hypertension
Interventions
Patient Navigator - Nurse Team Intervention
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
21 Years to 74 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 2, 2013 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Phase 2 Interventional Results available

POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma

NCT02466399
View directory record Official record
Conditions
Glaucoma
Interventions
POLAT-001, Latanoprost ophthalmic solution
Drug
Lead sponsor
Peregrine Ophthalmic
Industry
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Goose Creek, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 13, 2026, 1:24 AM EDT
Terminated Not applicable Interventional Results available

ActiV.A.C.+ Compression Therapy Versus Compression Therapy Alone for the Treatment of Chronic Venous Ulcerations

NCT01528293
View directory record Official record
Conditions
Chronic Venous Hypertension With Ulcer
Interventions
ActiVAC System, Compression therapy
Device · Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Phase 2 Interventional Results available

A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular Hypertension

NCT00538304
View directory record Official record
Conditions
Glaucoma, Ocular Hypertension
Interventions
bimatoprost eye drops, placebo
Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vascular Effects of Acute Sodium (VEAS) Study

NCT04244604
View directory record Official record
Conditions
Sodium Excess, Racial Disparities, Blood Pressure, Cardiovascular Risk Factor
Interventions
Low Sodium Meal (140 mg sodium chloride), High Sodium Meal (2500 mg sodium chloride)
Other
Lead sponsor
Indiana University
Other
Eligibility
19 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Auburn, Alabama • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 13, 2026, 1:24 AM EDT
Terminated Phase 4 Interventional Results available

Postpartum Hypertension Study

NCT05139238
View directory record Official record
Conditions
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
Interventions
Labetalol, Nifedipine
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Phase 2 Interventional Results available

Biomarker Guided Therapies in Stage A/B Heart Failure

NCT02230891
View directory record Official record
Conditions
Hypertension, Diabetes, Cardiovascular Disease
Interventions
Carvedilol, Spironolactone, Usual care
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2022 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Phase 4 Interventional

Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension

NCT00300079
View directory record Official record
Conditions
Primary Open Angle Glaucoma, Ocular Hypertension
Interventions
brinzolamide 1.0%
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2016 · Synced Oct 13, 2026, 1:24 AM EDT
Recruiting Not applicable Interventional

Mobile Health Program for Post-Preeclampsia Hypertension

NCT07599579
View directory record Official record
Conditions
Hypertension (HTN), Preeclampsia, Hypertensive Disorders of Pregnancy (HDP)
Interventions
Coaching application, Home-based blood pressure monitoring, WebMD
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 13, 2026, 1:24 AM EDT
Not yet recruiting Not applicable Interventional

Beta-2 Adrenergic Receptor Polymorphic Variants: An Endotype of Salt Sensitive Hypertension (Beta2AR).

NCT07832942
View directory record Official record
Conditions
Genetics in Hypertension
Interventions
low sodium diet, high sodium diet, renal plasma flow, SIEA collection
Other · Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 13, 2026, 1:24 AM EDT
Terminated Phase 4 Interventional Results available

Is Procardia XL 60 mg Q Daily Equivalent to 30 mg XL Given Twice Daily?

NCT03595982
View directory record Official record
Conditions
Hypertension in Pregnancy, Hypertension in Postpartum
Interventions
Procardia XL 30Mg, Procardia XL 60Mg
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 13, 2026, 1:24 AM EDT
Completed Phase 3 Interventional

Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70

NCT00047541
View directory record Official record
Conditions
Open-Angle Glaucoma, Ocular Hypertension
Interventions
Alcon Investigational Agent
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2008 · Synced Oct 13, 2026, 1:24 AM EDT
Recruiting Not applicable Interventional

Penn Medicine Healthy Heart

NCT06062394
View directory record Official record
Conditions
Hypertension, Hyperlipidemias
Interventions
Penn Med Healthy Heart Program
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
35 Years to 80 Years
Enrollment
1,980 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 13, 2026, 1:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Perimetric Testing With Virtual Reality

NCT06549010
View directory record Official record
Conditions
Glaucoma
Interventions
Perimetric test
Diagnostic Test
Lead sponsor
Envision Health Technologies, Inc.
Industry
Eligibility
25 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Oct 13, 2026, 1:24 AM EDT