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ClinicalTrials.gov public records Last synced Oct 12, 2026, 12:22 AM EDT

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Showing 121–144 of 3,926 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Blood Pressure, High Clear all
Not listed Phase 3 Interventional

Advanced Glaucoma Intervention Study (AGIS)

NCT00000148
View directory record Official record
Conditions
Glaucoma
Interventions
Argon Laser Trabeculoplasty, Trabeculectomy
Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
35 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1988
U.S. locations
13
States / cities
New Haven, Connecticut • Washington D.C., District of Columbia • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2006 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

NCT03931317
View directory record Official record
Conditions
OAG - Open-Angle Glaucoma, OHT - Ocular Hypertension
Interventions
Latanoprostene bunod 0.024% QD, Timolol maleate 0.5% BID
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Oct 12, 2026, 12:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Boosting Primary Care Awareness and Treatment of Childhood Hypertension

NCT03783650
View directory record Official record
Conditions
Pediatric Hypertension
Interventions
Control condition, QIC with PCP and without subspecialist, QIC with Subspecialist, Hub and Spoke co-management, Sustainability of changes
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 12, 2026, 12:22 AM EDT
Withdrawn Not applicable Interventional

Docosahexaenoic Acid Supplementation of Women With Hypertension in Pregnancy to Improve Endothelial Health

NCT02137408
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Docosahexaenoic acid 200 mg, Docosahexaenoic acid 1000 mg
Dietary Supplement · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2014 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Phase 4 Interventional

Effect of Celecoxib on Markers of Vascular Inflammation

NCT00471341
View directory record Official record
Conditions
Hypertension and Coronary Artery Disease
Interventions
Celecoxib, placebo
Drug
Lead sponsor
University of Florida
Other
Eligibility
50 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
2
States / cities
Gainesville, Florida • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2011 · Synced Oct 12, 2026, 12:22 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Tailored Messages to Increase Eye Examination Behavior

NCT00649766
View directory record Official record
Conditions
Eye Disease, Eye Care
Interventions
tailored newsletter, targeted newsletter
Behavioral
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
65 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional Results available

A Study of Cardiovascular Disparities in the Greater Mankato Somali Community to Prevent Hypertension

NCT05873153
View directory record Official record
Conditions
Hypertension
Interventions
Health Education, Home Blood Pressure Monitor
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Mankato, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional

A Pilot Study to Determine the Efficacy of a Low Carbohydrate Diet in Treatment of Adolescents With Metabolic Syndrome

NCT00940966
View directory record Official record
Conditions
Elevated Triglycerides, Systolic Hypertension, Insulin Resistance, Abdominal Obesity
Interventions
standard ADA diet, energy restricted very-low carbohydrate diet, low glycemic diet
Dietary Supplement
Lead sponsor
CAMC Health System
Other
Eligibility
12 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Stretching Training on Arterial Function and Autonomic Control

NCT01741766
View directory record Official record
Conditions
Obesity, Pre-hypertension, Hypertension
Interventions
Stretching Training
Other
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 5, 2012 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Phase 3 Interventional Results available

The CLEVER Study - Coreg And Left Ventricular Mass Regression

NCT00108082
View directory record Official record
Conditions
Hypertrophy, Left Ventricular
Interventions
carvedilol MR, atenolol, lisinopril
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
78
States / cities
Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 65 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2016 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional Results available

SMS System for Patients With Uncontrolled Hypertension

NCT03596242
View directory record Official record
Conditions
Hypertension
Interventions
SMS System, blood pressure control education
Other · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 12, 2026, 12:22 AM EDT
Withdrawn Not applicable Interventional

Utilizing Telemedicine for Hypertension Treatment Lifestyle Modification in Central Harlem

NCT05062473
View directory record Official record
Conditions
Hypertension
Interventions
Lifestyle Modification Webinars Focused on Hypertension Control
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 12, 2026, 12:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Intergenerational Blood Pressure Study

NCT03013179
View directory record Official record
Conditions
Hypertension
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
3 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Orange, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 20, 2020 · Synced Oct 12, 2026, 12:22 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Screening Protocol

NCT06135727
View directory record Official record
Conditions
Glaucoma
Interventions
Maestro2 OCT
Device
Lead sponsor
Topcon Corporation
Industry
Eligibility
22 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension

NCT00818883
View directory record Official record
Conditions
Essential Hypertension
Interventions
Azilsartan medoxomil and chlorthalidone, Azilsartan medoxomil and hydrochlorothiazide
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
50
States / cities
Birmingham, Alabama • Gulf Shores, Alabama • Scottsboro, Alabama + 47 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2012 · Synced Oct 12, 2026, 12:22 AM EDT
Completed No phase listed Observational

Pulmonary Hypertension in Trisomy 21 Patients

NCT00478296
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 8 Days
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional

A Pilot Study of a Lifestyle Intervention on the Metabolic Syndrome (3ELM Study)

NCT02233088
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
ELM Group, ELM Classes, ELM Individual
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 72 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Oct 12, 2026, 12:22 AM EDT
Completed No phase listed Observational

Comparison of Gonioscopy With Cirrus and Visante

NCT01895686
View directory record Official record
Conditions
Open Angle Glaucoma, Narrow Angles, Angle Closure Glaucoma
Interventions
Not listed
Lead sponsor
Wills Eye
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional

Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects

NCT04285554
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
iRF System Hepatic Denervation
Device
Lead sponsor
Metavention
Industry
Eligibility
22 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
8
States / cities
Birmingham, Alabama • Stanford, California • Orlando, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Dietary Antioxidants on Cardiovascular Risk Factors

NCT00756405
View directory record Official record
Conditions
Obesity, Hyperlipidemia, Hypertension
Interventions
Antioxidant diet, Antioxidant supplement, Placebo
Behavioral · Dietary Supplement
Lead sponsor
Christopher Gardner
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 12, 2026, 12:22 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Post-exercise Blood Pressure With Inorganic Nitrate

NCT07869472
View directory record Official record
Conditions
Obese Individuals, Central Adiposity
Interventions
Beetroot Juice - Active + Exercise, Beetroot juice placebo + Exercise, Beetroot Juice - Active + No exercise, Beetroot juice placebo+ No exercise
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 12, 2026, 12:22 AM EDT
Active, not recruiting Not applicable Interventional

Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension

NCT07130539
View directory record Official record
Conditions
Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
Interventions
MIND HIIT
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 74 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 12, 2026, 12:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Tolerance to Target Doses of Thiazides in Actual Practice: A Feasibility Study

NCT01235377
View directory record Official record
Conditions
Hypertension
Interventions
Favor one of two thiazides for new prescriptions & attempt target dose
Other
Lead sponsor
VA Pharmacy Benefits Management Strategic Healthcare Group
Federal
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
5
States / cities
Hines, Illinois • Asheville, North Carolina • Wilkes-Barre, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2014 · Synced Oct 12, 2026, 12:22 AM EDT
Active, not recruiting Phase 2 Interventional

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

NCT07354477
View directory record Official record
Conditions
Non-proliferative Diabetic Retinopathy (NPDR), Open-angle Glaucoma (OAG), Normal Tension Glaucoma (NTG)
Interventions
QLS-111 Ophthalmic Solution (0.015%), QLS-111 Ophthalmic Solution (0.075%)
Drug
Lead sponsor
Qlaris Bio, Inc.
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 12, 2026, 12:22 AM EDT