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ClinicalTrials.gov public records Last synced Oct 25, 2026, 4:07 AM EDT

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Showing 49–72 of 287 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Body Temperature Changes Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Aging and Gastrointestinal Barrier Function

NCT05816551
View directory record Official record
Conditions
Aging, Hyperthermia
Interventions
Hyperthermia Trial, Control Trial
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 25, 2026, 4:07 AM EDT
Not listed No phase listed Observational

Describing Chinese Herbal Medicine Telehealth Care for Symptoms Related to Infectious Diseases Such as COVID-19

NCT04380870
View directory record Official record
Conditions
Coronavirus Infection
Interventions
Chinese Herbal Medicine
Dietary Supplement
Lead sponsor
Center for Integrated Care
Other
Eligibility
18 Years to 114 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 25, 2026, 4:07 AM EDT
Recruiting Not applicable Interventional

Prescription Antipyretics to Decrease Unscheduled Return Visits In A Pediatric Emergency Department

NCT07074912
View directory record Official record
Conditions
Fever
Interventions
Prescription for weight-based dosing of antipyretic, Standard discharge instructions
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
6 Months to 36 Months
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 25, 2026, 4:07 AM EDT
Terminated Phase 3 Interventional Results available

Effects of Hypothermia Upon Outcomes After Acute Traumatic Brain Injury

NCT00178711
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Hypothermia
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
16 Years to 45 Years
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
4
States / cities
St Louis, Missouri • Pittsburgh, Pennsylvania • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Oct 25, 2026, 4:07 AM EDT
Recruiting Not applicable Interventional

Heat thErapy And mobiLity in COVID-19 Survivors

NCT06928116
View directory record Official record
Conditions
Long COVID
Interventions
Heat therapy, Sham Control, Walking
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 90 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 25, 2026, 4:07 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Hypothermia in Acute Stroke With Thrombolysis Imaging Evaluation of Revascularization

NCT01778855
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
IV t-PA and normothermia, IV-tPA and hypothermia
Other · Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
22 Years to 82 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Los Angeles, California • San Diego, California • Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional

Lidocaine Lubricant in Pediatric Urethral Catheterization

NCT00596375
View directory record Official record
Conditions
Fevers, Pain
Interventions
Lubricant Instillation, Lidocaine Lubricant
Procedure · Drug
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
2 Months to 2 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 17, 2008 · Synced Oct 25, 2026, 4:07 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Malignant Hyperthermia Registry and Genetic Testing

NCT02964481
View directory record Official record
Conditions
Malignant Hyperthermia
Interventions
Whole exome sequencing
Genetic
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 25, 2026, 4:07 AM EDT
Completed No phase listed Observational

Circulating-water Garment With Forced-air Warming and Circulating-water Mattress During Abdominal Surgery

NCT00651898
View directory record Official record
Conditions
Hypothermia
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2016 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Phase 3 Interventional

Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316

NCT02026349
View directory record Official record
Conditions
Influenza
Interventions
favipiravir, Placebo
Drug
Lead sponsor
MDVI, LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
60
States / cities
Birmingham, Alabama • Hunstville, Alabama • Hot Springs, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Renal Considerations in the Heat Stress Recommendations (Aim2)

NCT05458843
View directory record Official record
Conditions
Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia, Dehydration
Interventions
Fluid replacement, No fluid replacement
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Oct 25, 2026, 4:07 AM EDT
Recruiting No phase listed Observational

Diagnosis and Management of Inflammatory and Infectious Diseases

NCT00557726
View directory record Official record
Conditions
Infection, Inflammation
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
3 Years to 100 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1978
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 25, 2026, 4:07 AM EDT
Terminated Not applicable Interventional Results available

Impact of Fever Prevention in Brain Injured Patients

NCT02996266
View directory record Official record
Conditions
Fever, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
Interventions
Targeted Temperature Management, Standard Care
Device · Other
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years to 85 Years
Enrollment
686 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
28
States / cities
Los Angeles, California • Palo Alto, California • Aurora, Colorado + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment

NCT04715711
View directory record Official record
Conditions
Hyperthermia
Interventions
Forearm coolng, Wet-towel cooling, mist-fan, passive cooling
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 28 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

NCT06042270
View directory record Official record
Conditions
Body Temperature Changes, Body Water Dehydration, Inflammation
Interventions
Betaine, Placebo
Dietary Supplement
Lead sponsor
Michael J. Ormsbee
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Heat Exposure on Cognition in Persons With Tetraplegia

NCT02488824
View directory record Official record
Conditions
Tetraplegia, Hypothermia, Mild Cognitive Impairment
Interventions
Warm Temperature
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 68 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Phase 3 Interventional

Discrete Hypothermia in the Management of Traumatic Brain Injury

NCT00676104
View directory record Official record
Conditions
Severe Traumatic Brain Injury
Interventions
CoolSystems Discrete Cerebral Hypothermia System
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 20, 2013 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Validity of CORE Sensor in Heat Training for Male and Female Endurance Athletes

NCT05692947
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Core body temperature device
Device
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 25, 2026, 4:07 AM EDT
Completed No phase listed Observational Results available

Evaluation of Moderate to Severe Influenza Outcomes in Children

NCT02979626
View directory record Official record
Conditions
Influenza, Otitis Media, Lower Resp Tract Infection, Encephalitic Infection, Myositis Viral, Fever
Interventions
Respiratory nasal swab
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Months to 8 Years
Enrollment
1,478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Aurora, Colorado • Broomfield, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Work-To-Rest Ratios

NCT05327764
View directory record Official record
Conditions
Hyperthermia
Interventions
Work to rest cycles of 40:20 minutes, Work to rest cycles of 20:10 minutes
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2023 · Synced Oct 25, 2026, 4:07 AM EDT
Withdrawn Phase 2 Interventional

REperfusion With Cooling in CerebraL Acute IscheMia II

NCT02411877
View directory record Official record
Conditions
Ischemic Stroke, Hypothermia
Interventions
Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.), Zoll Thermogard XP technology with the Quattro catheter
Procedure · Device
Lead sponsor
WellStar Health System
Other
Eligibility
18 Years to 79 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Oct 25, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Prophylactic Antipyretics on Immune Responses and Fever After 2014-2015 and 2015-2016 Inactivated Influenza Vaccine

NCT02212990
View directory record Official record
Conditions
Fever
Interventions
Acetaminophen Arm, Placebo Arm, Ibuprofen Arm
Other
Lead sponsor
Duke University
Other
Eligibility
6 Months to 47 Months
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 25, 2026, 4:07 AM EDT
Terminated Not applicable Interventional Results available

To Study the Effect of Early Cooling in Acute Subdural Hematoma Patients

NCT02064959
View directory record Official record
Conditions
Subdural Hematoma, Traumatic
Interventions
Temperature management Zoll Intravascular Temperature Management device
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
22 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
5
States / cities
Miami, Florida • Atlanta, Georgia • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 25, 2026, 4:07 AM EDT
Recruiting Not applicable Interventional

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

NCT02991690
View directory record Official record
Conditions
Spinal Cord Injury, Acute
Interventions
Alsius Icy CoolGuard® Catheter
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
7
States / cities
Phoenix, Arizona • Miami, Florida • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 25, 2026, 4:07 AM EDT