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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:37 PM EDT

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Showing 385–408 of 6,936 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Body Weight Clear all
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

A Study of Brenipatide (LY3537031) in Healthy Participants With Overweight or Obesity

NCT07476118
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Brenipatide, Placebo
Drug · Other
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Daytona Beach, Florida • Dallas, Texas • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional

Nutrition and Exercise Trial: Improving Diet and Physical Activity Patterns in Overweight Cancer Survivors

NCT03489213
View directory record Official record
Conditions
Cancer Survivor, Overweight
Interventions
Dietary Intervention, Exercise Intervention, Laboratory Biomarker Analysis, Nutritional Intervention, Questionnaire Administration
Other · Behavioral · Dietary Supplement
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional

Intervention Study of Cost-Offset Community Supported Agriculture (CO-CSA)

NCT02770196
View directory record Official record
Conditions
Pediatric Obesity, Child Nutrition Disorders
Interventions
CO-CSA plus Nutrition Education
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
29
States / cities
Barker, New York • Corning, New York • Gasport, New York + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Not listed Early Phase 1 Interventional

Effect of Intense Multi-modal Training on Bone Health and Quality of Life in Persons With Spinal Cord Injury

NCT01386762
View directory record Official record
Conditions
Spinal Cord Injury, Obesity
Interventions
Exercise training
Other
Lead sponsor
California State University, San Marcos
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2011 · Synced Oct 21, 2026, 2:37 PM EDT
Recruiting Not applicable Interventional

Effects of Ultra Processed Food on Intestinal Energy Harvest

NCT06853288
View directory record Official record
Conditions
Obesity and Overweight
Interventions
Diet containing 80% ultra processed foods, Diet containing 20% ultra processed foods
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
25 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Obesity

NCT01580761
View directory record Official record
Conditions
Obesity
Interventions
Sleep restriction
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 40 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 21, 2022 · Synced Oct 21, 2026, 2:37 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

NCT02282423
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Pre-study dietary and exercise instruction., Screening examination and oral glucose tolerance test, Euglycemic clamp, VO2max., Acute exercise bout, Percutaneous needle muscle biopsies
Behavioral · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 59 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Phase 3 Interventional

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

NCT05929079
View directory record Official record
Conditions
Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
Interventions
Retatrutide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
1,152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
40
States / cities
Anniston, Alabama • Cullman, Alabama • Little Rock, Arkansas + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Collection of Human Tissue Samples From the Neck Region for Characterization of Its Molecular and Biochemical Signatures

NCT02274805
View directory record Official record
Conditions
Obesity
Interventions
Adults presenting for surgery in the neck area
Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Sugar Reduction Intervention in Kiritimati Teenagers

NCT04319003
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Sugar-reduction intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
10 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional Results available

Family-Based Treatment for Type 1 Diabetes

NCT05756361
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Obesity, Childhood, Overweight, Comorbidities and Coexisting Conditions
Interventions
Family-Based Treatment for T1D
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
6 Years to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional

Iron Absorption in The Low Oxygen Exposure and Weight Status (LOWS) Study

NCT07542873
View directory record Official record
Conditions
Obesity (Disorder)
Interventions
Normobaric hypoxia (NH), Normobaric normoxia (NN)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
22 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety, Tolerability, Pharmacokinetic (PK), and Pharmacodynamic Study of GSK2881078 and Study to Evaluate the Effect of CYP3A4 Inhibition on PK of GSK2881078

NCT02567773
View directory record Official record
Conditions
Cachexia
Interventions
GSK2881078, Placebo, Itraconazole
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 75 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 21, 2026, 2:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients

NCT00994669
View directory record Official record
Conditions
Cachexia
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
30 Years to 85 Years · Male only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2015 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain Function

NCT02460783
View directory record Official record
Conditions
Alzheimer's Disease, Obesity, Diabetes Mellitus
Interventions
Boost (R) 5-2 diet, Healthy Living Diet
Other
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 70 Years
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of LY3541105 in Healthy and Overweight Participants

NCT05380323
View directory record Official record
Conditions
Overweight, Healthy
Interventions
LY3541105, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
21 Years to 65 Years
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Lenexa, Kansas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 21, 2026, 2:37 PM EDT
Completed No phase listed Observational

The Impact of the COVID-19 Pandemic on Eating Behavior and Weight Change

NCT04896060
View directory record Official record
Conditions
COVID-19, Obesity
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 99 Years
Enrollment
5,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Recruiting No phase listed Observational

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

NCT06802861
View directory record Official record
Conditions
Preeclampsia, Preeclampsia (PE), Preeclampsia (PE) Risk, Obesity and Obesity-related Medical Conditions, Pregnancy, Pregnancy Complications, Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy, Gestational Complications
Interventions
Not listed
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 21, 2026, 2:37 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)

NCT06286761
View directory record Official record
Conditions
Obesity
Interventions
endothelial cell collection
Other
Lead sponsor
Bettina Mittendorfer
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional

Integrated Child Obesity Treatment Study: Bull City Healthy and Fit

NCT02573142
View directory record Official record
Conditions
Childhood Obesity
Interventions
Bull City Healthy and Fit, Healthy Lifestyles Clinic
Behavioral
Lead sponsor
Duke University
Other
Eligibility
5 Years to 11 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Oct 21, 2026, 2:37 PM EDT
Withdrawn Not applicable Interventional

Internet-Based Weight-Loss Program for Colorectal Cancer Survivors

NCT01032590
View directory record Official record
Conditions
Cancer Survivor, Colorectal Cancer, Weight Changes
Interventions
Internet weight loss intervention
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
2
States / cities
New Brunswick, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Phase 1 Interventional Results available

Study To Evaluate The Effect Of Two Steady State Doses of PF 06882961 On Rosuvastatin And Midazolam Pharmacokinetics In Otherwise Healthy Adult Participants With Obesity

NCT04621227
View directory record Official record
Conditions
Obesity
Interventions
PF-06882961, Rosuvastatin, Midazolam
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 21, 2026, 2:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%

NCT00714870
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Behavioral nutrition and exercise program
Behavioral
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
10 Years to 20 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 31, 2013 · Synced Oct 21, 2026, 2:37 PM EDT