Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:09 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 369 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Bone Mass Clear all

Conditions: Prostate Cancer
Interventions: Zometa; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 261 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 56
States / cities: Birmingham, Alabama • Anchorage, Alaska • Anaheim, California + 50 more

Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: Salmeterol 50 mcg BID, Fluticasone Propionate/Salmeterol 250/50 mcg BID, DISKUS inhaler; Drug · Device
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 40 Years and older
Enrollment: 186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 37
States / cities: Berkeley, California • Fullerton, California • Rancho Mirage, California + 31 more

Conditions: Knee Arthropathy
Interventions: Cement, Cementless, Manual Surgery, Robotic Surgery; Procedure · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 55 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Weight Gain, Disorder of Bone Density and Structure, Unspecified, Uterine Bleeding
Interventions: Depot medroxyprogesterone acetate (DMPA); Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 12 Years to 21 Years · Female only
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Osteoporosis, Frailty
Interventions: DHEA, Yoga, Placebo, Aerobics; Dietary Supplement · Behavioral
Lead sponsor: National Aeronautics and Space Administration (NASA); Federal
Eligibility: 65 Years and older · Female only
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Osteoporosis, Bone Loss, Age Related, Postmenopausal Bone Loss, Postmenopausal Osteoporosis
Interventions: Osteoporosis Choice Decision Aid; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 50 Years to 90 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Weight Loss
Interventions: Caloric restriction, high protein, Caloric restriction; normal protein, Nutrition Education; Behavioral
Lead sponsor: Rutgers University; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Postmenopausal, Osteopenia, Rheumatoid Arthritis, Osteoporosis
Interventions: Etanercept, Denosumab; Drug
Lead sponsor: Amgen; Industry
Eligibility: 45 Years to 80 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Duncansville, Pennsylvania • Dallas, Texas

Conditions: Asthma, Bone Density, Low, Oral Steroid-Dependent Asthma (Disorder)
Interventions: CT Scan, DXA Scan, Steroid Intake Questionnaire; Radiation · Other
Lead sponsor: University of Iowa; Other
Eligibility: 25 Years to 45 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Osteoporosis, Bone Loss, Osteopenia, Osteoporosis, Spinal Cord Injuries, Chronic Spinal Paralysis
Interventions: Romosozumab, Alendronate; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Osteoporosis
Interventions: Teriparatide, Alendronate, Calcium, Vitamin D3; Drug · Dietary Supplement
Lead sponsor: Helen Hayes Hospital; Other
Eligibility: 45 Years to 85 Years · Female only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2017
U.S. locations: 1
States / cities: West Haverstraw, New York

Conditions: Primary Hyperparathyroidism, Vitamin D Deficiency
Interventions: 10,000 IU Vitamin D3, Placebo, Vitamin D; Drug · Other · Dietary Supplement
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Lactational Amenorrhea, Body Weight Changes, Bone Loss
Interventions: Exercise and dietary; Other
Lead sponsor: North Carolina Agriculture & Technical State University; Other
Eligibility: 25 Years to 40 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Greensboro, North Carolina

Conditions: Osteogenesis Imperfecta
Interventions: Denosumab; Drug
Lead sponsor: Amgen; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 13
States / cities: Los Angeles, California • Torrance, California • Aurora, Colorado + 10 more

Conditions: Osteoporosis, Hypomagnesemia
Interventions: EffCaMgCit, Placebo; Drug · Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 21 Years to 99 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Osteoporosis
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Aortopathies, Thoracic Aortic Aneurysm, Aortic Valve Disease, Thoracic Aortic Disease, Thoracic Aortic Dissection, Thoracic Aortic Rupture, Ascending Aortic Disease, Descending Aortic Disease, Ascending Aortic Aneurysm, Descending Aortic Aneurysm, Marfan Syndrome, Loeys-Dietz Syndrome, Vascular Ehlers-Danlos Syndrome, Shprintzen-Goldberg Syndrome, Turner Syndrome, PHACE Syndrome, Autosomal Recessive Cutis Laxa, Congenital Contractural Arachnodactyly, Arterial Tortuosity Syndrome, Bicuspid Aortic Valve-Associated Aortopathy, Bicuspid Aortic Valve, Familial Thoracic Aortic Aneurysm and Aortic Dissection
Interventions: Not listed
Lead sponsor: Yale University; Other
Eligibility: Not listed
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2030
U.S. locations: 2
States / cities: Atlanta, Georgia • Indianapolis, Indiana

Conditions: Osteoporosis
Interventions: Diet with increased fruits, vegetables, and calcium, Increased high impact activity and resistance training; Behavioral
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 14 Years to 16 Years · Female only
Enrollment: 228 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2003
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Osteopenia
Interventions: Calcium Carbonate, Vitamin D3, Risedronate, Bone-loading exercises; Drug · Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older · Female only
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: HIV, Osteoporosis
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 99 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Osteoporosis
Interventions: Hormone replacement therapy, Strength training; Drug · Procedure
Lead sponsor: University of Arizona; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995 – 2001
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Bone Strength, Bone Density, FHA (Functional Hypothalamic Amenorrhea)
Interventions: transdermal 17β-E2 with cyclic progestin, oral 17β-E2 with cyclic progestin, transdermal EE+LNG; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 14 Years to 30 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 2
States / cities: Charlottesville, Virginia

Conditions: Diabetes Mellitus, Type 2
Interventions: Semaglutide; Drug
Lead sponsor: Emory University; Other
Eligibility: 65 Years and older · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Hypogonadism, Gender Identity Dysphoria
Interventions: Fortesta, Estradiol; Drug
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

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Open-label Trial on the Effect of I.V. Zoledronic Acid 4 mg on Bone Density in Hormone Sensitive Prostate Cancer Patients With Bone Metastasis

Bone Mineral Density Study In Patients With Chronic Obstructive Pulmonary Disease. DISKUS® Inhaler is a Trademark of the GSK Group of Companies.

Femoral BMD Change Following Cemented or Cementless Total Knee Arthroplasty

Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects

Effects of DHEA/Exercise on Bone, Muscle and Balance

Osteoporosis Choice Decision Aid for Use of Bisphosphonates in Postmenopausal Women

The Effect of Severe Weight Loss and Protein Intake on Bone

Effects of Denosumab on the Pharmacokinetics of Etanercept

CT-Based Changes in Bone and Marrow Among Patients on Oral Steroids

Romosozumab in Women With Chronic SCI

Cyclic Versus Daily Teriparatide on Bone Mass

Vitamin D Repletion in Primary Hyperparathyroidism

Effects of Exercise and Yogurt on Bone Mineral Density and Immunological Factors in Human Milk: The MEEMA Study

Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI

Averting Complications of Proton Pump Inhibitor Therapy by Effervescent Calcium Magnesium Citrate

Bone Mineral Density in HIV+ Patients

Pathogenetic Basis of Aortopathy and Aortic Valve Disease

Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study

Heartland Osteoporosis Prevention Study

Fracture and Bone Mineral Density in HIV+ Patients Recently Started on Antiretroviral Therapy (ART)

Bone Estrogen Strength Training

Role of Estrogen on Skeletal Outcomes in FHA

Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes

The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population