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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Connectivity Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease

NCT02380573
View directory record Official record
Conditions
Mild Cognitive Impairment, MCI, Aging, Alzheimer's Disease, AD
Interventions
Methylene Blue, FD&C Blue # 2, Phenazopyridine hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
45 Years to 89 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder

NCT00596622
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Lithium
Drug
Lead sponsor
Indiana University
Other
Eligibility
15 Years to 60 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 16, 2016 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Not applicable Interventional

Exercise for Memory Rehabilitation in Epilepsy

NCT04959019
View directory record Official record
Conditions
Epilepsy, Generalized, Memory Impairment
Interventions
Supervised combined endurance and resistance training (CERT), Delayed supervised combined endurance and resistance training (CERT)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Withdrawn No phase listed Observational

Attentional Performance in Parkinson Disease

NCT04428931
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
35 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Sep 10, 2026, 3:12 PM EDT
Withdrawn No phase listed Observational

Imaging of Brain Structural/Functional Connectivity and Amyloid and Tau Lesions in APOE4 Carriers.

NCT03816228
View directory record Official record
Conditions
Alzheimer Disease
Interventions
F 18 T807 Flortaucipir
Drug
Lead sponsor
Tammie L. S. Benzinger, MD, PhD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 10, 2026, 3:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Function in Performance of Motor Tasks

NCT00498329
View directory record Official record
Conditions
Brain Connectivity
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 10, 2026, 3:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sensory and Connectivity Abnormalities in Autism Spectrum Disorders

NCT00956579
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 32 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Not applicable Interventional Results available

Brain Connectivity and Response to Tai Chi in Geriatric Depression

NCT02460666
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Tai-Chi-Chih (TCC), Health Education and Wellness Classes (HEW)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Not applicable Interventional Results available

Establishing a Dose-response Relationship With Accelerated Transcranial Magnetic Stimulation

NCT04243798
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Active TBS-DLPFC, Sham TBS-DLPFC
Device
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users

NCT03341078
View directory record Official record
Conditions
Methamphetamine-dependence
Interventions
Ibudilast, Placebo Oral Tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Recruiting Not applicable Interventional

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

NCT05299749
View directory record Official record
Conditions
Schizophrenia, Auditory Hallucination, Treatment-resistant Schizophrenia
Interventions
stg-rt-fMRI-Neurofeeback, sham-rt-fMRI-Neurofeedback
Other
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Brockton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 10, 2026, 3:12 PM EDT
Withdrawn Not applicable Interventional

Precision Brain Mapping to Predict and Track Response to Exposure and Response Prevention Therapy in Youth With Obsessive-Compulsive Disorder

NCT07570108
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and Response Prevention Therapy, Clinical Assessments, Research MRI Sessions
Behavioral · Other · Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
10 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation for BECTS

NCT04325282
View directory record Official record
Conditions
Benign Epilepsy With Centrotemporal Spikes, Language Problems, Learning Disorders
Interventions
Active rTMS, Sham rTMS
Device
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 10, 2026, 3:12 PM EDT
Recruiting Not applicable Interventional

Stimulation-Induced Changes in Fronto-Limbic Network

NCT05854160
View directory record Official record
Conditions
Epilepsy, Mental Disorders
Interventions
Electrical Pulse Train Stimulation
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Not applicable Interventional

Examining Bladder Control Using Mindful Based Approach

NCT01843543
View directory record Official record
Conditions
Urinary Urgency Incontinence
Interventions
Mindfulness Based Stress Reduction Course
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 85 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 10, 2026, 3:12 PM EDT
Terminated Not applicable Interventional

Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease

NCT02232958
View directory record Official record
Conditions
Encephalopathy, White Matter Hyperintensities, Impaired Oxygen Delivery
Interventions
Hyperbaric Oxygen Treatment
Other
Lead sponsor
St. Luke's Hospital, Chesterfield, Missouri
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Chesterfield, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 29, 2017 · Synced Sep 10, 2026, 3:12 PM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy, a Mindfulness-Based Approach for Treatment of Chronic Musculoskeletal Pain

NCT04502992
View directory record Official record
Conditions
Chronic Musculoskeletal Disease
Interventions
Acceptance and Committment Therapy
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Sep 10, 2026, 3:12 PM EDT
Not listed No phase listed Observational

Advanced MRI In Acute Military TBI

NCT01313130
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 10, 2026, 3:12 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Connectivity Analysis for Investigation of Auditory Impairment in Epilepsy

NCT01212068
View directory record Official record
Conditions
Brain Mapping, Intracranial Central Nervous System Disorder, Epilepsy, Auditory Perceptual Disorder, Hearing Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 10, 2026, 3:12 PM EDT
Recruiting Not applicable Interventional

Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)

NCT06345963
View directory record Official record
Conditions
Schizophrenia
Interventions
active H-coil delivered rTMS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Completed No phase listed Observational

The Influence of in Utero Cannabis Exposure on Neonatal Brain Morphology and Structural Connectivity

NCT03718520
View directory record Official record
Conditions
Cannabis Use Disorder, PREG1, Drug Use, Fetal Exposure During Pregnancy, Neurodevelopmental Abnormality
Interventions
no intervention, this is a purely observational study
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older · Female only
Enrollment
168 participants
Timeline
2018 – 2020
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Sep 10, 2026, 3:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Role of Dopamine in Motor Learning in Healthy Subjects and Patients With Parkinson's Disease

NCT00032812
View directory record Official record
Conditions
Parkinson Disease, Healthy
Interventions
Raclopride
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 10, 2026, 3:12 PM EDT
Recruiting Not applicable Interventional

Ultrasound Neuromodulation in Essential Tremor

NCT06610877
View directory record Official record
Conditions
Essential Tremor, Neuromodulation
Interventions
Focused Ultrasound Neuromodulation - Sham Control, Focused ultrasound neuromodulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 10, 2026, 3:12 PM EDT
Completed No phase listed Observational

Event Related Potentials in Infants and Adults

NCT00088712
View directory record Official record
Conditions
Healthy, Child Development
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
3 Months to 45 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 10, 2026, 3:12 PM EDT