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Showing 1–24 of 90 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Health Activities Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Multidimensional Behavioral Intervention for Those at Risk for Alzheimer's Dementia

NCT03549078
View directory record Official record
Conditions
Functional Aging, Subjective Cognitive Concerns, Compensation Strategies, Brain Health Activities
Interventions
Intervention
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
65 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Jul 21, 2026, 5:31 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Hydrate Heroes for Improving Brain Function & Mood

NCT07241260
View directory record Official record
Conditions
Hydration Status
Interventions
Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Children's Cognitive and Brain Health Through Physical Activity Training (FITKids2)

NCT01619826
View directory record Official record
Conditions
Cognitive Ability, General, Achievement
Interventions
Physical Activity
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
8 Years to 9 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
4
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Jul 21, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

NCT05414708
View directory record Official record
Conditions
PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder, Posttraumatic Stress Disorder, Delayed Onset, Sleep Disturbance, Nightmare, Irritable Mood, Anger, Combat and Operational Stress Reaction, Combat Stress Disorders, Military Family, Military Operations, Emotional Regulation, Emotion Processing
Interventions
Art Therapy
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Regulation Training and Exercise Trial

NCT03124667
View directory record Official record
Conditions
Patient Compliance
Interventions
Games, Videos
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
35 Years to 64 Years
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

aeRobic Exercise and Cognitive Health

NCT02384993
View directory record Official record
Conditions
Alzheimer's Disease, Aging
Interventions
Enhanced Physical Activity
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Influence of Fitness on Brain and Cognition

NCT00438347
View directory record Official record
Conditions
Aging, Cognitive Ability, General
Interventions
Aerobic Exercise, Stretching and toning
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
60 Years to 75 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
2
States / cities
Champaign, Illinois • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 7, 2016 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality Study - COVID-19 Protocol

NCT04678778
View directory record Official record
Conditions
Healthy Aging
Interventions
Physical and Cognitive Activity
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Jul 21, 2026, 5:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Determining How Indoor Lighting Affects the Brain Health of Older Adults

NCT05978934
View directory record Official record
Conditions
Sleep, Physical Activity, Cognitive Function, Social Isolation
Interventions
Static Lighting Condition (L1), Dynamic Lighting Condition (L2), Dynamic Lighting Condition (L3)
Behavioral
Lead sponsor
Well Living Lab, Inc.
Industry
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cereset Research Long-Term Healthcare Worker Study

NCT05994261
View directory record Official record
Conditions
Stress, Anxiety, Autonomic Dysregulation, Acoustic Stimulation, Hyperarousal, Health Personnel
Interventions
Cereset Research
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 100 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI)

NCT05009524
View directory record Official record
Conditions
MCI, Mild Cognitive Impairment, Alzheimer Disease, Dementia
Interventions
iPACES (interactive Physical and Cognitive Exercise System), PACE (Physical and Cognitive Exercise)
Device
Lead sponsor
iPACES LLC
Industry
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton Park, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2021 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Endocannabinoids for Brain and Mental Health

NCT06808490
View directory record Official record
Conditions
Children, Adolescents
Interventions
Moderate Intensity Exercise, Light Intensity Stretching, Seated Meditation
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
9 Years to 17 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Developing Personalized Medicine Strategies to Increase Physical Activity in Parkinson's Disease (PD) Through Digital Health Technology

NCT05529121
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
40 Years to 89 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

B-Fit Intervention to Improve Brain Health

NCT03454074
View directory record Official record
Conditions
Health Behavior, Aging
Interventions
Problem-solving, Education
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
40 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Pullman, Washington
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Smart Trainer Arm Ergometry Exercise Training in Individuals Post-Stroke

NCT05410600
View directory record Official record
Conditions
Stroke
Interventions
Arm ergometer smart trainer cycling program
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Homewood, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Telehealth Pilot for Veterans with Chronic Multi-Symptom Illness.

NCT04164667
View directory record Official record
Conditions
Chronic Multisymptom Illness
Interventions
Mental and physical (MAP) training intervention
Behavioral
Lead sponsor
War Related Illness and Injury Study Center
Federal
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 3, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Results available

Socially Assistive Robots for Interaction With Older Adults With Dementia

NCT04384978
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Play Serious Games with a Social Robot (Ryan), Play Solitary Games Without a Social Robot
Behavioral
Lead sponsor
DreamFace Technologies, LLC
Industry
Eligibility
65 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lakewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

SAGE LEAF 2: An Online Program to Reduce Dementia Caregiver Burden

NCT06708182
View directory record Official record
Conditions
Caregiving Stress, Caregiver Burden
Interventions
SAGE LEAF Positive Emotion Skills Course
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Exercise Effects on Cognition in School-Aged Children

NCT01334359
View directory record Official record
Conditions
Brain Health, Cognition, Scholastic Achievement
Interventions
Physical Activity
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
8 Years to 9 Years
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Lakeshore Examination of Activity and Disability Exercise Response Study

NCT02533882
View directory record Official record
Conditions
Multiple Sclerosis, Stroke
Interventions
Movement to Music, Adapted Yoga
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 3 Interventional

Stroke Inpatient Rehabilitation Reinforcement of ACTivity

NCT01246882
View directory record Official record
Conditions
Stroke
Interventions
Augmented activity feedback, Speed-only feedback
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
5
States / cities
Worcester, Massachusetts • Rochester, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Hispanic Secondary Stroke Prevention Initiative

NCT02251834
View directory record Official record
Conditions
Stroke
Interventions
Community Health Worker (CHW), usual care and health education brochures every 4 months.
Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated Not applicable Interventional Results available

Exercise Training to Improve Brain Health in Older HIV+ Individuals

NCT02663934
View directory record Official record
Conditions
HIV
Interventions
Exercise, Stretching and Social Interaction
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Aerobic Exercise and Cerebrovascular Function

NCT03803904
View directory record Official record
Conditions
Aging
Interventions
Spin
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 21, 2026, 5:31 PM EDT