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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Injuries, Traumatic Clear all
Completed No phase listed Observational

Exoskeleton Rehabilitation on TBI

NCT04465019
View directory record Official record
Conditions
Traumatic Brain Injury, Cerebral Stroke
Interventions
Exoskeleton Rehabilitation
Device
Lead sponsor
DHR Health Institute for Research and Development
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Edinburg, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Prevention of Traumatic Brain Injury in Youth and Adolescents

NCT01629121
View directory record Official record
Conditions
Focus of Study: Bicycle Helmet Wearing Compliance
Interventions
education intervention
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
5 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Jul 21, 2026, 11:24 AM EDT
Not listed Not applicable Interventional

Strategy + RehaCom for Memory Rehabilitation in Traumatic Brain Injury (TBI)

NCT04239456
View directory record Official record
Conditions
Traumatic Brain Injury With Loss of Consciousness
Interventions
RehaCom (software)
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Telephone Intervention After Traumatic Brain Injury

NCT00483522
View directory record Official record
Conditions
Brain Injuries
Interventions
Self-management telephone counseling
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
16 Years and older
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
3
States / cities
Jackson, Mississippi • Philadelphia, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 19, 2012 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

Light Therapy for Moderate Traumatic Brain Injury

NCT02233413
View directory record Official record
Conditions
Moderate Traumatic Brain Injury (TBI)
Interventions
Active LLLT helmet application, Non-active LLLT helmet application
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jul 21, 2026, 11:24 AM EDT
Not listed Phase 1 Interventional

Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Traumatic Brain Injury

NCT00594503
View directory record Official record
Conditions
Residual Neurological, Cognitive, Emotional, Behavioral Effects From Traumatic Brain Injury
Interventions
Hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion

NCT02710123
View directory record Official record
Conditions
Brain Injury, Concussion
Interventions
Sub-Threshold exercise prescription, Structured stretching prescription
Other
Lead sponsor
University at Buffalo
Other
Eligibility
10 Years to 18 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 21, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

NCT07385105
View directory record Official record
Conditions
Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions
Cognitive behavioral Therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Deep Brain Stimulation for Traumatic Brain Injury

NCT01277952
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Ali Rezai, MD
Other
Eligibility
20 Years to 60 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Jul 21, 2026, 11:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Is Y-Balance Test Predictive of Concussion

NCT05344703
View directory record Official record
Conditions
Concussion, Brain, Concussion; Eye
Interventions
Y Balance Plus Visual Perturbations, Y balance
Device · Diagnostic Test
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
11 Years to 19 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jul 21, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury

NCT07436754
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Alexithymia
Interventions
Program 1, Program 2
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Indianapolis, Indiana • Bethesda, Maryland • Edison, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation:ACTION Training for Soldiers With Executive Dysfunction

NCT02352441
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Implementation Intentions(II)
Other
Lead sponsor
Allina Health System
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 10, 2018 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Phase 4 Interventional Results available

Beta Blockade in in Traumatic Brain Injury

NCT02957331
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Propranolol
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Jul 21, 2026, 11:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients

NCT05622786
View directory record Official record
Conditions
Traumatic Brain Injury, Gait Disorders, Neurologic
Interventions
HIGT - physical rehab, Low intensity physical therapy
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Jul 21, 2026, 11:24 AM EDT
Completed No phase listed Observational

Traumatic Brain Injury Among Homeless Veterans

NCT01120054
View directory record Official record
Conditions
Traumatic Brain Injury, Homelessness
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
3
States / cities
Denver, Colorado • Tampa, Florida • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Jul 21, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

NCT06413173
View directory record Official record
Conditions
Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment, Post Concussive Symptoms
Interventions
Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
Combination Product
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
San Diego, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 21, 2026, 11:24 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)

NCT05823766
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Epilepsy
Interventions
In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Clinical Visit, Blood Draw, EEG, Telephone Outcome Assessment
Behavioral · Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
9
States / cities
San Francisco, California • Charlestown, Massachusetts • Cincinnati, Ohio + 6 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 21, 2026, 11:24 AM EDT
Terminated Phase 3 Interventional Results available

Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

NCT00983437
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Armodafinil
Drug
Lead sponsor
Cephalon, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
61
States / cities
Birmingham, Alabama • Tucson, Arizona • Hot Springs, Arkansas + 49 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

NCT02266329
View directory record Official record
Conditions
Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache, Mild Traumatic Brain Injury, Posttraumatic Migraine
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 11:24 AM EDT
Terminated Phase 2 Interventional

Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI

NCT02148783
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
methylphenidate, Placebo
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

Acute Neurobehavioral Program for Improving Functional Status After TBI

NCT01166386
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
FANCI
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Functional Near-Infrared Spectroscopy (fNIRS) Assessing Neural Activity During Virtual Reality Walking Intervention

NCT06276894
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Motek C-Mill™ treadmill, training session with and without VR wearing the fNIRS cap
Device · Other
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 11:24 AM EDT
Recruiting Phase 2 Interventional

Hyperbaric Oxygen Brain Injury Treatment Trial

NCT02407028
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Hyperbaric oxygen (1.5 ATA, no NBH), Hyperbaric oxygen (2.0 ATA, no NBH), Hyperbaric oxygen (2.5 ATA, no NBH), Hyperbaric oxygen (1.5 ATA + NBH), Hyperbaric oxygen (2.0 ATA + NBH), Hyperbaric oxygen (2.5 ATA + NBH), Normobaric Hyperoxia (NBH), Usual Care
Drug · Other
Lead sponsor
Gaylan Rockswold
Other
Eligibility
16 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2029
U.S. locations
10
States / cities
San Diego, California • West Palm Beach, Florida • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health

NCT04641832
View directory record Official record
Conditions
Concussion, Mild
Interventions
Soccer heading
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 26 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Jul 21, 2026, 11:24 AM EDT