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ClinicalTrials.gov public records Last synced Nov 5, 2026, 2:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 1,430 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Brain Stimulation Clear all

Conditions: Phantom Limb Pain
Interventions: transcranial Direct Current Stimulation (tDCS): (Soterix ©); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Dystonia, Generalized Primary Dystonia
Interventions: Deep Brain Stimulation; Procedure
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 7 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Treatment Resistant Depression
Interventions: Medtronic SenSight Directional DBS lead; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2038
U.S. locations: 1
States / cities: Queens, New York

Conditions: Ischemic Stroke, Upper Extremity Problem
Interventions: Vivistim System; Device
Lead sponsor: MicroTransponder Inc.; Industry
Eligibility: 19 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Dystonia, Focal Dystonia, Cerebellar Disease
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 85 Years
Enrollment: 47 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Stroke, Motor Function
Interventions: Active Repetitive Transcranial Magnetic Stimulation (rTMS), Fluoxetine, Sham repetitive transcranial magnetic stimulation (rTMS), Placebo Fluoxetine; Device · Drug
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Tinnitus
Interventions: Burst-SCS/sham SCS, Sham SCS/Burst-SCS; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Healthy
Interventions: Transcranial electrical stimulation (TES), Transcranial electrical stimulation with temporal interference (TES-TI), Sham stimulation; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 80 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Mild Dementia, Aging Well
Interventions: Neurolith Transcranial Pulse Stimulation Active, Neurolith Transcranial Pulse Stimulation Sham; Device
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 84 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Alzheimer Disease, Family Members
Interventions: GENUS; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 55 Years to 90 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts • Cambridge, Massachusetts

Conditions: Smoking, Nicotine Dependence, Addiction, Smoking, Cigarette
Interventions: Real cTBS, Sham cTBS; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Metastatic Malignant Neoplasm in the Brain, Radiation Therapy Recipient
Interventions: Hand Function Test, Navigated Transcranial Magnetic Stimulation, Quality-of-Life Assessment, Questionnaire Administration; Behavioral · Procedure · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cannabis Use Disorder
Interventions: Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS), Mindfulness meditation; Device · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 22 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury, Headache, Dizziness, Cognitive Symptom, Dysautonomia, Anxiety, Irritability; Syndrome, Depression, Post-traumatic Stress Disorder
Interventions: Active cTBS, Inactive/Sham cTBS, Imaginal exposure; Device · Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Westwood, Los Angeles, California

Conditions: Stroke, Arm Weakness as a Consequence of Stroke, Upper Extremity Hemiparesis, Upper Extremity Impairments, Upper Extremity Weakness
Interventions: Low intensity focused ultrasound stimulation; Device
Lead sponsor: Duke University; Other
Eligibility: 21 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Essential Tremor, Deep Brain Stimulation
Interventions: Alternating stimulation, Placebo; Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Epilepsy
Interventions: AMSCs; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Parkinson Disease
Interventions: Neurophysiology recordings, Neural stimulation; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Healthy Adult Participants, Healthy Participants
Interventions: Magnetic Resonance Imaging (MRI), Broad thalamic stimulation (TI-TES), Carrier only SHAM stimulation, Anterior thalamic stimulation (TI-TES), Posterior thalamic stimulation (TI-TES); Other · Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: active anodal tDCS, sham tDCS; Device
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 55 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Richardson, Texas

Conditions: Parkinson Disease
Interventions: Gen0Bh Transcranial Focused Ultrasound System (Active), Gen0Bh Transcranial Focused Ultrasound System (Sham); Device
Lead sponsor: Sanmai Technologies PBC dba Sanmai; Industry
Eligibility: 22 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: Tucson, Arizona • Santa Monica, California • Gainesville, Florida + 1 more

Conditions: Migraine Disorders
Interventions: gammaCore Sapphire active, gammaCore Sapphire Sham; Device
Lead sponsor: ElectroCore INC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 231 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 30
States / cities: Scottsdale, Arizona • Carlsbad, California • Palo Alto, California + 27 more

Conditions: Stroke
Interventions: repetitive transcranial magnetic stimulation (rTMS), peripheral sensory stimulation; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Parkinson's Disease
Interventions: Cranial Electric Stimulation (CES), Treadmill, CES and Treadmill; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

Predicting Pain Response to Transcranial Direct Current Stimulation for Phantom Limb Pain in Limb Amputees

Deep Brain Stimulation for Cervical Dystonia

DBS for Depression

VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home

Brain Changes in Blepharospasm

Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients

Reversing Synchronized Brain Circuits With Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

Transcranial Pulse Stimulation of the Brain

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

Nicotine TMS EFT Smoking Pilot Study

nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients

Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

Location- and Frequency-Dependent Effects of Thalamic Temporal Interference Stimulation During Sleep

Stimulating the Brain to Improve Self-Awareness

Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines

Can rTMS Enhance Somatosensory Recovery After Stroke?

Transcranial Direct Current Stimulation (tDCS) and Parkinson's Disease