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ClinicalTrials.gov public records Last synced Oct 9, 2026, 6:59 PM EDT

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Showing 49–72 of 148 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Bronchopulmonary Dysplasia of Newborn Clear all
Completed Not applicable Interventional Results available

Impact of CPAP Level on V/Q Mismatch in Premature Infants

NCT02983825
View directory record Official record
Conditions
Infant, Premature, Diseases, Respiratory Insufficiency Syndrome of Newborn
Interventions
Continuous positive airway pressure (CPAP); level changes
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
24 Hours to 35 Weeks
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Oct 9, 2026, 6:59 PM EDT
Completed No phase listed Observational

Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD

NCT04107701
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease of Newborn, Environmental Exposure
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 12 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 9, 2026, 6:59 PM EDT
Terminated Not applicable Interventional Results available

Prone Versus Supine Positioning and the Impact on Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.

NCT04890158
View directory record Official record
Conditions
Prone Positioning, Bronchopulmonary Dysplasia
Interventions
Prone positioning for a total of 6 hours daily
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
7 Days to 14 Weeks
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 9, 2026, 6:59 PM EDT
Terminated Early Phase 1 Interventional Results available

L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia

NCT03542812
View directory record Official record
Conditions
Infant,Premature, Bronchopulmonary Dysplasia, Pulmonary Hypertension
Interventions
L-Citrulline
Drug
Lead sponsor
University of Utah
Other
Eligibility
14 Days to 3 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 9, 2026, 6:59 PM EDT
Recruiting Phase 2 Interventional

Lipid Infusions to Optimize Nutrition Trial

NCT06915441
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Neurodevelopmental Impairment
Interventions
SOLE, MOLE
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Hours to 28 Weeks
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 9, 2026, 6:59 PM EDT
Terminated Phase 1 Interventional Results available

A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for BPD

NCT03857841
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
UNEX-42, Phosphate-buffered saline
Biological
Lead sponsor
United Therapeutics
Industry
Eligibility
3 Days to 14 Days
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
6
States / cities
Aurora, Colorado • Boston, Massachusetts • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Not applicable Interventional

A Study of Tobacco Smoke and Children With Respiratory Illnesses

NCT03062709
View directory record Official record
Conditions
Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma, Tobacco Smoking, Tobacco Cessation, Bronchopulmonary Dysplasia
Interventions
Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
Behavioral · Diagnostic Test
Lead sponsor
MaineHealth
Other
Eligibility
Up to 10 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Oct 9, 2026, 6:59 PM EDT
Active, not recruiting No phase listed Observational

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

NCT03782610
View directory record Official record
Conditions
Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia, Neurodevelopmental Abnormality
Interventions
Not listed
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 72 Hours
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
4
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Not applicable Interventional Results available

Transfusion of Prematures Trial

NCT01702805
View directory record Official record
Conditions
Infant, Newborn, Diseases, Infant, Extremely Low Birth Weight, Infant, Small for Gestational Age, Bronchopulmonary Dysplasia (BPD), Anemia
Interventions
Liberal Cell Transfusion, Restricted red cell transfusion
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
1,824 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
20
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 9, 2026, 6:59 PM EDT
Terminated Phase 3 Interventional

Management of Hyponatremia in Preterm Infants on Diuretics

NCT00156572
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Hyponatremia on Diuretics
Interventions
Sodium supplementation, Fluid restriction
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
4 Weeks to 6 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2007 · Synced Oct 9, 2026, 6:59 PM EDT
Recruiting Not applicable Interventional

Continued Pressure for Alveolar Protection (CPAP Trial)

NCT07417111
View directory record Official record
Conditions
Bronchopulmonary Dysplasia (BPD)
Interventions
CPAP, Nasal Cannula
Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 31 Weeks
Enrollment
860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
15
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 9, 2026, 6:59 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Early Versus Expectant Treatment of Ureaplasma Infection in Very Low Birth Weight Neonates

NCT00599053
View directory record Official record
Conditions
Bacteria Infection, Respiratory Tract Infections
Interventions
Azithromycin
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 3 Days
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Not applicable Interventional

Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants

NCT05968586
View directory record Official record
Conditions
Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
Interventions
Body positioning
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Minute to 3 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Phase 1 Interventional

Seattle-PAP Bubble Nasal CPAP and Work of Breathing

NCT02210026
View directory record Official record
Conditions
Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia, Newborn Primary Sleep Apnea
Interventions
Seattle-PAP
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Hours to 72 Hours
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 9, 2026, 6:59 PM EDT
Recruiting Not applicable Interventional

Gastric Feeding Versus Transpyloric Feeding in Infants with Severe Bronchopulmonary Dysplasia, a Crossover Study

NCT06821776
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Feeding Intolerance
Interventions
Gastric feeding, Transpyloric feeding
Procedure
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
1 Month to 1 Year
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 9, 2026, 6:59 PM EDT
Completed No phase listed Observational

Neonatal Intensive Care (NICU) Course and Hospital Outcome of Infants With BPD Treated Using Inhaled Nitric Oxide

NCT00757146
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 28 Days
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 24, 2010 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Phase 3 Interventional Results available

Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia

NCT01022580
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Infasurf surfactant (ONY, Inc.), Sham (No Treatment)
Drug
Lead sponsor
Roberta Ballard
Other
Eligibility
7 Days to 14 Days
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
21
States / cities
Little Rock, Arkansas • Berkeley, California • Oakland, California + 15 more
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 9, 2026, 6:59 PM EDT
Withdrawn Phase 1 Interventional

Phase 1 Intravenous Citrulline for the Prevention of Bronchopulmonary Dysplasia in Preterm Infants

NCT00742534
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Intravenous L-Citrulline
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
2 Days to 14 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 30, 2011 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Not applicable Interventional Results available

Aerosolized Albuterol Use in Severe BPD

NCT02766673
View directory record Official record
Conditions
Severe Bronchopulmonary Dysplasia
Interventions
Albuterol Sulfate, Sterile Saline
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 1 Year
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 9, 2026, 6:59 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Pulmonary Function Using Non-invasive Forced Oscillometry

NCT03346343
View directory record Official record
Conditions
Infant, Premature, Diseases, Infant, Newborn, Diseases, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Newborn, Meconium Aspiration Syndrome, Transient Tachypnea of the Newborn
Interventions
Non-invasive forced airway oscillometry
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 2 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia

NCT04447989
View directory record Official record
Conditions
Bronchopulmonary Dysplasia of Newborn
Interventions
Sildenafil, Placebo
Drug
Lead sponsor
Christoph Hornik
Other
Eligibility
Up to 29 Weeks
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
25
States / cities
Little Rock, Arkansas • San Diego, California • Washington D.C., District of Columbia + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 9, 2026, 6:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Work of Breathing in Premature Infants at Discharge

NCT03682575
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Very Low Birth Weight Infant, Prematurity
Interventions
Enrollment
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
1 Month to 7 Months
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 9, 2026, 6:59 PM EDT
Completed Phase 4 Interventional

The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia

NCT00926276
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Bronchopulmonary Dysplasia
Interventions
Fundoplication
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
24 Weeks to 1 Year
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2014 · Synced Oct 9, 2026, 6:59 PM EDT
Recruiting Not applicable Interventional

Ventilator Pressure and Optimization of Compliance and Hemodynamics

NCT06512935
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Extreme Prematurity, Ventilator Lung; Newborn, Ventilation Perfusion Mismatch
Interventions
Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
7 Days to 30 Days
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 9, 2026, 6:59 PM EDT