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ClinicalTrials.gov public records Last synced Oct 6, 2026, 5:56 AM EDT

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Showing 25–48 of 94 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: CRPS (Complex Regional Pain Syndromes) Clear all
Completed Not applicable Interventional Results available

Virtual Reality Guided Imagery for Chronic Pain

NCT04849897
View directory record Official record
Conditions
Complex Regional Pain Syndromes, Back Pain
Interventions
Experimental: Virtual Reality Guided Imagery, Active Comparator: Audio Only Guided Imagery
Device · Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated Not applicable Interventional

Modulating Neuropathic Pain With Transcranial Direct Current Stimulation

NCT04581525
View directory record Official record
Conditions
Pain, Neuropathic, Complex Regional Pain Syndromes, Phantom Limb Pain, Spinal Cord Injuries
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Susan McDowell
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 6, 2026, 5:56 AM EDT
Recruiting Not applicable Interventional

Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients

NCT07791966
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
transcranial alternating current stimulation (tACS)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 6, 2026, 5:56 AM EDT
Completed No phase listed Observational

Evaluation and Diagnosis of People With Pain and Fatigue Syndromes

NCT00677157
View directory record Official record
Conditions
Fatigue
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years and older
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

Intraoperative Neuromonitoring Recording With a Novel SCS Paddle

NCT05045625
View directory record Official record
Conditions
Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
Interventions
HD Study Electrode
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Effects of Vaporized Marijuana on Neuropathic Pain

NCT01037088
View directory record Official record
Conditions
Neuropathic Pain, Reflex Sympathetic Dystrophy, Peripheral Neuropathy, Post-herpetic Neuralgia, Spinal Cord Injury, Multiple Sclerosis
Interventions
Mild dose cannabis, Low dose cannabis, Cannabis
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Phase 4 Interventional

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

NCT00904202
View directory record Official record
Conditions
Postherpetic Neuralgia, Diabetic Neuropathy, Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, HIV Neuropathy, Idiopathic Sensory Neuropathy, Peripheral Neuropathy
Interventions
Placebo Capsules + Placebo Patch, Placebo capsules + Lidoderm®, Gabapentin + Placebo, Gabapentin + Lidoderm®, Gabapentin 300 mg capsules 1800 mg/day + placebo patch, Gabapentin 1800 mg/day + Lidoderm patch
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
7
States / cities
Birmingham, Alabama • Hueytown, Alabama • Phoenix, Arizona + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated Phase 2 Interventional Results available

Neurotropin to Treat Chronic Neuropathic Pain

NCT00006289
View directory record Official record
Conditions
Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II
Interventions
Placebo, Neurotropin
Drug
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome

NCT02094352
View directory record Official record
Conditions
Complex Regional Pain Syndrome
Interventions
Ketamine Infusion + Epidural Infusion, Control Group + Epidural infusion, Ketamine Booster Infusion, Control Group Booster Infusion
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Oct 6, 2026, 5:56 AM EDT
Not listed Not applicable Interventional

Low-Intensity Focused Ultrasound For Insular Neuromodulation in Chronic Pain

NCT05751096
View directory record Official record
Conditions
Fibromyalgia, Complex Regional Pain Syndromes, Chronic Pain
Interventions
Low-intensity Focused Ultrasound (LIFU), Sham Low-intensity focused ultrasound (LIFU)
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 6, 2026, 5:56 AM EDT
Completed No phase listed Observational Results available

TARGET Post-Approval Study

NCT02800863
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System), Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
22 Years to 75 Years
Enrollment
426 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
44
States / cities
Scottsdale, Arizona • Camarillo, California • Larkspur, California + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Not applicable Interventional

Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults

NCT05888142
View directory record Official record
Conditions
Pain, Chronic
Interventions
in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated Not applicable Interventional

Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome

NCT00780390
View directory record Official record
Conditions
Complex Regional Pain Syndrome
Interventions
Autonomic Function Assessment
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 6, 2026, 5:56 AM EDT
Completed No phase listed Observational

Susceptibility to Chronic Post-Traumatic Extremity Pain

NCT00672711
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 6, 2026, 5:56 AM EDT
Suspended Phase 2 Interventional

Ketamine HCl Prolonged Release Oral Tablets for CRPS

NCT06419985
View directory record Official record
Conditions
Complex Regional Pain Syndromes
Interventions
80mg/day Ketamine HCl Prolonged Release, 160mg/day Ketamine HCl Prolonged Release
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 64 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 6, 2026, 5:56 AM EDT
Recruiting No phase listed Observational

Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain

NCT07639060
View directory record Official record
Conditions
Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain, Hip Osteoarthritis, Knee Osteoarthritis, Spasticity, Chronic Low Back Pain, Lumbar Spondylosis, Cervical Spondylosis, Shoulder Arthritis, Causalgia, Chronic Pain Syndrome, Chronic Neck Pain
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Old Saybrook, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome

NCT03762213
View directory record Official record
Conditions
Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy, Complex Regional Pain Syndromes
Interventions
Oculus GO VR HMD, application Happy Place (© Mimerse), iPad, application Happy Place (© Mimerse)
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
13 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)

NCT03560986
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
Neridronic acid 100 mg, Placebo
Drug
Lead sponsor
Grünenthal GmbH
Industry
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
41
States / cities
Cottonwood, Arizona • Tempe, Arizona • Tucson, Arizona + 34 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation (TMS) for CRPS

NCT02067273
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Study of Proteins Associated With Complex Regional Pain Syndrome

NCT00033969
View directory record Official record
Conditions
Complex Regional Pain Syndromes, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 6, 2026, 5:56 AM EDT
Terminated Phase 1 Interventional

Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.

NCT02321566
View directory record Official record
Conditions
Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II), Trigeminal Neuropathic Pain, Trigeminal Deafferentation Pain, Complex Regional Pain Syndrome (Types I and II, Involving the Upper Extremity), Glossopharyngeal Neuralgia, Upper Extremity Pain Due to Deafferentation of the Cervical Spine, Central Pain Syndromes
Interventions
Epidural Motor Cortex Stimulation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Not applicable Interventional

Immersive Virtual Reality for Neuropathic Pain

NCT03203772
View directory record Official record
Conditions
Neuropathy, Phantom Limb Pain, Complex Regional Pain Syndromes, Neuropathic Pain
Interventions
Immersive Virtual Reality
Other
Lead sponsor
Loma Linda University
Other
Eligibility
12 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 6, 2026, 5:56 AM EDT
Withdrawn No phase listed Observational

Predicting Pain Exacerbations in Children With Complex Regional Pain Syndrome (CRPS)

NCT06337526
View directory record Official record
Conditions
Complex Regional Pain Syndromes
Interventions
Apple Watch v8
Device
Lead sponsor
Stanford University
Other
Eligibility
8 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 6, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

TMS for CRPS - Pilot Study

NCT01926119
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 6, 2026, 5:56 AM EDT