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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Calcification Clear all
Active, not recruiting No phase listed Observational

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

NCT06302439
View directory record Official record
Conditions
Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency, ATP-Binding Cassette Subfamily C Member 6 Deficiency
Interventions
No Intervention for this observational study
Other
Lead sponsor
Inozyme Pharma
Industry
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • Boston, Massachusetts • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Not applicable Interventional Results available

Disrupt PAD+ Study With the Shockwave Medical M5+ Peripheral IVL System

NCT04585763
View directory record Official record
Conditions
Peripheral Arterial Disease, Vascular Disease, Peripheral
Interventions
Shockwave Medical M5+ Peripheral Intravascular Lithotripsy (IVL)
Device
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Davenport, Iowa • Raleigh, North Carolina • Bartlesville, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pharmacokinetic Analysis of Nutrient Absorption From a Novel Liposomal Multivitamin/Mineral Formulation

NCT05060367
View directory record Official record
Conditions
Mineral Absorption
Interventions
Liposomal multivitamin/mineral, Standard multivitamin/mineral
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Phase 2 Interventional Results available

Adding Phosphorus to Osteoporosis Drug Treatment

NCT00074711
View directory record Official record
Conditions
Osteoporosis, Osteopenia
Interventions
Calcium carbonate, Calcium Phosphate
Drug
Lead sponsor
Creighton University
Other
Eligibility
60 Years to 85 Years · Female only
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Sep 5, 2026, 5:26 PM EDT
Not yet recruiting Not applicable Interventional

ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former High-Intensity Athletes

NCT07460583
View directory record Official record
Conditions
Coronary Atherosclerosis Due to Calcified Coronary Lesion
Interventions
Coronary CTA
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
30 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Phase 4 Interventional Results available

Effect of Bisphosphonate on Bone Loss in Postmenopausal Women With Breast Cancer Initiating Aromatase Inhibitor Therapy

NCT00485953
View directory record Official record
Conditions
Bone Loss, Osteoporosis, Breast Cancer
Interventions
risedronate
Drug
Lead sponsor
Susan L. Greenspan
Other
Eligibility
55 Years and older · Female only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 5, 2026, 5:26 PM EDT
Not listed Phase 2 Interventional

Bisphosphonate Therapy for HIV-Infected Adults With Decreased Bone Mineral Density

NCT00102908
View directory record Official record
Conditions
HIV Infections, Osteopenia, Osteoporosis
Interventions
Zoledronate, Zoledronate placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2008 · Synced Sep 5, 2026, 5:26 PM EDT
Recruiting Not applicable Interventional

Bone Mineral Density Precision Study

NCT06830811
View directory record Official record
Conditions
Indicated for EOSedge Imaging
Interventions
EOSedge imaging
Radiation
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
20 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fishers, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 16, 2025 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Not applicable Interventional

Correlation Between Vitamin D Status and Bone Mineral Density in Patients With Hemophilia

NCT01090206
View directory record Official record
Conditions
Hemophilia A, Hemophilia B, Vitamin D Deficiency
Interventions
Vitamin D and calcium
Dietary Supplement
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
2 Years to 21 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Not applicable Interventional

A Study to Assess Metabolic Bone Disease of Prematurity Using an Acoustic Method

NCT04752098
View directory record Official record
Conditions
Metabolic Bone Disease, Osteopenia, Neonatal Rickets
Interventions
Vibro-acoustic analysis (VAA), based on ultrasound radiation force
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Days to 8 Months
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Phase 2 Interventional Results available

A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification

NCT02481258
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Ataciguat (HMR1766), Placebo Comparator: Matching Placebo
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Not applicable Interventional Results available

Effect of Thiazolidinediones on Human Bone

NCT00927355
View directory record Official record
Conditions
Osteoblast, Adipocytes, Bone Density, Osteocalcin, Adiponectin, Mesenchymal Stem Cells
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 28, 2016 · Synced Sep 5, 2026, 5:26 PM EDT
Terminated Phase 3 Interventional

Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria

NCT03847090
View directory record Official record
Conditions
Enteric Hyperoxaluria
Interventions
Reloxaliase, Placebo
Drug
Lead sponsor
Allena Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
64
States / cities
Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Sep 5, 2026, 5:26 PM EDT
Completed No phase listed Observational

Bone Metabolism After Bariatric Surgery

NCT01824797
View directory record Official record
Conditions
Obesity, Osteoporosis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
40 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2019 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Not applicable Interventional Results available

Disrupt CAD III With the Shockwave Coronary IVL System

NCT03595176
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Infarction
Interventions
Lithotripsy
Device
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
Not listed
Enrollment
431 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
39
States / cities
Scottsdale, Arizona • La Jolla, California • Orange, California + 32 more
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 5, 2026, 5:26 PM EDT
Completed No phase listed Observational

Fracture and Bone Mineral Density in HIV+ Patients Recently Started on Antiretroviral Therapy (ART)

NCT01591252
View directory record Official record
Conditions
HIV, Osteoporosis
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 1, 2016 · Synced Sep 5, 2026, 5:26 PM EDT
Terminated Phase 1 Interventional Results available

Effects of Denosumab on the Pharmacokinetics of Etanercept

NCT01294397
View directory record Official record
Conditions
Postmenopausal, Osteopenia, Rheumatoid Arthritis, Osteoporosis
Interventions
Etanercept, Denosumab
Drug
Lead sponsor
Amgen
Industry
Eligibility
45 Years to 80 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Duncansville, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 5, 2026, 5:26 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Vitamin and Mineral Absorption From Milk and PBMAs

NCT05898217
View directory record Official record
Conditions
Nutrition, Healthy
Interventions
Dairy Milk, Soy Milk, Almond Milk, Oat Milk
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
25 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 5, 2026, 5:26 PM EDT
Recruiting No phase listed Observational

Partners Calciphylaxis Biobank

NCT03032835
View directory record Official record
Conditions
Calciphylaxis, Calcific Uremic Arteriolopathy, End Stage Renal Disease, Chronic Kidney Diseases
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 5, 2026, 5:26 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Selenium Intervention on Inflammation in Older Adults

NCT01289925
View directory record Official record
Conditions
Inflammation
Interventions
Selenium, Sugar Pill Placebo
Dietary Supplement · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
70 Years to 110 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 8, 2018 · Synced Sep 5, 2026, 5:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Role of Impact Activity in Peripubertal Bone Accrual

NCT00619047
View directory record Official record
Conditions
Bone Mineral Density
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
10 Years to 12 Years · Female only
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2009 · Synced Sep 5, 2026, 5:26 PM EDT
Recruiting No phase listed Observational

CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions

NCT05145478
View directory record Official record
Conditions
Femoral Arterial Calcification, Peripheral Arterial Disease, Claudication, Critical Limb Ischemia
Interventions
Shockwave Intravascular Lithotripsy (IVL)
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 5, 2026, 5:26 PM EDT
Terminated Phase 2 Interventional Results available

Effect of VSL#3 on Bone Mineral Density in Postmenopausal Women

NCT03165747
View directory record Official record
Conditions
Menopausal Osteoporosis
Interventions
VSL#3, Placebo
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
50 Years to 65 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 5, 2026, 5:26 PM EDT
Completed Phase 2 Interventional Results available

Bone Mineral Density Effects of Zoledronate in Postmenopausal Women With Breast Cancer

NCT00213980
View directory record Official record
Conditions
Breast Cancer
Interventions
Zoledronate
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Sep 5, 2026, 5:26 PM EDT