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ClinicalTrials.gov public records Last synced Sep 27, 2026, 2:51 PM EDT

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Showing 1–24 of 233 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cancer Lung Screening Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Empowering Hispanic Patients' Lung Cancer Screening Uptake (Empower Latinx)

NCT06225414
View directory record Official record
Conditions
Lung Cancer
Interventions
Usual Care, Brief Patient Education, Patient education, Referral to financial navigation resources, Patient Reminders, Provider Reminders
Other · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
10
States / cities
Anaheim, California • Costa Mesa, California • Irvine, California + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Recruiting No phase listed Observational

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

NCT00242723
View directory record Official record
Conditions
Thoracic Cancers, Malignant Pleural Mesotheliomas NOS, Lung Cancer NOS, Esophageal Cancers NOS, Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura, Thoracic Malignancies
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
2 Years to 120 Years
Enrollment
1,559 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

NCT04798664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Removal of Financial Barriers, Financial Incentives, Mobile Health Application
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
3,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
Oakland, California • Detroit, Michigan • Danville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Awareness, Information, and Resources for Lung Cancer Screening Program for Community-Partnered Lung Cancer Screening

NCT04635761
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Educational Intervention, Questionnaire Administration
Behavioral
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Phase 4 Interventional Results available

Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community

NCT06289192
View directory record Official record
Conditions
Tobacco Dependence
Interventions
C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker, Lung Cancer Screening
Behavioral · Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
3
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Maine Lung Cancer Coalition: Using CHWs for the Annual Lung Cancer Screening Reminder

NCT04007458
View directory record Official record
Conditions
Lung Cancer
Interventions
Letter, Community Health Worker Phone Call
Behavioral
Lead sponsor
Anne Conners
Other
Eligibility
55 Years to 80 Years
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Augusta, Maine
Source: ClinicalTrials.gov public record
Updated Nov 29, 2020 · Synced Sep 27, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adaptation and Pilot Testing of a Lung Cancer Screening Decision Aid for Patients From a Safety-Net Healthcare System

NCT07382557
View directory record Official record
Conditions
Lung Cancer
Interventions
Surveys, Focus groups, Cognitive Interviews, Lung cancer screening decision aid video, Colon cancer screening video
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)

NCT03611881
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
Counseling, Nicotine patch, Community Resource
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
642 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
6
States / cities
Boston, Massachusetts • Newton, Massachusetts • Oak Bluffs, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Increasing Adherence to Lung Cancer Screening

NCT05832008
View directory record Official record
Conditions
Lung Cancer, Adherence, Patient
Interventions
Patient Nudge, Clinician Nudge
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 80 Years
Enrollment
825 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT03178552
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
Alectinib, Atezolizumab, Pemetrexed, Cisplatin, Carboplatin, Gemcitabine, Entrectinib, Cobimetinib, Vemurafenib, Bevacizumab, Divarasib, Docetaxel
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
12
States / cities
Sacramento, California • Denver, Colorado • Fort Myers, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Connected Health to Increase Lung Cancer Screening

NCT04612946
View directory record Official record
Conditions
Lung Cancer
Interventions
Referral to Telemedicine LCS Counseling Visit, Usual Care
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
55 Years to 77 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Sep 27, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

NCT06716580
View directory record Official record
Conditions
Lung Cancer, EGFR Gene Mutation
Interventions
Circulating Tumor DNA (ctDNA) Assay
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
40 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
6
States / cities
Boston, Massachusetts • Brighton, Massachusetts • Methuen, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Project PLUS Lung Cancer Screening Promotion

NCT05937399
View directory record Official record
Conditions
Lung Cancer
Interventions
Intervention video, Control video
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Sep 27, 2026, 2:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Eligibility Screening for the NIH Intramural Research Program Clinical Protocols

NCT00026754
View directory record Official record
Conditions
Breast Cancer, Prostate Cancer, Lung Cancer, Sarcoma, Melanoma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
1 Month and older
Enrollment
19,522 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 27, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Increasing Equity in Lung Cancer Screening

NCT06360822
View directory record Official record
Conditions
Lung Cancer
Interventions
ED-LCS
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
50 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer

NCT05384769
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Liquid Biopsy, Low Dose Computed Tomography of the Chest, Survey Administration
Procedure · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
50 Years to 80 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Pilot Study of High Risk Lung Cancer Screening

NCT03683940
View directory record Official record
Conditions
Lung Cancer
Interventions
Screening
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 82 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 27, 2026, 2:51 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

A Study to Develop a Strategy to Increase Lung Cancer Screening in Women Who May Be at Risk for Lung Cancer

NCT04848961
View directory record Official record
Conditions
Smoking
Interventions
LungTalk
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Active, not recruiting No phase listed Observational

Early Detection of Lung Cancer

NCT03181256
View directory record Official record
Conditions
Lung Cancer
Interventions
Biospecimen collection, Pulmonary Function Test, Computed Tomography (CT), Laboratory Biomarker
Procedure · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
55 Years to 80 Years
Enrollment
45 participants
Timeline
2017 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The INSPIRE-Lung Study

NCT05824273
View directory record Official record
Conditions
Lung Cancer
Interventions
LungTalk, Non-tailored intervention - Standard of practice
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
50 Years to 80 Years
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Nutley, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Fluorescent Light Bronchoscopy Plus White Light Bronchoscopy for Early Detection of Lung Cancer

NCT00019201
View directory record Official record
Conditions
Head and Neck Cancer, Lung Cancer
Interventions
cytology specimen collection procedure, immunohistochemistry staining method, sputum cytology, bronchoscopic and lung imaging studies, bronchoscopy, comparison of screening methods, endoscopic biopsy
Other · Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1996
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 27, 2026, 2:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement

NCT03891602
View directory record Official record
Conditions
Smoking, Smoking, Tobacco, Smoking, Cigarette, Lung Cancer
Interventions
Cataldo Lung Cancer Stigma Scale (Smoking-Related Subscale), Patient Trust in the Medical, Decision Conflict Scale (DCS) - Lung Cancer Screening, Shared Decision Making Questionnaire (SDM-Q)- Patient, Stage of Readiness for Smoking Cessation - Contemplation Ladder, Primary Care Clinicians' Lung Cancer Screening Survey
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 80 Years
Enrollment
654 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 27, 2026, 2:51 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Tailored Screening and Smoking Cessation Program for the LGBTQ Community of Seattle

NCT05304390
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Patient Navigation, Questionnaire Administration, Smoking Cessation Intervention, Carbon Monoxide Measurement
Behavioral · Other · Procedure
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 27, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital

NCT07146568
View directory record Official record
Conditions
Lung Cancer, Cancer of the Lung
Interventions
Pink and Pearl Campaign
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years and older
Enrollment
5,515 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 27, 2026, 2:51 PM EDT