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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Carbon Dioxide Insufflation Clear all
Completed Not applicable Interventional

A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP)

NCT00685386
View directory record Official record
Conditions
Cholestasis
Interventions
CO2 insufflation, Room air insufflation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Jul 23, 2026, 7:06 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Comparison Air Versus Carbon Dioxide Insufflation in Single Balloon Anterograde Enteroscopy

NCT03811522
View directory record Official record
Conditions
Carbon Dioxide Insufflation, Anterograde Single Balloon Enteroscopy
Interventions
carbon dioxide insufflation, Air insufflation
Other
Lead sponsor
North Eastern Ohio Gastroenterology and Endoscopy center
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Warren, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Impact of Carbon Dioxide Insufflation and Water Exchange on Post-Colonoscopy Outcomes

NCT02409979
View directory record Official record
Conditions
Abdominal Pain
Interventions
Carbon dioxide method, Water Exchange-CO2, Water Exchange-AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 80 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2015 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

AirSeal®Insufflation Trocar/CO2 Absorption Study

NCT02654808
View directory record Official record
Conditions
Gynecologic Diseases
Interventions
AirSeal trocar, Standard trocar
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional

A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy

NCT02619656
View directory record Official record
Conditions
Pneumoperitoneum
Interventions
CO2 insufflation, Ambient air insufflation
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jul 23, 2026, 7:06 PM EDT
Recruiting Not applicable Interventional

Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery

NCT05838300
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Warm humidified CO2, Dry CO2
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional

U-POEM vs CO2-POEM

NCT06918730
View directory record Official record
Conditions
Esophageal Motility Disorders
Interventions
U-POEM, CO2-POEM
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional Results available

Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant

NCT04541667
View directory record Official record
Conditions
Endoscopy
Interventions
Air, Carbon Dioxide
Other
Lead sponsor
University of Nebraska
Other
Eligibility
6 Months to 19 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon

NCT02117232
View directory record Official record
Conditions
Colonic Adenomatous Polyps
Interventions
Visualization balloon, Traditional CO2 insufflation colonoscopy
Device
Lead sponsor
Mercy Medical Center
Other
Eligibility
17 Years to 90 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Phase 4 Interventional Results available

Safety and Efficacy of CO2 for Endoscopy

NCT03287687
View directory record Official record
Conditions
Endoscopy, Insufflation
Interventions
Carbon dioxide (CO2) gas insufflation, Air insufflation
Drug
Lead sponsor
Warren Bishop
Other
Eligibility
6 Months to 21 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jul 23, 2026, 7:06 PM EDT
Recruiting Not applicable Interventional

Safety and Efficacy of Carbon Dioxide Gas for Endoscopy

NCT06134154
View directory record Official record
Conditions
Abdominal Pain
Interventions
Endoscopic insufflation gas
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
6 Months to 18 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Veress Entry With/Without Concomitant CO2

NCT02896036
View directory record Official record
Conditions
Laparoscopy, Laparoscopic Surgery, Insufflation, Gynecologic Surgical Procedures
Interventions
Veress needle entry with concomitant CO2, Veress needle entry with subsequent CO2
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Jul 23, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy

NCT01954862
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., CO2 insufflation, Water Immersion/CO2, Water Exchange/CO2, Water Immersion/AI, Water Exchange/AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
624 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Jul 23, 2026, 7:06 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

NCT01782014
View directory record Official record
Conditions
Screening Colonoscopy
Interventions
colonoscopy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2016 · Synced Jul 23, 2026, 7:06 PM EDT