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Showing 1–24 of 9,754 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiac Clear all
Completed Not applicable Interventional Results available

Outlook Quality of Life Intervention Study

NCT01044290
View directory record Official record
Conditions
Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD), End Stage Renal Disease (ESRD)
Interventions
Life Completion, Attention Control
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 95 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Esophageal Cooling in Radiofrequency Cardiac Ablation

NCT03481023
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
EnsoETM, Conventional Care
Device · Procedure
Lead sponsor
Riverside Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Kankakee, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jun 26, 2026, 4:32 AM EDT
Recruiting Not applicable Interventional

Cord Clamping Among Neonates With Congenital Heart Disease

NCT06153459
View directory record Official record
Conditions
Congenital Heart Disease (CHD)
Interventions
Umbilical Cord Clamping at ~30 seconds, Umbilical Cord Clamping at ~120 seconds, Umbilical Cord Milking
Procedure
Lead sponsor
Carl Backes, MD
Other
Eligibility
37 Weeks to 42 Weeks
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
18
States / cities
Birmingham, Alabama • Los Angeles, California • Orange, California + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Jun 26, 2026, 4:32 AM EDT
Recruiting Phase 2 Interventional

Repurposing Valsartan May Protect Against Pulmonary Hypertension

NCT06053580
View directory record Official record
Conditions
Pulmonary Arterial Hypertension, Right Heart Failure, Right Ventricular Dysfunction, Pulmonary Vascular Disorder
Interventions
Valsartan 40 mg, Placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 26, 2026, 4:32 AM EDT
Withdrawn Not applicable Interventional

Effect of Right Ventricular Lead Position on Defibrillation Threshold

NCT02844127
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation
Interventions
Implantable Cardioverter Defibrillator (ICD)
Procedure
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Phase 2 Interventional

Impact of a Psychological Biofeedback-Relaxation Intervention on Clinical, Physical and Psychological Outcomes in Patients With Heart Failure

NCT00255931
View directory record Official record
Conditions
Heart Failure
Interventions
Cognitive Behavioral Therapy, Attention Placebo
Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
21 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 4, 2012 · Synced Jun 26, 2026, 4:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Coronary Artery Disease and Its Association With Liver Steatosis Among HIV-Infected Persons

NCT00889577
View directory record Official record
Conditions
HIV Infections, Coronary Artery Disease, Non-Alcoholic Fatty Liver Disease
Interventions
Not listed
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline

NCT04682977
View directory record Official record
Conditions
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Interventions
IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Sprinter Legend Balloon Catheter

NCT00961311
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Percutaneous Coronary Intervention, Sprinter Legend 1.25mm Balloon Catheter
Procedure · Device
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2011 · Synced Jun 26, 2026, 4:32 AM EDT
Active, not recruiting Not applicable Interventional

Improving Patient and Family Health Using Family-Centered Outcomes and Shared Decision-Making

NCT04437069
View directory record Official record
Conditions
Patient Decision Aids, Congenital Heart Disease, Congenital Heart Defect
Interventions
Decision Aid, Values Clarification Exercise
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Phase 2 Interventional Results available

A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function

NCT03357731
View directory record Official record
Conditions
Heart Failure, Cardiac Failure, Reduced Ventricular Ejection Fraction
Interventions
HNO Donor, Nitroglycerin (NTG), Placebo
Drug · Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
6
States / cities
Tustin, California • Chicago, Illinois • Indianapolis, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Jun 26, 2026, 4:32 AM EDT
Completed No phase listed Observational

Frequency Analysis of Coronary Artery Disease

NCT01043237
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 89 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 4, 2014 · Synced Jun 26, 2026, 4:32 AM EDT
Terminated No phase listed Observational

Retrospective Evaluation of Carvedilol Versus Captopril in CHF Patients

NCT00249067
View directory record Official record
Conditions
Heart Failure, Heart Murmurs
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2007 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional

High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy

NCT03335332
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
High intensity exercise, Moderate intensity exercise
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Phase 3 Interventional Results available

Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients With Cardiovascular Disease

NCT00071032
View directory record Official record
Conditions
Anemia, Hematologic Diseases, Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Thromboembolism, Pneumonia, Cerebrovascular Accident
Interventions
Liberal (10 g/dL) Transfusion Strategy, Restrictive (Symptomatic) Transfusion Strategy
Biological
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years and older
Enrollment
2,016 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 15, 2020 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Phase 1 Interventional Results available

Subcutaneous Furosemide in Acute Decompensated Heart Failure Pilot

NCT02877095
View directory record Official record
Conditions
Acute Heart Failure
Interventions
Furosemide
Drug
Lead sponsor
Adrian Hernandez
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
5
States / cities
Atlanta, Georgia • Boston, Massachusetts • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Jun 26, 2026, 4:32 AM EDT
Completed No phase listed Observational

Novel Imaging Biomarkers for Mechanical Complications in Acute Myocardial Infarction

NCT06450912
View directory record Official record
Conditions
Acute Myocardial Infarction, Hemorrhagic Myocardial Infarction, Myocardial Stunning, Myocardial Hemorrhage, Myocardial Reperfusion Injury, Myocardial Rupture (Post Infarct)
Interventions
Not listed
Lead sponsor
Rohan Dharmakumar
Other
Eligibility
18 Years to 79 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Jun 26, 2026, 4:32 AM EDT
Recruiting No phase listed Observational

Pediatric Cardiomyopathy Mutation Analysis

NCT02432092
View directory record Official record
Conditions
Cardiomyopathies, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Restrictive Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy, Left Ventricular Non-compaction Cardiomyopathy
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jun 26, 2026, 4:32 AM EDT
Not yet recruiting No phase listed Observational

Vascular Endothelial Inflammation and Health Status In INOCA (VISION-INOCA)

NCT07586241
View directory record Official record
Conditions
Ischemia and Non-obstructive Coronary Arteries
Interventions
Invasive coronary angiography, Coronary Artery Endothelial Cell Sampling, Fitbit, Invasive coronary function testing
Procedure · Device · Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Vagus Nerve Stimulation to Suppress Atrial Fibrillation

NCT02548754
View directory record Official record
Conditions
Atrial Fibrillation, Inflammation
Interventions
Parasym device
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

ASSURE WCD Clinical Evaluation - Conversion Efficacy Study

NCT04132466
View directory record Official record
Conditions
Death, Sudden, Cardiac
Interventions
Defibrillation using the ASSURE wearable cardioverter defibrillator therapy delivered via a waveform delivery test system
Device
Lead sponsor
Kestra Medical Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Anchorage, Alaska • Ann Arbor, Michigan • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jun 26, 2026, 4:32 AM EDT
Completed Not applicable Interventional

Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.

NCT07361731
View directory record Official record
Conditions
Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques, Opioid Craving, Recovery, Emotional Regulation, Positive and Negative Affect, Stress, Biofeedback
Interventions
Heart rate variability biofeedback
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 26, 2026, 4:32 AM EDT
Terminated Not applicable Interventional

Efficacy Rate of Unipolar Polarity Switch for Lesion Assessment in Pulmonary Vein Isolation

NCT05464537
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Unipolar Polarity Switch Left, Unipolar Polarity Switch Right
Other
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Jun 26, 2026, 4:32 AM EDT
Terminated No phase listed Observational

SPIROCOR Coronary Outcome by Respiratory Stress Examination

NCT01053975
View directory record Official record
Conditions
Severe Coronary Artery Disease (S-CAD)
Interventions
Not listed
Lead sponsor
Spirocor
Industry
Eligibility
30 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
29
States / cities
Birmingham, Alabama • Huntsville, Alabama • Glendale, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2010 · Synced Jun 26, 2026, 4:32 AM EDT