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Showing 1–24 of 162 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiac Pacing Clear all
Completed Not applicable Interventional

Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection Fraction

NCT04721314
View directory record Official record
Conditions
Pacemaker, Diastolic Dysfunction, Diastolic Heart Failure
Interventions
Adjustment of lower rate limit, Maintenance of lower rate limit
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Sep 8, 2026, 2:02 AM EDT
Terminated Phase 4 Interventional Results available

Right Ventricular (RV) Pacing in Early Post-operative Continuous Flow Left Ventricular Assist Device (LVAD)

NCT01446796
View directory record Official record
Conditions
Heart Failure
Interventions
Implantable Cardioverter-Defibrillator (subject's pre-existing ICD)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Sep 8, 2026, 2:02 AM EDT
Not listed Not applicable Interventional

Physiologic Pacing for Symptomatic First-Degree Heart Block

NCT06245304
View directory record Official record
Conditions
Symptomatic First-degree Heart Block
Interventions
Dual chamber Medtronic pacemaker implantation., DDD-50 pacing program, AAI-DDD 50 pacing program
Device · Other
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 8, 2026, 2:02 AM EDT
Completed No phase listed Observational Results available

Physiologic Pacing Registry

NCT03719040
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction, Heart Block, Syncope, Cardiomyopathies, Ventricular Tachycardia, Heart Failure
Interventions
Physiologic pacing device implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
870 participants
Timeline
2018 – 2021
U.S. locations
26
States / cities
Huntsville, Alabama • Burlingame, California • San Diego, California + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Not applicable Interventional Results available

Micra Transcatheter Pacing System Continued Access Study Protocol

NCT02488681
View directory record Official record
Conditions
Bradycardia
Interventions
Micra Pacemaker Implant
Device
Lead sponsor
Medtronic
Industry
Eligibility
18 Years and older
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
29
States / cities
Los Angeles, California • New Haven, Connecticut • Jacksonville, Florida + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2018 · Synced Sep 8, 2026, 2:02 AM EDT
Completed No phase listed Observational

ELEVATE (Evaluation of Left Ventricular Autothreshold) 3.0

NCT01539629
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac pacing
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
4
States / cities
Davenport, Iowa • Yardley, Pennsylvania • Richmond, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Sep 8, 2026, 2:02 AM EDT
Completed No phase listed Observational

Evaluation of Left Ventricular Autothreshold, Phase Two

NCT01242722
View directory record Official record
Conditions
Heart Failure
Interventions
CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Stuebenville, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)

NCT06601322
View directory record Official record
Conditions
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Interventions
Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 8, 2026, 2:02 AM EDT
Terminated Not applicable Interventional Results available

Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate

NCT00698139
View directory record Official record
Conditions
Heart Failure
Interventions
Medtronic Pacemaker
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 90 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Sep 8, 2026, 2:02 AM EDT
Completed No phase listed Observational Results available

ProMRI Study of the Entovis Pacemaker System (Phase B)

NCT02009696
View directory record Official record
Conditions
Magnetic Resonance Imaging (MRI); Cardiac Pacing
Interventions
Patients with a ProMRI Pacemaker System, Magnetic Resonance Imaging (MRI) scan
Device · Other
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
32
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Concord, California + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Physiologic Accelerated Pacing as a Treatment in Patients With Heart Failure With Preserved Ejection Fraction

NCT04546555
View directory record Official record
Conditions
Heart Failure, Diastolic
Interventions
Dual chamber pacemaker, Accelerated Physiologic Pacing, Nocturnal Pacing
Device · Other
Lead sponsor
Daniel L Lustgarten
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Sep 8, 2026, 2:02 AM EDT
Completed No phase listed Observational

Parallel Mapping for Ventricular Tachycardia

NCT04477499
View directory record Official record
Conditions
Ventricular Tachycardia (V-Tach), Implantable Cardioverter Defibrillator (ICD), Arrythmia
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Not applicable Interventional Results available

Model 4396 Left Ventricular (LV) Lead Study

NCT00853593
View directory record Official record
Conditions
Heart Failure
Interventions
Pacing Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
19
States / cities
Pasadena, California • Sacramento, California • Atlantis, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2019 · Synced Sep 8, 2026, 2:02 AM EDT
Recruiting No phase listed Observational

Single Chamber Atrial Leadless Pacing for Isolated Sinus Node Dysfunction

NCT07638995
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Implantable Loop Recorder
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Bay Shore, New York • Huntington, New York • Manhasset, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 8, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Elevated Rate Pacing of Cardiac Amyloidosis

NCT07583823
View directory record Official record
Conditions
Cardiac Amyloidosis, Pacemaker
Interventions
Pacemaker Rate
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 8, 2026, 2:02 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable

NCT06763549
View directory record Official record
Conditions
Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure, HFrEF - Heart Failure with Reduced Ejection Fraction, HFpEF - Heart Failure with Preserved Ejection Fraction, Syncopation, Syncope, Ischemic Cardiovascular Disease, STEMI, STEMI (ST Elevation MI), Atrial Fibrillation (AF), Atrial Enlargement, LVF, Conduction Defect, Conduction Abnormalities, Heart Block, Valvular Diseases, Cardiac Output, Low, Stroke Volume, Stroke Volume Variation, Hyperkalemia, Hypercalcemia, Hypocalcemia, LV Dysfunction, QT Prolongation, Sudden Cardiac Death Due to Cardiac Arrhythmia, Ventricular Arrhythmia, Pacing, Pacing Induced Dyssynchrony, Silent Ischemia, Pericarditis, Sleep Related Breathing Disorder, RSA, Apnea, Obstructive, Cardiac Output Measurement, Respiratory Impedance, CRT And/or ICD, Infarction, Cardiomyopathies, Primary, Hypertrophy
Interventions
SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C, SUBPROTOCOL D, SUBPROTOCOL E, SUBPROTOCOL F, SUBPROTOCOL G, SUBPROTOCOL H
Device
Lead sponsor
Peerbridge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
15,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 8, 2026, 2:02 AM EDT
Completed No phase listed Observational

Micra AV Transcatheter Pacing System Post-Approval Registry

NCT04253184
View directory record Official record
Conditions
Bradycardia
Interventions
Micra AV Transcatheter Pacing System
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
46
States / cities
Birmingham, Alabama • Rancho Mirage, California • Redwood City, California + 37 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 8, 2026, 2:02 AM EDT
Active, not recruiting Not applicable Interventional

Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE)

NCT05541679
View directory record Official record
Conditions
Complete Heart Block, High Degree Second Degree Atrioventricular Block, Pacemaker-Induced Cardiomyopathy, Aortic Valve Stenosis
Interventions
Right ventricular septal pacing followed by left bundle branch area pacing, Left bundle branch area pacing followed by right ventricular septal pacing
Device
Lead sponsor
Main Line Health
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
Overland Park, Kansas • Ridgewood, New Jersey • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Phase 4 Interventional

Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications

NCT00560768
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Ovatio VR 6250 or DR6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
Not listed
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
7
States / cities
Sheffield, Alabama • Tarzana, California • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Phase 2Phase 3 Interventional

Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation

NCT00387803
View directory record Official record
Conditions
Heart Failure, Congestive, Ventricular Fibrillation, Tachycardia, Ventricular
Interventions
Cardiac Resynchronization Therapy with Defibrillation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
581 participants
Timeline
1998 – 2001
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 24, 2007 · Synced Sep 8, 2026, 2:02 AM EDT
Completed Phase 4 Interventional

Syncope: Pacing or Recording in the Later Years

NCT01423994
View directory record Official record
Conditions
Syncope, Heart Block, Conduction Disorder of the Heart
Interventions
pacemaker, implantable loop recorder
Procedure
Lead sponsor
Canadian Institutes of Health Research (CIHR)
Government
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Sep 8, 2026, 2:02 AM EDT
Terminated Not applicable Interventional Results available

Optimize RV Selective Site Pacing Clinical Trial

NCT00422669
View directory record Official record
Conditions
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Interventions
Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
16
States / cities
Bridgeport, Connecticut • Clearwater, Florida • Hudson, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Sep 8, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

AI-Guided Left Bundle Branch Area Pacing

NCT07206602
View directory record Official record
Conditions
Heart Failure
Interventions
AI-assisted Left Bundle Branch Area Pacing, Left Bundle Branch Area Pacing
Device · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 8, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Chronic Evaluation of Novel Pacemaker System

NCT06056817
View directory record Official record
Conditions
Ventricular Pacing With Rate Response, Bradycardia
Interventions
Calyan Pacemaker
Device
Lead sponsor
Calyan Technologies
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 8, 2026, 2:02 AM EDT