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ClinicalTrials.gov public records Last synced Sep 22, 2026, 5:49 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiac Patients Clear all
Recruiting No phase listed Observational

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

NCT05014802
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
Interventions
Not listed
Lead sponsor
Tulane University
Other
Eligibility
40 Years to 120 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Covington, Louisiana • New Orleans, Louisiana • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Not applicable Interventional

A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs)

NCT02026102
View directory record Official record
Conditions
Systolic Heart Failure, Sudden Cardiac Death
Interventions
ICD Decision Aid Toolkit
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Sep 22, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

Intraoperative Music Therapy in TAVR Patients

NCT07591922
View directory record Official record
Conditions
Anxiety
Interventions
Music, Control Group (no music)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 22, 2026, 5:49 PM EDT
Not listed Not applicable Interventional

Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks

NCT03577002
View directory record Official record
Conditions
Congestive Heart Failure, Cancer, Chronic Obstructive Pulmonary Disease, Cerebrovascular Accident, Frail Elderly Syndrome, Cardiovascular Diseases
Interventions
Serious Illness Care Program (SICP)
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
1,120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Aurora, Colorado • Iowa City, Iowa • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Sep 22, 2026, 5:49 PM EDT
Enrolling by invitation Not applicable Interventional

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)

NCT06052072
View directory record Official record
Conditions
Group 2 Pulmonary Hypertension, Heart Failure
Interventions
Gradient Denervation System
Device
Lead sponsor
Gradient Denervation Technologies
Industry
Eligibility
22 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
8
States / cities
Chicago, Illinois • Boston, Massachusetts • Durham, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 22, 2026, 5:49 PM EDT
Active, not recruiting Phase 3 Interventional

Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

NCT04083339
View directory record Official record
Conditions
Diabetic Cardiomyopathies
Interventions
AT-001, Placebo
Drug
Lead sponsor
Applied Therapeutics, Inc.
Industry
Eligibility
40 Years and older
Enrollment
675 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
28
States / cities
Beverly Hills, California • La Jolla, California • Lincoln, California + 20 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 22, 2026, 5:49 PM EDT
Completed No phase listed Observational

FORE-SIGHT Tissue Oximeter During Cardiac Surgery

NCT02426268
View directory record Official record
Conditions
Cardiac Surgical Patients
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 22, 2026, 5:49 PM EDT
Recruiting Phase 4 Interventional

Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score

NCT07490067
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogenomics (PGx)
Drug · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients

NCT02739464
View directory record Official record
Conditions
Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
Interventions
Exercise + SOC PT/OT, SOC PT/OT
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
7 Years to 60 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
4
States / cities
Davis, California • Dallas, Texas • Galveston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Phase 4 Interventional Results available

Personalized Treatments for Depressive Symptoms in Patients With Advanced Heart Failure

NCT03688100
View directory record Official record
Conditions
Depression, Heart Failure
Interventions
Behavioral Activation Therapy, Medication Management
Behavioral · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 22, 2026, 5:49 PM EDT
Terminated No phase listed Observational

Comparison of Different Locations for Pulse Oximetry Probes in Cardiovascular (CV) Patients With Poor Peripheral Perfusion

NCT01128036
View directory record Official record
Conditions
Congestive Heart Failure, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 8, 2011 · Synced Sep 22, 2026, 5:49 PM EDT
Terminated No phase listed Observational

A Prospective Study With a New Device for the Monitoring of Cerebral Oxygenation on Cardiac Surgery Patients

NCT00598936
View directory record Official record
Conditions
Coronary Artery Disease, Heart Valve Disease
Interventions
CDI 1000 COM and INVOS 5100
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2011 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Phase 1Phase 2 Interventional

Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure

NCT01187836
View directory record Official record
Conditions
Heart Failure
Interventions
TRV120027, Placebo
Drug
Lead sponsor
Trevena Inc.
Industry
Eligibility
18 Years to 79 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Miami, Florida • Baltimore, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 22, 2026, 5:49 PM EDT
Not yet recruiting Not applicable Interventional

Light Utilization COX-Inhibitory Device Therapy for Infant Cardiac Arrest (LUTICA Study). The LUCID Device is Used in the Treatment of Ischemic Brain Reperfusion Injury Caused by Cardiac Arrest in Pediatric Patients.

NCT07556939
View directory record Official record
Conditions
Reperfusion Injury, Post Cardiac Arrest Brain Injury
Interventions
LUTICIA - Light Utilization COX-Inhibitory Device)
Device
Lead sponsor
Mitovation, Inc
Industry
Eligibility
48 Hours to 1 Year
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

The Cascade Feasibility Pilot (HF) Phase 3

NCT04993287
View directory record Official record
Conditions
Heart Failure
Interventions
Non-invasive continuous remote monitoring with structured escalation pathway, Affective Analysis of Participant Response to Continuous Remote Patient Monitoring
Other
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Phase 3 Interventional

Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management

NCT01584557
View directory record Official record
Conditions
Heart Failure
Interventions
Tolvaptan or Samsca, placebo or sugar pill
Drug
Lead sponsor
Cardiovascular Clinical Sciences Inc
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
37
States / cities
Birmingham, Alabama • Huntsville, Alabama • Los Angeles, California + 34 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Phase 4 Interventional

Pharmacodynamic Study of Carvedilol Versus Metoprolol in Heart Failure

NCT00802230
View directory record Official record
Conditions
Heart Failure
Interventions
Terbutaline Infusion
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Sep 22, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients

NCT02922036
View directory record Official record
Conditions
Heart Failure
Interventions
WiSE System
Device
Lead sponsor
EBR Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
43
States / cities
Huntsville, Alabama • La Jolla, California • Fort Lauderdale, Florida + 37 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT

NCT04799899
View directory record Official record
Conditions
Cardiovascular Diseases, Acute Coronary Syndrome, Depression
Interventions
Adapted MBCT, Cardiac Health Enhancement
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
35 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 22, 2026, 5:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Accuracy of an Artificially-intelligent Stethoscope

NCT00564122
View directory record Official record
Conditions
Heart Murmurs, Congenital Heart Disease, Structural Heart Disease
Interventions
Artificially-Intelligent Stethoscope, Physical Examination
Device · Other
Lead sponsor
Akron Children's Hospital
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
3
States / cities
Akron, Ohio • Beachwood, Ohio • Boardman, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 31, 2011 · Synced Sep 22, 2026, 5:49 PM EDT
Completed Phase 1 Interventional

Study to Evaluate TRV120027 on Renal Pharmacodynamics in Patients With Heart Failure and Renal Dysfunction

NCT01444872
View directory record Official record
Conditions
Heart Failure, Kidney Disease
Interventions
TRV120027, Normal Saline
Drug
Lead sponsor
Trevena Inc.
Industry
Eligibility
18 Years to 74 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
4
States / cities
Orlando, Florida • Minneapolis, Minnesota • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2012 · Synced Sep 22, 2026, 5:49 PM EDT
Completed No phase listed Observational

Implantable Cardiac Defibrillators for the Prevention of Sudden Death in Patients With Cardiac Sarcoidosis

NCT01013311
View directory record Official record
Conditions
Sarcoidosis of the Heart, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 22, 2026, 5:49 PM EDT
Completed No phase listed Observational

Reversal of Obese/Diabetic Cardiomyopathy After Gastric Bypass Surgery

NCT01067209
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 22, 2026, 5:49 PM EDT