Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 6, 2026, 2:06 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 1,408 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cardiovascular Function Clear all

Conditions: Cardiovascular Diseases
Interventions: Estradiol+MPA, Estradiol+Drospirenone; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 45 Years to 75 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Atherosclerosis
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 579 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Postural Tachycardia Syndrome
Interventions: Placebo, Modafinil, Propranolol; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hyperglycemia, Aortic Valve Replacement, Aortic Stenosis, Cardiac Surgery
Interventions: hyperinsulinemic normoglycemic clamp (HNC), control group; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 40 Years to 84 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Diastolic Heart Failure, Heart Failure With Preserved Ejection Fraction
Interventions: Functional circuit training and lifestyle counseling, Health education and independent walking; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 60 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Gingivitis, Cardiovascular Diseases, Gingival Diseases, Gingival Bleeding, Periodontal Diseases
Interventions: dietary nitrate, Placebo chewing gum; Dietary Supplement · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Functional Disability, Dementia, Heart Disease, Stroke, Cancer, Bleeding, Depression
Interventions: 100 mg enteric-coated aspirin, Placebo; Drug
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 65 Years and older
Enrollment: 19,114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2024
U.S. locations: 33
States / cities: Birmingham, Alabama • Palo Alto, California • Washington D.C., District of Columbia + 26 more

Conditions: Mitral Valve Insufficiency, Mitral Valve Regurgitation, Mitral Valve Incompetence, Mitral Regurgitation, Mitral Insufficiency
Interventions: Percutaneous mitral valve repair using MitraClip implant; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 2
States / cities: Evanston, Illinois • Indianapolis, Indiana

Conditions: Congenital Disorders
Interventions: Not listed
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: Up to 21 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1990 – 2008
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Amyloidosis, Paraproteinemias, Cardiomyopathies
Interventions: Amyloidosis, Cardiac Amyloidosis; Other
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
Interventions: Ralinepag; Drug
Lead sponsor: United Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 48
States / cities: Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 38 more

Conditions: HIV Infection, Pulmonary Hypertension, Endothelial Function, HIV Infections
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 365 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Stroke
Interventions: Not listed
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Heart Failure, Diastolic Heart Failure, Heart Failure With Normal Ejection Fraction
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Stroke
Interventions: Stroke Rehabilitation; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2003
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: MPS I, MPS IV A, MPS - Mucopolysaccharidosis, MPS IVA
Interventions: Not listed
Lead sponsor: Children's Hospital of Orange County; Other
Eligibility: 0 Years to 99 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2030
U.S. locations: 3
States / cities: Orange, California • Minneapolis, Minnesota • St Louis, Missouri

Conditions: Cardiovascular Health, Cardiovascular Risk Factor
Interventions: Potassium chloride supplement, Placebo; Dietary Supplement
Lead sponsor: University of Delaware; Other
Eligibility: 18 Years to 45 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Cardiovascular Disease, Hematologic Diseases, Immunologic Disease, Cancer, Respiratory Function
Interventions: Not listed
Lead sponsor: National Institute of Environmental Health Sciences (NIEHS); NIH
Eligibility: 21 Years and older
Enrollment: 32,658 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphoid, Acute, Cardiotoxicity
Interventions: observation only; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years to 90 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Type 2 Diabetes, Cardiovascular Diseases
Interventions: Egg included vegan phase, Vegan Phase; Other
Lead sponsor: Griffin Hospital; Other
Eligibility: 25 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Derby, Connecticut

Conditions: High Blood Pressure, Liver Transplant, Renal Function Abnormal
Interventions: Amlodipine Besylate, Chlorthalidone; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Hypertension
Interventions: Isosorbide Mononitrate, sustained release, Placebo capsule; Drug
Lead sponsor: Corporal Michael J. Crescenz VA Medical Center; Federal
Eligibility: 18 Years to 89 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Kidney Disease, Hypertension
Interventions: Procedure: Regional phenylephrine arterial infusion; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Cardiovascular Disease
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

Effect of Estradiol+Drospirenone Versus Estradiol+MPA on Endothelial Function

Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection

Modafinil and Cognitive Function in POTS

The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose

Role of Exercise in Diastolic Heart Failure

Dietary Nitrate Functional Gum Effect on Gingivitis and Heart Health

Aspirin in Reducing Events in the Elderly

EVEREST II Pivotal Study High Risk Registry (HRR)

Racial Distribution of Heterotaxy Syndrome

Prospective Identification of Cardiac Amyloidosis by Cardiac Magnetic Resonance Imaging

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension

Assessment of the Stroke Rehabilitation Assessment of Movement as a Clinical Tool

Left Ventricular Torsional Hysteresis: A Global Parameter for Diastolic Function

Video-Based Functional Performance and Assessment Following Stroke

Cardiac Structure and Function in MPS

The Potassium Supplementation Study

Gulf Long-Term Follow-Up Study

Cardiovascular Function in Acute Leukemia

The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

Effect of Isosorbide Mononitrate on Hypertension to Improve Left Ventricular Hypertrophy, Fibrosis and Myocardial Function

Alpha-Adrenoceptor Vascular Function In Chronic Kidney Disease Focus On The Role Of Endothelial Nitric Oxide

The Role of Nitric Oxide Synthase in Circulating Progenitor Cell Function