Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 1,408 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cardiovascular Function Clear all

Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
Interventions: Tendyne Mitral Valve System, MitraClip System; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 73
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 60 more

Conditions: Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
Interventions: Goode Health Beverage, Vanilla Base Beverage Blend; Dietary Supplement
Lead sponsor: The University of Texas at Arlington; Other
Eligibility: 18 Years to 55 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Arlington, Texas

Conditions: Stroke, Stroke, Acute, Stroke, Ischemic
Interventions: Frequent PT, Intense PT; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 80 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Coronary Artery Disease
Interventions: Vessel Fractional Flow Reserve; Diagnostic Test
Lead sponsor: Erasmus Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Single-ventricle, Congenital Heart Disease
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Failure, Ischemic Cardiomyopathy
Interventions: Not listed
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Diastolic Heart Failure
Interventions: Eplerenone; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
Interventions: Sotagliflozin, Placebo; Drug
Lead sponsor: Alessandro Doria; Other
Eligibility: 18 Years to 75 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 13
States / cities: Stanford, California • Aurora, Colorado • Orlando, Florida + 10 more

Conditions: Hypertension
Interventions: Concord Grape Juice; Dietary Supplement
Lead sponsor: Boston University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Single-ventricle
Interventions: Spironolactone; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 1 Year to 6 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Heart Disease
Interventions: noninvasive tests; Procedure
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 634 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2040
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Heart Failure, Mitral Valve Insufficiency, Cardiomyopathies
Interventions: Mitral valve repair; Device
Lead sponsor: Ancora Heart, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2024
U.S. locations: 16
States / cities: Atlanta, Georgia • Louisville, Kentucky • Minneapolis, Minnesota + 12 more

Conditions: Hypertension
Interventions: Melatonin, Placebo; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Turner Syndrome
Interventions: estrogen, androgen, placebo; Drug · Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 10 Years to 14 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1992 – 2012
U.S. locations: 2
States / cities: Bethesda, Maryland • Philadelphia, Pennsylvania

Conditions: Type 2 Diabetes, Cardiovascular Diseases
Interventions: prolonged SB, SB broken 1, SB broken 2; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 60 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Heart Failure, Reduced Ejection Fraction
Interventions: sacubitril/valsartan (LCZ696), enalapril, matching placebo sacubitril/valsartan (LCZ696), matching placebo enalapril; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 23
States / cities: Fort Payne, Alabama • Beverly Hills, California • Stockton, California + 20 more

Conditions: Multiple Myeloma
Interventions: Belantamab mafodotin; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 8
States / cities: Tucson, Arizona • Beverly Hills, California • Plantation, Florida + 5 more

Conditions: Congestive Heart Failure, Left Ventricular Failure, Atrial Fibrillation
Interventions: Catheter Ablation, FDA approved anti arrhythmic drug; Device · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 6
States / cities: Hartford, Connecticut • Akron, Ohio • Cleveland, Ohio + 3 more

Conditions: Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Cognition, Microvascular Function, Gut Microbiota, Endothelial Function (Reactive Hyperemia), Arterial Stiffness, Blood Pressure, Adult
Interventions: Peanuts; Dietary Supplement
Lead sponsor: Georgia State University; Other
Eligibility: 20 Years to 59 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Stroke, Aphasia
Interventions: Cortico-cortical paired associative stimulation, Sham cortico-cortical paired associative stimulation; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Hypercholesterolemia, Hypertension
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Endothelial Dysfunction, Vascular Stiffness, Left Ventricular Hypertrophy, Left Ventricular Dysfunction
Interventions: Sodium Reduction Intervention; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 40 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Rheumatoid Arthritis, Cardiovascular Diseases
Interventions: celecoxib 200mg capsule, naproxen sodium 550mg tablet, Aspirin 81mg tablet; Drug
Lead sponsor: Platelet and Thrombosis Research, LLC; Other
Eligibility: 18 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Aging
Interventions: Caloric Restriction (CR), Control; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 21 Years to 50 Years
Enrollment: 238 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 3
States / cities: Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri

Search by objective public record fields.

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

The Impact of Goode Health Beverage on Markers of Physiological and Neurocognitive Health

Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke

Fast Assessment of STenosis Severity- FASTII Study

Fontan Imaging Biomarkers (FIB) Study

Optima Coronary Artery Disease (CAD) (Optimal Mechanical Evaluation)

Reversing Endothelial and Diastolic Dysfunction and Improving Collagen Turnover in Diastolic Heart Failure

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Blood Pressure Lowering Effects of Grape Juice

Fibrosis and the Fontan

Heart Disease of the Small Arteries in Women and Men

The CorCinch - Functional Mitral Valve Regurgitation (FMR) Study

Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study

The Effect of Androgen and Growth Hormone on Height and Learning in Girls With Turner Syndrome

Sex Differences in the effecTs of brEaking uP Sedentary Behavior on vascUlar Function in Type 2 Diabetes

Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.

A Study of Belantamab Mafodotin in Multiple Myeloma Participants With Normal and Impaired Hepatic Function

Catheter Ablation vs. Medical Therapy in Congested Hearts With AF

Peanuts for Cardiometabolic, Brain, and Intestinal Health

Studying Language With Brain Stimulation in Aphasia

Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High Cholesterol

Sodium Lowering Vascular Effects Trial

NSAIDs vs. Coxibs in the Presence of Aspirin

CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy