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ClinicalTrials.gov public records Last synced Sep 4, 2026, 11:53 AM EDT

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Showing 1–24 of 461 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Cardiovascular Risk Factors Clear all
Completed No phase listed Observational Accepts healthy volunteers Results available

Risk Factors, Costs, and Impacts of ED Boarding

NCT07532564
View directory record Official record
Conditions
Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease), Sepsis, Hypertension, Heart Failure, Pneumonia, Urinary Tract Infection (Diagnosis), Chest Pain, Psychiatric Disorder, Sickle Cell Disease (SCD)
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
30,486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 4, 2026, 11:53 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Role of Cardiometabolic Risk Factors in Childhood Bone Development

NCT02355717
View directory record Official record
Conditions
Obesity, Cardiovascular Disease, Type 2 Diabetes, Osteoporosis
Interventions
Observational Study
Other
Lead sponsor
Augusta University
Other
Eligibility
9 Years to 15 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Sep 4, 2026, 11:53 AM EDT
Not listed Not applicable Interventional

Primary Prevention of Cardiovascular Disease Among Female Hospital Employees: The Heart Smart for Women Intervention

NCT04166097
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Heart Smart Interventional Program
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 4, 2026, 11:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans

NCT04101188
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Moderate Potassium/Low Sodium Diet, Moderate Potassium/High Sodium Diet, High Potassium/High Sodium Diet
Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Phase 4 Interventional Results available

A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors

NCT02019264
View directory record Official record
Conditions
Cardiovascular Disease, High Cardiovascular Risk, Obesity, Overweight, Type 2 Diabetes
Interventions
Lorcaserin hydrochloride, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
40 Years and older
Enrollment
14,673 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
373
States / cities
Alexander City, Alabama • Athens, Alabama • Birmingham, Alabama + 283 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional

Initial Test of the Time to Talk CARDIO (Creating a Real Dialogue In the Office) Program

NCT00983333
View directory record Official record
Conditions
Cardiovascular Disease, Cardiovascular Risk Factors
Interventions
Time to Talk CARDIO website
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
55 Years to 70 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2015 · Synced Sep 4, 2026, 11:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Cranberry Juice on Risk Factors for Cardiovascular Disease

NCT00631306
View directory record Official record
Conditions
Atherosclerosis
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 11, 2011 · Synced Sep 4, 2026, 11:53 AM EDT
Withdrawn Phase 2 Interventional

Effects of Nitric Oxide on the Endothelium During Hemolysis.

NCT03748082
View directory record Official record
Conditions
Endothelial Dysfunction, Hemolysis Intravascular, Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions
Nitric Oxide, Reactive Hyperemia Index, Endothelial Cells Collection
Drug · Diagnostic Test · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective, Single-Center, Non-Randomized Study of the PhysioWave™ Cardiovascular Analyzer

NCT03126994
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
PhysioWave Cardiovascular Analyzer, AtCor XCEL PWA & PWV, Detecto SOLO
Device
Lead sponsor
PhysioWave, Inc.
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 4, 2026, 11:53 AM EDT
Recruiting No phase listed Observational

Imaging the Pathogenesis of Cerebral Small Vessel Disease

NCT05703386
View directory record Official record
Conditions
Ischemic Stroke, Hypertension, Hyperlipidemias, Diabetes
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 4, 2026, 11:53 AM EDT
Completed No phase listed Observational

Genomic Determinants and Shared Genetic Pathways of Periodontal Disease

NCT03437798
View directory record Official record
Conditions
Periodontal Diseases, Diabetes, Osteoporosis, Cardiovascular Risk Factor
Interventions
Disease status
Other
Lead sponsor
Tufts University
Other
Eligibility
45 Years to 100 Years · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Sep 4, 2026, 11:53 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Genetic and Environmental Risk Factors for Hemorrhagic Stroke-GERFHS III

NCT00930280
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
1,260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Testosterone Replacement in Older Men and Atherosclerosis Progression

NCT00287586
View directory record Official record
Conditions
Hypogonadism, Atherosclerosis
Interventions
Testosterone Gel (Androgel), Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
60 Years and older · Male only
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
3
States / cities
Phoenix, Arizona • Los Angeles, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Sep 4, 2026, 11:53 AM EDT
Active, not recruiting Not applicable Interventional

A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients

NCT03127631
View directory record Official record
Conditions
Prostate Cancer, Cardiovascular Disease
Interventions
Nutrition, Exercise, Smoking cessation, Statin (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin), ACE inhibitor
Behavioral · Drug
Lead sponsor
McMaster University
Other
Eligibility
45 Years and older · Male only
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
4
States / cities
Augusta, Georgia • Kansas City, Kansas • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 4, 2026, 11:53 AM EDT
Completed No phase listed Observational

Evaluating Electrocardiogram (ECG) Abnormalities From Young Adulthood Through Middle Age

NCT00556751
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
5,115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1985 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Cherry Consumption in Reducing Risk Factors for Chronic Inflammatory Diseases

NCT01734070
View directory record Official record
Conditions
Inflammation, Cardiovascular Diseases
Interventions
Cherry consumption
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
45 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2013 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Carbohydrate Modification in Weight Management Among Obese Children

NCT00215111
View directory record Official record
Conditions
Childhood Obesity
Interventions
Low carbohydrate, reduced glycemic load, and a control diet
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 12 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Sep 4, 2026, 11:53 AM EDT
Completed No phase listed Observational

Cardiomyopathy Following Stem Cell Transplantation

NCT00352209
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional

Effects of Soy Based Dietary Supplements on Cardiometabolic Risk Factors.

NCT02490683
View directory record Official record
Conditions
Obesity, Cardiovascular Risk Factors
Interventions
Luna Rich X, Placebo, Reliv Now
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
35 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 4, 2026, 11:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Melatonin and Salt on Blood Vessel Function

NCT04325191
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Melatonin, Placebo
Dietary Supplement · Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating an Exercise Program to Reduce Cardiovascular Risk Factors in Children Infected With HIV

NCT00908284
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome, Cardiovascular Diseases
Interventions
Exercise Program, Control Group
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
2 Weeks to 25 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 6, 2015 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Cashew Nuts in the Human Diet: Measured Energy Value and Effects on Cardiovascular Disease Risk Factors

NCT02628171
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Base Diet, Base Diet with Cashew Nuts
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
25 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 4, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome

NCT05034380
View directory record Official record
Conditions
Obesity, Type 2 Diabetes, Cardiovascular Diseases, Acute Exercise
Interventions
Acute exercise
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 4, 2026, 11:53 AM EDT
Not yet recruiting Phase 3 Interventional

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

NCT07794579
View directory record Official record
Conditions
Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
2,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
79
States / cities
Anniston, Alabama • Birmingham, Alabama • Pelham, Alabama + 73 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 4, 2026, 11:53 AM EDT