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ClinicalTrials.gov public records Last synced Oct 6, 2026, 4:20 AM EDT

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Showing 1–24 of 145 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Carotid Artery Occlusive Disease Clear all
Completed Phase 2 Interventional Results available

Effect of Valsartan on Carotid Artery Disease

NCT00208767
View directory record Official record
Conditions
Carotid Artery Diseases, Atherosclerosis
Interventions
Valsartan, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 6, 2026, 4:20 AM EDT
Terminated Not applicable Interventional

Dental Carotid Cognitive Study

NCT03755362
View directory record Official record
Conditions
Carotid Stenosis, Mild Cognitive Impairment, Periodontitis
Interventions
Standard Treatment, Intensive Treatment
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 100 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 6, 2026, 4:20 AM EDT
Completed Phase 2 Interventional Results available

TRACER [F-18] RDG-K5 Carotid Plaque Imaging Study

NCT03364270
View directory record Official record
Conditions
Carotid Arteries
Interventions
PET/CT Imaging with [F-18] RGD-K5
Drug
Lead sponsor
Balaji Tamarappoo
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Oct 6, 2026, 4:20 AM EDT
Not listed No phase listed Observational

SmartRisk Stroke Prediction by MRI of Carotid Disease

NCT00860184
View directory record Official record
Conditions
Atherosclerotic Disease, Carotid
Interventions
Not listed
Lead sponsor
VPDiagnostics
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
15
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 6, 2026, 4:20 AM EDT
Terminated Phase 3 Interventional Results available

Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes

NCT02850081
View directory record Official record
Conditions
Carotid Artery Stenosis, Strokes
Interventions
Statin, Atorvastatin, Placebo
Drug · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
7
States / cities
Ridgewood, New Jersey • Albany, New York • Buffalo, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 6, 2026, 4:20 AM EDT
Active, not recruiting Not applicable Interventional

Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System

NCT04201132
View directory record Official record
Conditions
Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
Interventions
Carotid artery stenting with Neuroguard IEP System
Device
Lead sponsor
Contego Medical, Inc.
Industry
Eligibility
20 Years to 80 Years
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
28
States / cities
Huntsville, Alabama • St. Helena, California • Washington D.C., District of Columbia + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Oct 6, 2026, 4:20 AM EDT
Active, not recruiting No phase listed Observational

Symptomatic Carotid Outcomes Registry

NCT05300737
View directory record Official record
Conditions
Carotid Stenosis, Ischemic Stroke, Transient Ischemic Attack
Interventions
intensive medical therapy
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
40 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
11
States / cities
Hartford, Connecticut • Atlanta, Georgia • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 6, 2026, 4:20 AM EDT
Completed No phase listed Observational

Diabetes, Lipoproteins and Accelerated Vascular Disease

NCT00005479
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis, Carotid Artery Diseases, Diabetes Mellitus, Non-insulin Dependent, Diabetes Mellitus
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 75 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 28, 2015 · Synced Oct 6, 2026, 4:20 AM EDT
Terminated Phase 2 Interventional Results available

TRACER RGD-K5 Carotid Plaque Imaging Study

NCT01968226
View directory record Official record
Conditions
Carotid Artery Disease, Carotid Stenosis
Interventions
[F-18] RDG-K5
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 12, 2017 · Synced Oct 6, 2026, 4:20 AM EDT
Completed No phase listed Observational

Acoustic Radiation Force Impulse (ARFI) Ultrasound for Noninvasive, Diagnostic Atherosclerosis Imaging

NCT01581385
View directory record Official record
Conditions
Atherosclerosis
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 6, 2026, 4:20 AM EDT
Recruiting Phase 3 Interventional

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

NCT05611242
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
MT+CAS with IV-AP, MT+CAS with PO-AP, MT+CAT with PO-AP
Procedure
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years to 79 Years
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
60
States / cities
Mobile, Alabama • Glendale, California • Irvine, California + 54 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 6, 2026, 4:20 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Women's Isoflavone Soy Health (WISH) Trial

NCT00118846
View directory record Official record
Conditions
Atherosclerosis
Interventions
25 gm soy protein supplement, Placebo
Dietary Supplement · Other
Lead sponsor
University of Southern California
Other
Eligibility
30 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 6, 2026, 4:20 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Transcranial Doppler(TCD) Evaluation of High Intensity Transient Signals and Carotid Disease

NCT05829200
View directory record Official record
Conditions
Asymptomatic Carotid Stenosis, Symptomatic Carotid Stenosis, TCD, HITS
Interventions
Transcranial Doppler (TCD)
Device
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 6, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Short-Term Endogenous Hydrogen Sulfide Upregulation

NCT03303534
View directory record Official record
Conditions
Carotid Stenosis, Caloric Restriction
Interventions
ScandiShake
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 6, 2026, 4:20 AM EDT
Withdrawn Phase 2 Interventional

A Study of the Effects of Minocycline on Cognitive Function After Carotid Endarterectomy

NCT00401921
View directory record Official record
Conditions
Carotid Stenosis
Interventions
Minocycline, Placebo oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2017 · Synced Oct 6, 2026, 4:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media Thickness

NCT00001904
View directory record Official record
Conditions
Atherosclerosis, Myocardial Infarction
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 6, 2026, 4:20 AM EDT
Terminated Phase 4 Interventional Results available

Post-Approval Study of the NexStent Carotid Stent System and the FilterWire EZ Embolic Protection System: SONOMA

NCT00478673
View directory record Official record
Conditions
Carotid Stenosis
Interventions
NexStent Carotid Stent System (Monorail Delivery System), FilterWire EZ™ Embolic Protection System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
62
States / cities
Huntsville, Alabama • Phoenix, Arizona • Bakersfield, California + 54 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Oct 6, 2026, 4:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV

NCT00575939
View directory record Official record
Conditions
HIV Infections, Atherosclerosis
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 6, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional

Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

NCT05723926
View directory record Official record
Conditions
Atrial Fibrillation, Oral Anticoagulation, Stroke, Implant
Interventions
Vine Filter
Device
Lead sponsor
Javelin Medical
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
6
States / cities
Rockford, Illinois • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 6, 2026, 4:20 AM EDT
Completed No phase listed Observational

Identification of Genes Expressed in Atherosclerotic Plaque

NCT00353730
View directory record Official record
Conditions
Atherosclerosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 100 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Oct 6, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional

A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach

NCT06653387
View directory record Official record
Conditions
Carotid Artery Diseases
Interventions
CGuard Prime 80cm stent system
Device
Lead sponsor
InspireMD
Industry
Eligibility
18 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
8
States / cities
Sacramento, California • Indianapolis, Indiana • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 6, 2026, 4:20 AM EDT
Completed No phase listed Observational

Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)

NCT01178320
View directory record Official record
Conditions
Coronary Artery Disease, Carotid Artery Diseases, Atherosclerosis
Interventions
Simvastatin, simvastatin plus extended-release niacin
Drug
Lead sponsor
University of Washington
Other
Eligibility
45 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
15
States / cities
Phoenix, Arizona • Long Beach, California • Los Angeles, California + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2018 · Synced Oct 6, 2026, 4:20 AM EDT
Completed Not applicable Interventional

A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection

NCT00177346
View directory record Official record
Conditions
Carotid Artery Stenosis
Interventions
CAS with cerebral protection, CAS without cerebral protection
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
52 participants
Timeline
2003 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Oct 6, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional

The Symani Restore Study

NCT07140731
View directory record Official record
Conditions
Moyamoya Disease
Interventions
Symani Surgical System
Device
Lead sponsor
Jacobs institute
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 6, 2026, 4:20 AM EDT