- Conditions
- Articular Cartilage of the Femoral Condyle Between 2-6cm2
- Interventions
- Microfracture, NOVOCART 3D
- Procedure · Biological
- Lead sponsor
- Aesculap Biologics, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 233 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2027
- U.S. locations
- 30
- States / cities
- La Mesa, California • Los Angeles, California • Redwood City, California + 26 more
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Showing 1–24
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- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Hormone Receptor Positive Breast Adenocarcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
- Interventions
- Magnetic Resonance Imaging, Questionnaire Administration
- Procedure · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- Up to 70 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Defect of Articular Cartilage, Knee Injuries
- Interventions
- Particulated Juvenile Articular Cartilage
- Other
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2021
- U.S. locations
- 16
- States / cities
- Los Angeles, California • San Deigo, California • Aurora, Colorado + 13 more
- Conditions
- Osteoarthritis, Tendinitis, Sports Injury, Degenerative Disc Disease, Degenerative Arthritis, Ligament Injury, Neuropathy, Pelvic Pain
- Interventions
- Umbilical Allograft
- Other
- Lead sponsor
- R3 Stem Cell
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2030
- U.S. locations
- 1
- States / cities
- Encino, California
- Conditions
- Torn Meniscus
- Interventions
- Mechanical Debridement, Paragon T2, Lavage debridement, RF- based Debridement
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 165 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 10
- States / cities
- Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 6 more
- Conditions
- Cartilage Repair
- Interventions
- Particulated Juvenile Cartilage Allograft
- Biological
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Indianapolis, Indiana • Albuquerque, New Mexico
- Conditions
- Chondral Defect, Articular Cartilage Defect
- Interventions
- autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
- Biological · Procedure
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 17 Years to 65 Years
- Enrollment
- 309 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 7
- States / cities
- Sacramento, California • Washington D.C., District of Columbia • Wichita, Kansas + 4 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 30 Years to 80 Years
- Enrollment
- 906 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
- Interventions
- Not listed
- Lead sponsor
- Global Healthy Living Foundation
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 40,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2025
- U.S. locations
- 1
- States / cities
- Upper Nyack, New York
- Conditions
- Articular Cartilage Defect
- Interventions
- NOVOCART 3D
- Combination Product
- Lead sponsor
- Aesculap Biologics, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2029
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Columbus, Ohio • North Logan, Utah
- Conditions
- Injuries, Knee
- Interventions
- Single Portal Knee Arthroscopy, Two Portal Knee Arthroscopy
- Procedure
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Knee Cartilage Defects
- Interventions
- CARTISTEM® + Debridement, Debridement
- Biological · Procedure
- Lead sponsor
- Medipost, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 30
- States / cities
- Birmingham, Alabama • Scottsdale, Arizona • Tempe, Arizona + 25 more
- Conditions
- Knee Osteoarthritis
- Interventions
- normal activities and clinical care, Concentric Focused Resistance Exercise, Eccentric Focused Resistance Exercise
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 60 Years to 85 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
- Interventions
- Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
- Other
- Lead sponsor
- Creighton University
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Knee Osteoarthritis (OA)
- Interventions
- Collagen Hydrolysate, Placebo
- Dietary Supplement
- Lead sponsor
- GELITA
- Industry
- Eligibility
- 49 Years to 90 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Advanced and/or Metastatic Sarcoma
- Interventions
- Durvalumab, Tremelimumab
- Drug
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee, Knee Injuries, Cartilage, Articular, Gait
- Interventions
- Real-time gait biofeedback, Sham real-time gait biofeedback
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Musculoskeletal Pain, Knee Osteoarthritis, Cartilage Injury, Cartilage Degeneration
- Interventions
- Autologous Mesenchymal Stem Cells
- Biological
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Interventions
- microfracture surgery + HST003
- Biological
- Lead sponsor
- Histogen
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Euflexxa, Magnetic Resonance Imaging (MRI)
- Drug · Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Joint Cartilage Turnover
- Interventions
- Move3™ (NEM® brand eggshell membrane + KD PUR® brand fish oil), Placebo
- Dietary Supplement
- Lead sponsor
- ESM Technologies, LLC
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Springfield, Missouri
- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 40 Years and older · Female only
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Hip Osteoarthritis, Hip Impingement Syndrome, Cartilage Damage, Fibrosis
- Interventions
- Losartan, Placebo
- Drug · Other
- Lead sponsor
- Steadman Philippon Research Institute
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Vail, Colorado
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee, Cartilage or Osteochondral Defects in the Knee, Cartilage Lesion
- Interventions
- BioPoly, surgical standard of care (SSOC)
- Device · Procedure
- Lead sponsor
- BioPoly LLC
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 4
- States / cities
- Fort Wayne, Indiana • Indianapolis, Indiana • Rochester, Minnesota + 1 more