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Active, not recruiting Phase 3 Interventional

NOVOCART®3D for Treatment of Articular Cartilage of the Knee

ClinicalTrials.gov ID: NCT01957722

Public ClinicalTrials.gov record NCT01957722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 10:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Prospective, Randomized, Partially Blinded Multi-Center Study to Measure the Safety and Efficacy of NOVOCART 3D Compared ot Microfracture in the Treatment of Articular Cartilage Defects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is to compare NOVOCART 3D relative to Microfracture for the treatment of knee cartilage defects. Efficacy will be evaluated by both pain and function. Safety will also be evaluated.

Study identification

NCT ID
NCT01957722
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Aesculap Biologics, LLC
Industry
Enrollment
233 participants

Conditions and interventions

Interventions

Procedure · Biological

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2013
Primary completion
Nov 30, 2025
Completion
Nov 30, 2027
Last update posted
Mar 20, 2025

2013 – 2027

United States locations

U.S. sites
30
U.S. states
17
U.S. cities
29
Facility City State ZIP Site status
Grossmont Orthopaedic Medical Group La Mesa California 91942
UCLA Los Angeles California 90095
Stanford Medicine Redwood City California 94063
Cu Sports Medicine Denver Colorado 80222
Yampa Valley Medical Center Steamboat Springs Colorado 80487
Tenet Florida Physician Services Boca Raton Florida 33433
Paley Orthopedic and Spine Institute West Palm Beach Florida 33407
Saint Alphonsus Medical Group Meridian Idaho 83642
Rush University Medical Center Chicago Illinois 60612
Northshore University Health System Evanston Illinois 60201
University of Kentucky Lexington Kentucky 40536
Ochsner Health System New Orleans Louisiana 70121
University of Michigan Ann Arbor Michigan 48106
Tria Orthopaedic Center Bloomington Minnesota 55431
Mayo Clinic Rochester Minnesota 55905
University of Missouri Healthcare Columbia Missouri 65212
Mount Sinai Faculty Practice Associates New York New York 10029
Plancher Orthopaedics & Sports Medicine New York New York 10128
Long Island Bone and Joint Llp Port Jefferson New York 11777
Ohio State University Sports Medicine Columbus Ohio 43221
Tulsa Bone and Joint Associates Tulsa Oklahoma 74146
St. Luke'S University Health Network Bethlehem Pennsylvania 18015
Penn State Hershey Medical Center Hershey Pennsylvania 17033
Temple University Hospital Philadelphia Pennsylvania 19140
Allegheny - Singer Research Institute Pittsburgh Pennsylvania 15212
Clinical Research Solutions Jackson Tennessee 38305
Alpine Orthopaedics North Logan Utah 84341
University of Virginia Charlottesville Virginia 22908
The Orthopaedic Center of Central Virginia Inc Lynchburg Virginia 24501
Advanced Orthopaedics Richmond Virginia 23294

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01957722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 20, 2025 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01957722 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →