- Conditions
- Defect of Articular Cartilage
- Interventions
- Not listed
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
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Showing 1–24
of 25
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Defect of Articular Cartilage, Knee Injuries
- Interventions
- Particulated Juvenile Articular Cartilage
- Other
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2021
- U.S. locations
- 16
- States / cities
- Los Angeles, California • San Deigo, California • Aurora, Colorado + 13 more
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee, Cartilage or Osteochondral Defects in the Knee, Cartilage Lesion
- Interventions
- BioPoly, surgical standard of care (SSOC)
- Device · Procedure
- Lead sponsor
- BioPoly LLC
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 4
- States / cities
- Fort Wayne, Indiana • Indianapolis, Indiana • Rochester, Minnesota + 1 more
- Conditions
- Articular Cartilage Defects in the Knee Joint
- Interventions
- GelrinC, Microfracture historical control arm
- Device · Other
- Lead sponsor
- Regentis Biomaterials
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 181 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 13
- States / cities
- La Mesa, California • Orange, California • Denver, Colorado + 10 more
- Conditions
- Chondral Defect, Osteochondritis Dissecans (OCD), Articular Cartilage Defect, Articular Cartilage Disorder of Knee
- Interventions
- MACI, microfracture
- Biological · Procedure
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 12
- States / cities
- Palo Alto, California • Sacramento, California • New Orleans, Louisiana + 7 more
- Conditions
- Cartilage Defect
- Interventions
- Autologous Chondrocytes in their Pericellular Matrix (Chondrons) Coimplanted with Allogeneic Adipose-Derived Mesenchymal Stromal Cells (AMSCs) in a Fibrin Glue Carrier
- Combination Product
- Lead sponsor
- Daniel B. F. Saris
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Defect of Articular Cartilage
- Interventions
- Hyalofast, Microfracture
- Device · Procedure
- Lead sponsor
- Anika Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2026
- U.S. locations
- 18
- States / cities
- Tempe, Arizona • Los Angeles, California • San Diego, California + 14 more
- Conditions
- Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
- Interventions
- Neocartilage Implant/DeNovo® ET (Engineered Tissue Graft), Microfracture
- Biological · Other
- Lead sponsor
- ISTO Technologies, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2020
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Santa Monica, California • Chicago, Illinois + 5 more
- Conditions
- Cartilage Defect
- Interventions
- REcycled CartiLage Auto/Allo IMplantation
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Chondral Lesion Plus Partial Medial Meniscectomy
- Interventions
- Mechanical Debridement, RF-Based Debridement
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 7
- States / cities
- Tucson, Arizona • Gulf Breeze, Florida • Greenwood, Indiana + 4 more
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Interventions
- microfracture surgery + HST003
- Biological
- Lead sponsor
- Histogen
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more
- Conditions
- Articular Cartilage Defect, Articular Cartilage Degeneration
- Interventions
- Autologous Chondrocyte Implantation (CartiLife®)
- Drug
- Lead sponsor
- Biosolution Co., Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Irvine, California • La Mesa, California • Lafayette, Louisiana + 1 more
- Conditions
- Chondral Lesion of the Knee, Meniscal Injuries, Cartilage Defects of the Knee, Osteoarthritis (OA) of the Knee
- Interventions
- Bone Marrow Aspirate (BMA), Arthroscopic Debridement Surgery, Saline
- Biological · Procedure · Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Symptomatic Osteochondral Defect(s), Cartilage, Meniscus, Ankle, Knee, Shoulder, Hip
- Interventions
- Standard of care osteochondral and or meniscal allograft transplantation
- Procedure
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 13 Years and older
- Enrollment
- 5,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2050
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Cartilage Injury, Cartilage Damage
- Interventions
- Cryopreserved Osteochondral Allograft
- Procedure
- Lead sponsor
- AlloSource
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2028
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Lexington, Kentucky • Cincinnati, Ohio
- Conditions
- Degeneration Articular Cartilage Knee
- Interventions
- CARTISTEM®
- Biological
- Lead sponsor
- Medipost, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Chestnut Hill, Massachusetts
- Conditions
- Cartilage Injury, Cartilage Damage
- Interventions
- Articular cartilage repair
- Other
- Lead sponsor
- AlloSource
- Industry
- Eligibility
- Not listed
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Mobile, Alabama • Wheat Ridge, Colorado • Washington D.C., District of Columbia + 2 more
- Conditions
- Defect of Articular Cartilage, Osteochondritis Dissecans
- Interventions
- Microfracture, Cartilage Autograft Implantation System
- Procedure · Device
- Lead sponsor
- DePuy Mitek
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 27
- States / cities
- Tucson, Arizona • Bentonville, Arkansas • Encinitas, California + 24 more
- Conditions
- Chondral Defect, Articular Cartilage Defect
- Interventions
- autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
- Biological · Procedure
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 17 Years to 65 Years
- Enrollment
- 309 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 7
- States / cities
- Sacramento, California • Washington D.C., District of Columbia • Wichita, Kansas + 4 more
- Conditions
- Articular Cartilage Defect Grade III or IV of the Knee
- Interventions
- Autologous Cell, Standard microfracture arthroscopic surgery
- Procedure
- Lead sponsor
- Fondren Orthopedic Group L.L.P.
- Other
- Eligibility
- 18 Years to 68 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Microtia, Congenital, Microtia, Microtia-Anotia, Ear Deformities, Acquired, Ear Deformity External, Ear Malformation, Ear Cartilage
- Interventions
- Use of AuryzoN™ EAR 2.0 device, Hand carving
- Procedure
- Lead sponsor
- Nemours Children's Clinic
- Other
- Eligibility
- 5 Years to 20 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Orlando, Florida
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease, Osteochondral Lesion, Hip Dysplasia
- Interventions
- ReNew Hip Implant
- Device
- Lead sponsor
- Cytex Therapeutics, Inc.
- Other
- Eligibility
- 14 Years to 64 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2031
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Articular Cartilage Defect
- Interventions
- NOVOCART 3D
- Combination Product
- Lead sponsor
- Aesculap Biologics, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2029
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Columbus, Ohio • North Logan, Utah
- Conditions
- Defect of Articular Cartilage, Osteochondral Lesion of Talus, Osteochondritis Dissecans
- Interventions
- DeNovo NT Natural Tissue Graft
- Other
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 205 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 8
- States / cities
- Sacramento, California • Honolulu, Hawaii • Baltimore, Maryland + 5 more