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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:08 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 104 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cartilage Diseases Clear all

Conditions: Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease, Osteochondral Lesion, Hip Dysplasia
Interventions: ReNew Hip Implant; Device
Lead sponsor: Cytex Therapeutics, Inc.; Other
Eligibility: 14 Years to 64 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Osteoarthritis
Interventions: Cartiva; Device
Lead sponsor: Cartiva, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 5
States / cities: San Diego, California • Atlanta, Georgia • Indianapolis, Indiana + 2 more

Conditions: Sprain, Strain
Interventions: Ketoprofen Topical Patch 20%; Drug
Lead sponsor: Alkemira SA; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Osteoarthritis, Knee
Interventions: Vitamin D (cholecalciferol), Placebo; Dietary Supplement
Lead sponsor: Tufts Medical Center; Other
Eligibility: 45 Years to 90 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Cancer, Colorectal Cancer
Interventions: BenFin, placebo; Drug · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 16
States / cities: Scottsdale, Arizona • Jacksonville, Florida • Peoria, Illinois + 13 more

Conditions: Relapsing Polychondritis
Interventions: Abatacept; Drug
Lead sponsor: Benaroya Research Institute; Other
Eligibility: 18 Years to 80 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Nasal Obstruction
Interventions: Nasal Implant; Device
Lead sponsor: Spirox, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 12
States / cities: Beverly Hills, California • Boca Raton, Florida • Boynton Beach, Florida + 8 more

Conditions: Knee Injuries, Cartilage Injury, Cartilage Disease, Knee Discomfort
Interventions: Microfracture, Microfracture plus placement of Chondro-Gide® ACC; Procedure · Device
Lead sponsor: Geistlich Pharma AG; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 3
States / cities: Phoenix, Arizona • Stamford, Connecticut • Johns Creek, Georgia

Conditions: Advanced and/or Metastatic Sarcoma
Interventions: Durvalumab, Tremelimumab; Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Ear Deformities, Acquired, Ear; Deformity, Congenital, Microtia, Nose Deformity, Nose Deformities, Acquired, Nose; Deformity, Congenital, Nose; Deformity, Congenital, Bent or Squashed, Nose; Deformity, Syphilitic, Congenital, Nose; Deformity, Bone (Nose Cartilage), Nose; Deformity, Septum, Congenital, Nose; Deformity, Sinus (Wall), Congenital, Nose; Deformity, Syphilitic, Late (Etiology), Ear; Deformity, External, Ear; Deformity, Auricle, Ear, Acquired, Ear; Deformity, Auricle, Ear (Congenital)
Interventions: AuryzoN Family of Devices; Device
Lead sponsor: Reconstrata, LLC; Industry
Eligibility: Not listed
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
Interventions: Lumbopelvic Manipulation, TENS- Spine, TENS- Knee; Other
Lead sponsor: Creighton University; Other
Eligibility: 15 Years to 50 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Takayasu's Arteritis, Giant Cell Arteritis, Polyarteritis Nodosa, Relapsing Polychondritis, ANCA-Associated Vasculitis
Interventions: Not listed
Lead sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); NIH
Eligibility: 3 Years and older
Enrollment: 4,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2050
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obesity, Osteoarthritis, Knee Osteoarthritis
Interventions: Weight Loss; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Degenerative Disc Disease
Interventions: NuQu, Placebo; Biological · Other
Lead sponsor: ISTO Technologies, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 10
States / cities: Birmingham, Alabama • San Francisco, California • Santa Monica, California + 7 more

Conditions: Meniscus Tear, Chondropathy/Degenerative Joint Disease (DJD)
Interventions: Euflexxa, Saline; Device · Other
Lead sponsor: The Hawkins Foundation; Other
Eligibility: 40 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Osteoarthritis of the Hip, Degenerative Joint Disease of Hip, Dysplasia; Hip
Interventions: Polymotion Hip Resurfacing (PHR) System; Device
Lead sponsor: JointMedica Inc.; Other
Eligibility: 21 Years to 65 Years
Enrollment: 238 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 8
States / cities: Tampa, Florida • Chicago, Illinois • Baltimore, Maryland + 5 more

Conditions: Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
Interventions: microfracture surgery + HST003; Biological
Lead sponsor: Histogen; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 5
States / cities: Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more

Conditions: Osteoarthritis
Interventions: Lateral wedge orthotic shoe inserts, Standard orthotic shoe inserts; Device
Lead sponsor: Rush University Medical Center; Other
Eligibility: 25 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sprain, Strain, Acute Soft Tissue Injury
Interventions: Topical Ketoprofen 10% Cream, Topical Placebo Cream; Drug
Lead sponsor: Imprimis Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 364 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tracheomalacia
Interventions: Dynamic Airway CT scan (DA-CT); Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 0 Years to 18 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: New York, New York

Conditions: Chondral Defect, Osteochondritis Dissecans (OCD), Articular Cartilage Defect, Articular Cartilage Disorder of Knee
Interventions: MACI, microfracture; Biological · Procedure
Lead sponsor: Vericel Corporation; Industry
Eligibility: 10 Years to 17 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2030
U.S. locations: 15
States / cities: Palo Alto, California • Sacramento, California • New Orleans, Louisiana + 10 more

Conditions: Knee Osteoarthristis
Interventions: Exercise with Rest, Exercise without Rest; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 45 Years to 79 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Osteoarthritis
Interventions: Synvisc; Device
Lead sponsor: Endeavor Health; Other
Eligibility: 40 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 2
States / cities: Chicago, Illinois • Evanston, Illinois

Conditions: Osteoarthritis, Knee
Interventions: Fisetin, Placebo oral capsule; Dietary Supplement · Drug
Lead sponsor: Steadman Philippon Research Institute; Other
Eligibility: 40 Years to 80 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Vail, Colorado

Search by objective public record fields.

Early Feasibility Study of Cartilage Defect Repair

Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)

Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain

Vitamin D to Slow Progression of Knee Osteoarthritis

Shark Cartilage in Treating Patients With Advanced Colorectal or Breast Cancer

Study on the Safety of Abatacept in Relapsing Polychondritis

Spirox Latera™ Implant Support of Lateral Nasal Wall Cartilage (LATERAL-OR) Study

Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee

Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes

Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures

Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

Reducing Obesity and Cartilage Compression in Knees

A Study Comparing the Safety and Effectiveness of Cartilage Cell Injected Into the Lumbar Disc as Compared to a Placebo

Post-op Treatment With Hyaluronic Acid Injections

Evaluate the Safety and Effectiveness of the Polymotion Hip Resurfacing (PHR) System Compared to Total Hip Arthroplasty

Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage

A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain

Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury

Dynamic Airway CT is Diagnostic for Tracheomalacia in Children

A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis

Effects of Synvisc on Cartilage in Knee Osteoarthritis (OA)

Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial