Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 5, 2026, 10:42 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 16,396 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Central Nervous System Disorder Clear all

Conditions: Myelofibrosis, Gaucher Disease, Pulmonary Fibrosis, Hermansky-Pudlak Syndrome (HPS), Cancer
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 2 Years to 80 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Spinal Muscular Atrophy
Interventions: Nusinersen, Sham Procedure; Drug · Procedure
Lead sponsor: Biogen; Industry
Eligibility: Not listed
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 6
States / cities: Los Angeles, California • Hartford, Connecticut • Baltimore, Maryland + 3 more

Conditions: Migraine
Interventions: Sounds; Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Prion Disease
Interventions: PrP-siRNA; Drug
Lead sponsor: Broad Institute of MIT and Harvard; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 5
States / cities: Boston, Massachusetts • Rochester, Minnesota • New York, New York + 2 more

Conditions: Brain Concussion
Interventions: Aerobic Exercise, Non-Aerobic Exercise; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 40 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Kennedy's Disease, Spinal and Bulbar Muscular Atrophy
Interventions: Dutasteride, Placebo; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older · Male only
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Migraine Headaches
Interventions: acupuncture; Procedure
Lead sponsor: Memorial Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Johnstown, Pennsylvania

Conditions: Migraine Disorders, Migraine, Acute
Interventions: TREXIMET®, Butalbital-containing Combination Medications (BCM), placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 107
States / cities: Chandler, Arizona • Gilbert, Arizona • Litchfield Park, Arizona + 94 more

Conditions: Congenital Heart Disease, Periventricular Leucomalacia, Brain Development, Cardiac Surgery, Neurodevelopmental Disability, Fetal Neuroprotection
Interventions: Progesterone, Vaginal lubricant; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Not listed
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: MELAS Syndrome
Interventions: Arginine and citrulline supplementations; Dietary Supplement
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 3 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Alzheimer Disease, Dementia, Mild Cognitive Impairment
Interventions: Not listed
Lead sponsor: UsAgainstAlzheimer's; Other
Eligibility: 18 Years to 100 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Spinal Cord Injury
Interventions: Vitamin D and Calcium; Dietary Supplement
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Alzheimer Disease
Interventions: Tricaprilin; Drug
Lead sponsor: Cerecin; Industry
Eligibility: 50 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Brain Injuries, Traumatic, Repetitive Transcranial Magnetic Stimulation, Memory Deficits, Aging
Interventions: Repetitive Transcranial magnetic Stimulation; Device
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 50 Years to 75 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Stroke
Interventions: Group-Based Education, Individualized Coaching; Behavioral
Lead sponsor: University of Texas, El Paso; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: El Paso, Texas

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: ORT247, Placebo; Drug
Lead sponsor: Orthogonal Neuroscience Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Stuttering, Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
Interventions: The Blank Center CARE Model(TM) for Individuals who Stutter; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 2 Years to 85 Years
Enrollment: 3,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2035
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Carotid Artery Stenosis, Carotid Artery Disease, Transient Ischemic Attack, Stroke
Interventions: Carotid endarterectomy, Neurological and neuropsychological evaluations; Procedure · Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 817 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Dementia, Alzheimer Disease, Mild Cognitive Impairment, Worried Well
Interventions: electronic self administered gerocognitive examination (eSAGE); Diagnostic Test
Lead sponsor: Douglas Scharre; Other
Eligibility: 50 Years and older
Enrollment: 1,486 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Angelman Syndrome
Interventions: OV101 Regimen 1, OV101 regimen 2, Placebo; Drug · Other
Lead sponsor: Healx AI; Industry
Eligibility: 13 Years to 49 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 12
States / cities: Phoenix, Arizona • San Diego, California • Gainesville, Florida + 9 more

Conditions: Parkinson Disease
Interventions: Not listed
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: New Hartford, New York

Conditions: Spinal Cord Injury
Interventions: Manual and mechanical assisted cough, Incentive spirometry; Behavioral
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 70 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Leukemia, Lymphoma, Metastatic Cancer, Retinoblastoma, Sarcoma
Interventions: busulfan; Drug
Lead sponsor: Pediatric Brain Tumor Consortium; Network
Eligibility: 3 Years to 21 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2000
U.S. locations: 8
States / cities: San Francisco, California • Washington D.C., District of Columbia • Boston, Massachusetts + 5 more

Conditions: Migraine Disorders
Interventions: gammaCore Sapphire active, gammaCore Sapphire Sham; Device
Lead sponsor: ElectroCore INC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 231 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 30
States / cities: Scottsdale, Arizona • Carlsbad, California • Palo Alto, California + 27 more

Search by objective public record fields.

Clinical and Pathophysiological Investigations Into Erdheim Chester Disease

A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA).

Prevalence of Phonophobia and Cutaneous Allodynia in Episodic Migraineurs

PrP-targeting siRNA Safety & Mechanism Study

The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury

Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)

Set Point Acupuncture for Migraines Using a Digital Assistant

TREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in Adults

Randomized Trial of Maternal Progesterone Therapy

Nitric Oxide Production in MELAS Syndrome

The A-LIST WMM Insights Series

Vitamin D and Calcium Study

Study to Compare the Pharmacokinetics of Daily Administration of Tricaprilin on Ketone Body Production

Efficacy of Repetitive Transcranial Magnetic Stimulation for Improvement of Memory in Older Adults With TBI

United4Stroke (U4S) - El Paso Network Stroke Community Program

A First in Human Study of ORT247 in Healthy Volunteers

Exploring the Nature, Assessment and Treatment of Stuttering

Neuropsychometric Outcome After Carotid Endarterectomy

Integrating eSAGE With EHR Data Using Machine Learning for the Early Detection and Monitoring of Cognitive Impairment in Individuals

A Study in Adults and Adolescents With Angelman Syndrome (STARS)

Pilot Randomized Controlled Trial of Telemedicine for Individuals With Parkinson Disease in a Rural Population

Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines