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ClinicalTrials.gov public records Last synced Oct 6, 2026, 1:05 AM EDT

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Showing 25–48 of 222 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cerebral Blood Flow Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transcranial Near-Infrared Light in Healthy Subjects: a Cerebral Blood Flow Study With Diffuse Correlation Spectroscopy

NCT03740152
View directory record Official record
Conditions
Cognitive Change
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study: Diet and Exercise Study to Improve Brain Blood Flow: Blood Flow Improvement Trial

NCT03117829
View directory record Official record
Conditions
PreDiabetes
Interventions
Diet and Exercise
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Oct 6, 2026, 1:05 AM EDT
Withdrawn No phase listed Observational

Intraoperative Optical Imaging of Brain Function

NCT00632437
View directory record Official record
Conditions
Brain Tumor
Interventions
Speckle-Contrast Imaging
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Added Sugar Intake on Brain Blood Flow and Hippocampal Function in Midlife Adults

NCT05211726
View directory record Official record
Conditions
Aging, Healthy Diet
Interventions
Low Added Sugar Diet, High Added Sugar Diet
Other
Lead sponsor
University of Delaware
Other
Eligibility
50 Years to 64 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Phase 1 Interventional Results available

Reperfusion With Cooling in Cerebral Acute Ischemia

NCT01585597
View directory record Official record
Conditions
Stroke, Acute
Interventions
Zoll- Coolgaurd 3000
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Blood Flow Restriction and Exercise in Parkinson's Disease

NCT07221994
View directory record Official record
Conditions
Parkinson' Disease
Interventions
Blood flow restriction (BFR) and aerobic exercise via recumbent stepping (Nu-Step)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of KETO5 XOGenius Beverage on Markers of Physiological and Neurocognitive Health

NCT06318390
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
Interventions
XO Genius
Dietary Supplement
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 6, 2026, 1:05 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Blood Flow Regulation and Concussions

NCT02754206
View directory record Official record
Conditions
Brain Concussion, Post-Concussion Syndrome
Interventions
Not listed
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 30 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Caloric Stimulation on Cerebral Blood Flow

NCT01629901
View directory record Official record
Conditions
Healthy Volunteer
Interventions
ThermoNeuroModulation (TNM) Device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 6, 2026, 1:05 AM EDT
Completed No phase listed Observational

Individual Blood Pressure Optimization Based on Cerebral Autoregulation After Implantation of Continuous-flow LVAD

NCT03093012
View directory record Official record
Conditions
Heart-Assist Devices, Heart Failure
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 6, 2026, 1:05 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Cardiovascular and Neurovascular Regulation in GWI

NCT04586049
View directory record Official record
Conditions
Brain Blood Flow, Neurovascular Control
Interventions
MRI, Transcranial Doppler Ultrasound, Sympathetic Nerve Activity
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 68 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Withdrawn No phase listed Observational

Noninvasive Monitoring of Cerebral Blood Flow Autoregulation in Patients With Traumatic Brain Injury (TBI)

NCT01605838
View directory record Official record
Conditions
Traumatic Brain Injury (TBI)
Interventions
Not listed
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Oct 6, 2026, 1:05 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Brain Blood Vessel Responses to Changes in Blood Flow

NCT06629077
View directory record Official record
Conditions
Magnetic Resonance Imaging, Cerebrovascular Circulation
Interventions
MRI, Prazosin, Placebo
Device · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 69 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Early Phase 1 Interventional Results available

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

NCT04620382
View directory record Official record
Conditions
Neurogenic Orthostatic Hypotension, Autonomic Failure, Pure Autonomic Failure, Multiple System Atrophy, Parkinson Disease
Interventions
Midodrine, Placebo pill, Abdominal compression, sham compression
Drug · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multimodal MRI Characteristics of Psychotherapy Response in Late Life Depression

NCT02440815
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Problem Solving Therapy
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 6, 2026, 1:05 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers

Identification of microRNAs Involved in Cerebral Collateral Regulation

NCT03905434
View directory record Official record
Conditions
Cerebrovascular Disorders
Interventions
miRNA sampling
Genetic
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
2
States / cities
Columbus, Ohio • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional

Stimulation of External Carotid Artery Circulation

NCT07402954
View directory record Official record
Conditions
Migraine
Interventions
Cadwell Cascade 32 PRO
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Early Phase 1 Interventional

Enhanced External Counterpulsation and Its Effects on Vascular Hemodynamics in Cognitively Impaired Patients

NCT01659398
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
External Counterpulsation (EECP)
Device
Lead sponsor
Patrick Moriarty, MD, FACP, FACC
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Phase 2 Interventional Results available

The Effects of Normalizing Blood Pressure on Cerebral Blood Flow in Hypotensive Individuals With Spinal Cord Injury

NCT02893553
View directory record Official record
Conditions
Spinal Cord Injury, Autonomic Dysreflexia, Baroreceptor Integrity, Sympathetic Integrity, Vagal Integrity, Autonomic Integrity, Hypotensive, Cognitive Function, Cerebral Blood Flow, Blood Pressure
Interventions
Midodrine Hydrochloride, Pyridostigmine Bromide, Mirabegron, Placebo
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 6, 2026, 1:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Transcranial Doppler Using Wearable Ultrasound Patch

NCT06073145
View directory record Official record
Conditions
Medical Device Complication, Brain Injuries, Brain Diseases, Stroke, Vasospasm
Interventions
conventional transcranial Doppler probe and wearable ultrasound patch.
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Oct 6, 2026, 1:05 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)

NCT06682767
View directory record Official record
Conditions
Cerebral Blood Flow, APOE 4
Interventions
FMD1 (LNT22-017-1), Rapamycin, Placebo
Dietary Supplement · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
45 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Phase 2 Interventional Results available

Bolus of Saline in Stroke

NCT01971463
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Normal saline
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 110 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Oct 6, 2026, 1:05 AM EDT
Completed No phase listed Observational

Monitoring of Cerebral Blood Flow Autoregulation Using Near Infrared Spectroscopy

NCT00769691
View directory record Official record
Conditions
Cardiacsurgery
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 6, 2026, 1:05 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Modulation of Cerebral Blood Flow Using Iron Chelators

NCT01365104
View directory record Official record
Conditions
Stroke, Problem of Aging
Interventions
desferrioxamine
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2015 · Synced Oct 6, 2026, 1:05 AM EDT