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ClinicalTrials.gov public records Last synced Sep 27, 2026, 4:41 AM EDT

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Showing 1–24 of 3,368 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cerebral Vascular Disease Clear all
Completed Early Phase 1 Interventional

Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke

NCT03352232
View directory record Official record
Conditions
Stroke, Motor Dysfunction, Chronic Stroke, Ischemic Stroke
Interventions
HBOT and OMT
Combination Product
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Abington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VNS-supplemented Motor Retraining After Stroke

NCT04088578
View directory record Official record
Conditions
Stroke, Acute
Interventions
Training, Vagus Nerve Stimulation, Sham Stimulation
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke

NCT04026399
View directory record Official record
Conditions
Stroke, Physical Disability
Interventions
peripheral vibration stimulation, therapy
Other · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2021 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 2 Interventional

ReoPro and Retavase to Treat Acute Stroke

NCT00046293
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Reopro, Retrovase
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 27, 2026, 4:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Elastin Mediated Vascular Stiffness on End Organs

NCT02840448
View directory record Official record
Conditions
Williams Syndrome, Supravalvular Aortic Stenosis, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
3 Years to 85 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2024
U.S. locations
2
States / cities
Bethesda, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 1 Interventional

Aclarubicin for the Treatment of Retinal Vasculopathy With Cerebral Leukodystrophy

NCT02723448
View directory record Official record
Conditions
Vasculopathy, Retinal, With Cerebral Leukodystrophy, Cerebroretinal Vasculopathy, Hereditary
Interventions
aclarubicin
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Peripheral Nerve Stimulation for Shoulder Pain: Dose Response

NCT02928055
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 27, 2026, 4:41 AM EDT
Not yet recruiting Early Phase 1 Interventional

Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques

NCT06957821
View directory record Official record
Conditions
Carotid Artery Diseases, Peripheral Arterial Disease
Interventions
Pegulicianine, Placebo
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 3 Interventional Results available

Gadobutrol Enhanced MRA of the Supra-aortic Vessels

NCT01344447
View directory record Official record
Conditions
Carotid Stenosis
Interventions
Gadobutrol (Gadovist, BAY86-4875)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
479 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
15
States / cities
Tucson, Arizona • Jacksonville, Florida • Savannah, Georgia + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 3 Interventional

Hypothermia During Intracranial Aneurysm Surgery Trial

NCT00029133
View directory record Official record
Conditions
Aneurysm, Hypothermia, Subarachnoid Hemorrhage
Interventions
mild intraoperative hypothermia (33 degrees Celsius)
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
19 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Evaluating the Indego Exoskeleton for Persons With Hemiplegia Due to CVA

NCT03054064
View directory record Official record
Conditions
Cerebrovascular Accident (CVA), Stroke, Hemiplegia
Interventions
Indego Exoskeleton
Device
Lead sponsor
Parker Hannifin Corporation
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
7
States / cities
Los Angeles, California • Atlanta, Georgia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Sep 27, 2026, 4:41 AM EDT
Completed No phase listed Observational Results available

Philips Intracardiac Echocardiography (ICE) Clinical Registry

NCT04950192
View directory record Official record
Conditions
Atrial Fibrillation, Stroke, Valve Disease, Heart, Atrial Septal Defect, Patent Foramen Ovale, Mitral Valve Disease, Tricuspid Valve Disease, Aortic Valve Disease
Interventions
ICE Image guidance
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Aurora, Colorado • Chicago, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2025 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 4 Interventional

Trial of Parkinson's And Zoledronic Acid

NCT03924414
View directory record Official record
Conditions
Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies
Interventions
Zoledronic Acid 5Mg/Bag 100Ml Inj, Placebo
Drug · Other
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
60 Years and older
Enrollment
2,721 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
77
States / cities
Scottsdale, Arizona • Fayetteville, Arkansas • Little Rock, Arkansas + 58 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional

REEV SENSE for Gait Analysis in Post-stroke Gait Impairment (SENS-AG)

NCT06234878
View directory record Official record
Conditions
Stroke, Gait Disorders, Neurologic
Interventions
REEV SENSE, Motion capture system
Device
Lead sponsor
REEV LLC
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Exploring Advanced Imaging Techniques to Characterize Botulinum Toxin Diffusion in Human Muscle

NCT01412008
View directory record Official record
Conditions
Stroke, Muscle Spasticity
Interventions
Botox (botulinum toxin)
Drug
Lead sponsor
New York Presbyterian Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Sep 27, 2026, 4:41 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

fMRI Neurofeedback for Motor Rehabilitation

NCT02089776
View directory record Official record
Conditions
Stroke, fMRI
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 3 Interventional Results available

A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease

NCT01176240
View directory record Official record
Conditions
Orthostatic Hypotension, Parkinson's Disease
Interventions
Droxidopa, Placebo
Drug · Other
Lead sponsor
Chelsea Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
60
States / cities
Alabaster, Alabama • Gilbert, Arizona • Phoenix, Arizona + 53 more
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Goode Health Beverage on Markers of Physiological and Neurocognitive Health

NCT06245382
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
Interventions
Goode Health Beverage, Vanilla Base Beverage Blend
Dietary Supplement
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 55 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 27, 2026, 4:41 AM EDT
Recruiting No phase listed Observational

NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

NCT06604884
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Treatment of Intracranial Aneurysms
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years and older
Enrollment
118 participants
Timeline
2025 – 2033
U.S. locations
9
States / cities
Jacksonville, Florida • Marietta, Georgia • Evanston, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Sub-Acute Stroke Rehabilitation With AMES

NCT00609115
View directory record Official record
Conditions
Cerebrovascular Stroke
Interventions
AMES device (test), AMES device (sham), AMES device (crossover)
Device
Lead sponsor
AMES Technology
Industry
Eligibility
18 Years to 80 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Rancho Mirage, California • San Francisco, California • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2022 · Synced Sep 27, 2026, 4:41 AM EDT
Enrolling by invitation No phase listed Observational

Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the LVIS Device

NCT05453240
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Not listed
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aliso Viejo, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Social Work Intervention Focused on Transitions

NCT02232126
View directory record Official record
Conditions
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension, Cancer, Depression, Asthma, Chronic Heart Failure, Chronic Obstructive Pulmonary Disease, Stroke
Interventions
SWIFT home intervention
Other
Lead sponsor
University of Southern California
Other
Eligibility
65 Years to 110 Years
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Los Angeles, California • Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Sep 27, 2026, 4:41 AM EDT
Active, not recruiting Phase 2 Interventional

Regulating Blood Pressure During Recovery From Intracerebral Hemorrhage and Ischemic Stroke

NCT04760717
View directory record Official record
Conditions
Intracerebral Hemorrhage, Ischemic Stroke, Spironolactone
Interventions
Spironolactone Pill
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
5
States / cities
New Haven, Connecticut • Winston-Salem, North Carolina • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 27, 2026, 4:41 AM EDT
Completed Phase 3 Interventional Results available

Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation

NCT00781391
View directory record Official record
Conditions
Stroke, Atrial Fibrillation, Embolism
Interventions
warfarin tablets, Edoxaban tablets (high dose regimen-60mg), Edoxaban tablets (low dose regimen-30mg), placebo warfarin, placebo edoxaban
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
21 Years and older
Enrollment
21,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
316
States / cities
Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 308 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 27, 2026, 4:41 AM EDT