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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cervical Dilation Clear all
Recruiting Not applicable Interventional

Cervical Ripening Balloons for Same-Day Cervical Prep

NCT06964373
View directory record Official record
Conditions
Dilation and Evacuation
Interventions
Cervical Ripening Balloon, Osmotic Dilators
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Results available

DilaCheck Cervical Dilation Measurement Trial

NCT03440723
View directory record Official record
Conditions
Cervical Dilation, Labor Pain, Labor Fast, Labor; Irregular
Interventions
DilaCheck, Cervical dilation examination
Device · Diagnostic Test
Lead sponsor
Elm Tree Medical Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Jul 22, 2026, 7:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks

NCT01636063
View directory record Official record
Conditions
Induced Abortion, Abortion Techniques, Mifepristone, Misoprostol
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Misoprostol Alone to Dilapan With Misoprostol and Comparing Buccal to Vaginal Misoprostol

NCT02363556
View directory record Official record
Conditions
Second Trimester Abortions
Interventions
Misoprostol administered vaginally, Misoprostol administered buccally, Misoprostol administered vaginally with Dilapan, Misoprostol administered buccally with Dilapan
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Results available

Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services

NCT01862991
View directory record Official record
Conditions
Legally Induced Abortion Without Mention of Complication
Interventions
Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin, Mifepristone
Other · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Results available

Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb

NCT02899689
View directory record Official record
Conditions
Pre-induction Dilation of Cervix
Interventions
Dilapan, Foley Catheter
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Jul 22, 2026, 7:01 PM EDT
Withdrawn Not applicable Interventional

Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 Weeks

NCT02679092
View directory record Official record
Conditions
Legally Induced Abortion Without Mention of Complication
Interventions
Misoprostol, Mifepristone, Hygroscopic cervical dilators
Drug · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sound Check-Correlation Between Transperineal and Digital Cervical Exam in 3rd Trimester Pregnancy

NCT05260333
View directory record Official record
Conditions
Cervix; Pregnancy
Interventions
Butterfly iQ transperineal ultrasound exam
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 26, 2023 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional

A Randomized Study on Comparing the Efficacy of Foley Catheter and Extraamniotic Saline Infusion for Labor Induction

NCT00366951
View directory record Official record
Conditions
Cervical Ripening, Labor, Induced
Interventions
Foley catheter only, Extraamniotic saline infusion
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 9, 2008 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Misoprostol With Intrauterine Device Insertion

NCT00613366
View directory record Official record
Conditions
Contraception
Interventions
Misoprostol, Magnesium Oxide
Drug · Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Jul 22, 2026, 7:01 PM EDT
Terminated Not applicable Interventional

Physical Exam Indicated Cerclage in Twin Gestations

NCT02490384
View directory record Official record
Conditions
Twin Pregnancy, Antepartum Condition or Complication, Preterm Birth, Cervical Dilation Premature
Interventions
Physical exam indicated cerclage
Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Albany, New York • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2020 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Results available

Balloon Catheter for Cervical Ripening

NCT02606643
View directory record Official record
Conditions
Cervical Dilation
Interventions
Slight traction, Foley Catheter to no traction
Procedure
Lead sponsor
St. Louis University
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Results available

Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks

NCT01615731
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Jul 22, 2026, 7:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Assessment of DILAPAN-S

NCT04529837
View directory record Official record
Conditions
Cervical Dilation, Induction of Labor, Ultrasound Evaluation
Interventions
Gauze, No gauze
Other
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation

NCT02033083
View directory record Official record
Conditions
Second Trimester Abortion
Interventions
Laminaria, Dilapan-S
Device
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Preparation Before Dilation and Evacuation

NCT01751087
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, misoprostol, Osmotic dilators, placebo
Other · Drug · Device
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
7
States / cities
San Francisco, California • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Phase 4 Interventional Results available

Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion

NCT04254081
View directory record Official record
Conditions
Procedural Pain, Buprenorphine, Adjuvants, Anesthesia, Dilation and Evacuation, Analgesics
Interventions
Buprenorphine 0.15 MG, Lidocaine 1% Injectable Solution
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 22, 2026, 7:01 PM EDT
Recruiting Phase 2Phase 3 Interventional

Anticholinergics for Cervical Edema in Labor

NCT06702670
View directory record Official record
Conditions
Labor Dystocia
Interventions
Treatment with Diphenhydramine, Usual Care
Drug · Combination Product
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Phase 2 Interventional Results available

Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy

NCT00925938
View directory record Official record
Conditions
Cervical Priming
Interventions
misoprostol, placebo
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
2
States / cities
Phoenix, Arizona • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2014 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Self-administered Lidocaine Gel for Pain-control During Cervical Preparation for Dilation and Evacuation

NCT02852434
View directory record Official record
Conditions
Pain Management, Cervical Preparation
Interventions
Lidocaine Gel (2%), Lidocaine Paracervical Block (1%)
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Jul 22, 2026, 7:01 PM EDT
Not listed No phase listed Observational

Pregnancy and Latent Labor Biomarkers and Symptoms to Predict Cervical Dilation at Hospital Admission.

NCT04437576
View directory record Official record
Conditions
Labor Onset Biomarkers, Labor Onset, Cervical Dilation
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 39 Years · Female only
Enrollment
300 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Jul 22, 2026, 7:01 PM EDT
Completed Phase 1 Interventional

Intrauterine Lidocaine for Laminaria

NCT01541293
View directory record Official record
Conditions
Abortion, Induced, Pain Management
Interventions
Lidocaine, Normal Saline
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Jul 22, 2026, 7:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Dilapan-S® for Induction of Labor The Feasibility Study

NCT04521062
View directory record Official record
Conditions
Induction of Labor Affected Fetus / Newborn
Interventions
Dilapan S
Device
Lead sponsor
Albany Medical College
Other
Eligibility
Not listed
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 22, 2026, 7:01 PM EDT
Completed No phase listed Observational

Dilapan-S/Dilasoft E-Registry in Induction of Labor

NCT02318173
View directory record Official record
Conditions
Labour Onset and Length Abnormalities, Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions
Dilapan-S
Device
Lead sponsor
Medicem International CR s.r.o.
Industry
Eligibility
Female only
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
New York, New York • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Jul 22, 2026, 7:01 PM EDT