- Conditions
- Colorectal Cancer, Diarrhea
- Interventions
- loperamide hydrochloride, octreotide acetate
- Drug
- Lead sponsor
- Eastern Cooperative Oncology Group
- Network
- Eligibility
- 18 Years to 120 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1997
- U.S. locations
- 33
- States / cities
- La Jolla, California • San Francisco, California • Wilmington, Delaware + 24 more
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- Conditions
- Cancer Therapy-Related Diarrhea, Chemotherapy-related Diarrhea, Adult Solid Tumor, Prophylaxis of Diarrhea, Symptomatic Relief of Diarrhea, Targeted Therapy-related Diarrhea
- Interventions
- Crofelemer 125 MG [Mytesi], Placebo
- Drug
- Lead sponsor
- Napo Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 287 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 27
- States / cities
- Prescott, Arizona • Anaheim, California • Corona, California + 24 more
- Conditions
- Diarrhea, Unspecified Adult Solid Tumor, Protocol Specific
- Interventions
- Lactobacillus plantarum strain 299v, Lactobacillus acidophilus probiotic, placebo, laboratory biomarker analysis, questionnaire administration, quality-of-life assessment, Bifidobacterium lactis probiotic supplement
- Dietary Supplement · Other · Procedure
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 1
- States / cities
- Stanford, California