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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chronic Low-back Pain Clear all
Completed Not applicable Interventional

Low Back Pain Patient Education Evaluation

NCT00000408
View directory record Official record
Conditions
Low Back Pain
Interventions
Patient education evaluation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2002
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Not applicable Interventional

Comparative Mechanisms of Psychosocial Chronic Pain Treatments

NCT02133976
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
cognitive therapy, mindfulness training, behavioral therapy, treatment as usual
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
521 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Jul 22, 2026, 11:17 PM EDT
Recruiting Phase 1 Interventional

Psilocybin in Chronic Low Back Pain and Depression

NCT06355414
View directory record Official record
Conditions
Chronic Low-back Pain, Depression
Interventions
Psilocybin, Methylphenidate
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 22, 2026, 11:17 PM EDT
Not yet recruiting Not applicable Interventional

Comparing Yoga Nidra, Yoga, and Control Condition on Pain in Individuals With Chronic Low Back Pain

NCT07543835
View directory record Official record
Conditions
Low Back Pain
Interventions
Yoga, Yoga Nidra, Control Condition
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 3 Interventional Results available

Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain

NCT01451385
View directory record Official record
Conditions
Osteoarthritis, Low Back Pain
Interventions
COV795
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
42
States / cities
Tucson, Arizona • Anaheim, California • Buena Park, California + 33 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Jul 22, 2026, 11:17 PM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain

NCT07306364
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
Interventions
Psilocybin 10 mg, Psilocybin 25 mg, Niacin 100 mg
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 2 Interventional

Elderly Back Pain: Comparing Chiropractic to Medical Care

NCT00602901
View directory record Official record
Conditions
Subacute Low Back Pain, Chronic Low Back Pain
Interventions
HVLA-SM, LVVA-SM, Usual medical care
Other · Drug
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
55 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Davenport, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Not applicable Interventional Results available

Stimgenics Open-Label, Post Market Study

NCT03606187
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Stimgenics SCS Programming Approach, Standard SCS Programming Approach
Device
Lead sponsor
Stimgenics LLC
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bloomington, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 3 Interventional

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Low Back Pain.

NCT00315874
View directory record Official record
Conditions
Back Pain
Interventions
Buprenorphine transdermal delivery system
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 1998
U.S. locations
12
States / cities
Phoenix, Arizona • Gainesville, Florida • Plantation, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 13, 2013 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Not applicable Interventional

The Effect of Yoga in Chronic Low Back Pain

NCT01963871
View directory record Official record
Conditions
Low Back Pain
Interventions
Yoga
Other
Lead sponsor
Yvonne Colgrove, PT, PhD
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Jul 22, 2026, 11:17 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Double-Blind Placebo Study on Magnetic Field Therapy in Chronic Lumbar Pain

NCT00407615
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Flex Pad/Static Magnet
Device
Lead sponsor
Weintraub, Michael I., MD, FACP, FAAN
Individual
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
Briarcliff, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2007 · Synced Jul 22, 2026, 11:17 PM EDT
Recruiting Not applicable Interventional

COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL

NCT07532070
View directory record Official record
Conditions
Osteo Arthritis Knee and Hip, Low Back Pain, Insomnia
Interventions
Aerobic physical activity, CBT-I, Combined aerobic physical activity and CBT-I
Behavioral
Lead sponsor
University of Sydney
Other
Eligibility
18 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Antonio, Nevada • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 2 Interventional Results available

Evaluating the Role of Neuroinflammation in Low Back Pain

NCT03106740
View directory record Official record
Conditions
Low Back Pain, Back Pain With Radiation, Back Pain Without Radiation, Back Pain Lower Back Chronic, Back Ache, Pain, Chronic
Interventions
Minocycline Hydrochloride 100mg Capsule, Magnetic Resonance-Positron Emission Tomography Imaging, Placebo Capsule
Drug · Diagnostic Test · Other
Lead sponsor
Marco Loggia
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 2 Interventional

A Study of a Topical Patch (AB001) in Patients With Chronic Low Back Pain

NCT02436824
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
AB001 patch, Placebo patch
Drug · Other
Lead sponsor
Frontier Biotechnologies Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
9
States / cities
Miami, Florida • Naples, Florida • Marietta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Jul 22, 2026, 11:17 PM EDT
Terminated Not applicable Interventional

Acupressure for Insomnia

NCT01378793
View directory record Official record
Conditions
Insomnia
Interventions
Relaxation Acupressure, Stimulating Acupressure
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 3 Interventional Results available

Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain

NCT03581123
View directory record Official record
Conditions
Acute Pain, Low Back Pain, Mechanical
Interventions
Supported-Self Management (SSM), Spinal Manipulation Therapy (SMT), SMT + SSM, Standard Medical Care (SMC)
Behavioral · Other · Combination Product + 1 more
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
3
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Meditation-CBT for Opioid-treated Chronic Low Back Pain

NCT01775995
View directory record Official record
Conditions
Chronic Pain, Low Back Pain
Interventions
Meditation-CBT Intervention + Usual Care, Usual Care Alone
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 15, 2016 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 1 Interventional

Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain

NCT06810245
View directory record Official record
Conditions
Chronic Osteoarthritis Pain, Chronic Low Back Pain
Interventions
PIPE-791, Placebo
Drug
Lead sponsor
Contineum Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Phoenix, Arizona • Marietta, Georgia • Hartsdale, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Recruiting Not applicable Interventional

Chronic Low Back Pain and Osteopathic Manipulation Treatment

NCT07161661
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP), Low Back Pain
Interventions
Usual VA Care, Osteopathic manipulative treatment
Procedure
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Not applicable Interventional

Self-Administered Acupressure for Veterans With Chronic Back Pain

NCT05423145
View directory record Official record
Conditions
Low Back Pain
Interventions
self-administered acupressure
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
297 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 22, 2026, 11:17 PM EDT
Terminated Phase 4 Interventional

Comparison of Intraspinal Nerve Root Stimulation With Dorsal Column Stimulation

NCT00370773
View directory record Official record
Conditions
Back Pain
Interventions
Precision Spinal Cord Stimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Daphne, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 4, 2008 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 3 Interventional Results available

Duloxetine Versus Placebo in Chronic Low Back Pain

NCT00408876
View directory record Official record
Conditions
Back Pain Without Radiation
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
4
States / cities
Fort Myers, Florida • Orlando, Florida • South Miami, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2009 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Not applicable Interventional

Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain

NCT03597191
View directory record Official record
Conditions
Low Back Pain, Chronic Low Back Pain, Subacute Low Back Pain
Interventions
Exercises
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 1, 2019 · Synced Jul 22, 2026, 11:17 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)

NCT00763321
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
ABT-712, Placebo
Drug
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
21 Years to 75 Years
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
31
States / cities
Huntsville, Alabama • Burbank, California • San Diego, California + 27 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2014 · Synced Jul 22, 2026, 11:17 PM EDT